[Injectable collagen].

The aim of this paper is to evaluate the so-called "American" injectable collagen, produced since 1975 by Collagen Corporation. Main interest of that work concerns an actual follow-up on millions of patients, treated since 25 years, with more than 280 clinic studies published throughout international literature. Everybody knows that--in human therapeutic--a very long follow-up and a great number of patients is a warranty for a complete security. This Collagen is natural, extracted from bovine dermis; this is the first "true cosmetic drug". Therefore, rigorous practice conditions have to be respected.