Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity.
暂无分享,去创建一个
M. Frosini | M. Cascio | V. Di Marzo | R. Pertwee | A. Ligresti | L. De Petrocellis | F. Corelli | F. Gado | C. Manera | C. Mugnaini | S. Maione | L. Luongo | F. Aiello | A. Brizzi | S. Boccella | P. Marini | F. Pessina
[1] A. Hazekamp,et al. An Overview of Galenic Preparation Methods for Medicinal Cannabis , 2019, Current Bioactive Compounds.
[2] P. Morales,et al. Cannabinoid Ligands Targeting TRP Channels , 2019, Front. Mol. Neurosci..
[3] J. Szaflarski,et al. Cannabis for the Treatment of Epilepsy: an Update , 2018, Current Neurology and Neuroscience Reports.
[4] J. Maroon,et al. Review of the neurological benefits of phytocannabinoids , 2018, Surgical neurology international.
[5] R. Budriesi,et al. Castanea sativa Mill. Bark Extract Protects U‐373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury , 2017, Journal of cellular biochemistry.
[6] G. Appendino,et al. Phytocannabinoids: a unified critical inventory. , 2016, Natural product reports.
[7] M. Wallace,et al. Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence , 2015, Current Pain and Headache Reports.
[8] S. Dey,et al. Endocannabinoid signaling at the periphery: 50 years after THC. , 2015, Trends in pharmacological sciences.
[9] R. Mechoulam,et al. Early phytocannabinoid chemistry to endocannabinoids and beyond , 2014, Nature Reviews Neuroscience.
[10] M. Cascio,et al. Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist. , 2014, Bioorganic & medicinal chemistry.
[11] L. Premkumar. Transient Receptor Potential Channels as Targets for Phytochemicals , 2014, ACS chemical neuroscience.
[12] M. Maccarrone,et al. Physical activity and the endocannabinoid system: an overview , 2014, Cellular and Molecular Life Sciences.
[13] Robert M. Jones,et al. Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists. , 2013, Journal of medicinal chemistry.
[14] Rizi Ai,et al. Ligand-specific homology modeling of human cannabinoid (CB1) receptor. , 2012, Journal of molecular graphics & modelling.
[15] P. Ganji,et al. Deoxygenation of hydroquinones as a general route to norbornane-fused aromatic systems: an entry into substituted and functionalized dimethano- and methanoanthracenes. , 2012, The Journal of organic chemistry.
[16] M. Frosini,et al. Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. , 2011, Journal of medicinal chemistry.
[17] K. Bley,et al. Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch , 2011, British journal of anaesthesia.
[18] M. Frosini,et al. Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. , 2011, Journal of medicinal chemistry.
[19] S. Hecht,et al. Design, synthesis, and evaluation of an α-tocopherol analogue as a mitochondrial antioxidant. , 2010, Bioorganic & medicinal chemistry.
[20] E. Hermans,et al. Functionally selective cannabinoid receptor signalling: therapeutic implications and opportunities. , 2010, Biochemical pharmacology.
[21] C. Fiorentini,et al. The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating μ-opioid receptors , 2009, PAIN®.
[22] Federico Corelli,et al. New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. , 2009, Journal of medicinal chemistry.
[23] L. Petrocellis,et al. An introduction to the endocannabinoid system: from the early to the latest concepts , 2009 .
[24] B. Roufogalis,et al. ThermoTRP Channels in Nociceptors: Taking a Lead from Capsaicin Receptor TRPV1 , 2008, Current neuropharmacology.
[25] T. Bisogno,et al. Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. , 2007, Bioorganic & medicinal chemistry.
[26] T. Bisogno,et al. In vitro and in vivo pharmacology of synthetic olivetol‐ or resorcinol‐derived cannabinoid receptor ligands , 2006, British journal of pharmacology.
[27] M. Barnes. Sativex®: clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain , 2006, Expert opinion on pharmacotherapy.
[28] A. Makriyannis,et al. Natural cannabinoids: templates for drug discovery. , 2005, Life sciences.
[29] R. Pertwee,et al. Evidence that the plant cannabinoid Δ9‐tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist , 2005, British journal of pharmacology.
[30] T. Bisogno,et al. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. , 2005, Journal of medicinal chemistry.
[31] D. Lynch,et al. N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor. , 2002, Molecular pharmacology.
[32] R. Razdan,et al. Resorcinol derivatives: a novel template for the development of cannabinoid CB(1)/CB(2) and CB(2)-selective agonists. , 2002, The Journal of pharmacology and experimental therapeutics.
[33] C. Bonechi,et al. Conformational analysis of N‐arachidonylethanolamide (anandamide) using nuclear magnetic resonance and theoretical calculations , 2001 .
[34] S. Yu,et al. 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. , 1999, Bioorganic & medicinal chemistry.
[35] R. Pertwee,et al. Agonist‐inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630 , 1999, British journal of pharmacology.
[36] D. Kendall,et al. Ligand Binding and Modulation of Cyclic AMP Levels Depend on the Chemical Nature of Residue 192 of the Human Cannabinoid Receptor 1 , 1998, Journal of neurochemistry.
[37] D. R. Compton,et al. Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. , 1996, Journal of medicinal chemistry.
[38] T. Bonner,et al. A lysine residue of the cannabinoid receptor is critical for receptor recognition by several agonists but not WIN55212-2. , 1996, Molecular pharmacology.
[39] K. Metters,et al. Structure activity relationships of tetrahydrocannabinol analogues on human cannabinoid receptors , 1996 .
[40] L. De Petrocellis,et al. Assay of TRPV1 Receptor Signaling. , 2016, Methods in molecular biology.