Myasthenia gravis and azathioprine treatment: Adverse events related to thiopurine S-methyl-transferase (TPMT) polymorphisms

[1]  G. di Perri,et al.  Correlation between Thiopurine S-Methyltransferase Genotype and Adverse Events in Inflammatory Bowel Disease Patients , 2019, Medicina.

[2]  S. Jiménez-Morales,et al.  High frequency of mutant thiopurine S-methyltransferase genotypes in Mexican patients with systemic lupus erythematosus and rheumatoid arthritis , 2018, Clinical Rheumatology.

[3]  G. Goulielmos,et al.  Prevalence of thiopurine S-methyltransferase gene polymorphisms in patients with inflammatory bowel disease from the island of Crete, Greece , 2017, European journal of gastroenterology & hepatology.

[4]  A. Verbeek,et al.  Risk factors for thiopurine‐induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype , 2017, Alimentary pharmacology & therapeutics.

[5]  M. Kennedy,et al.  Allele frequencies of thiopurine S-methyltransferase (TPMT) variants in the Nigerian population , 2017 .

[6]  Shan Lu Proceedings of the 8th Workshop on Programming Languages and Operating Systems , 2015, PLOS@SOSP.

[7]  A. J. Carneiro,et al.  Thiopurine-methyltransferase variants in inflammatory bowel disease: prevalence and toxicity in Brazilian patients. , 2014, World journal of gastroenterology.

[8]  Y. Irshaid,et al.  Thiopurine S-methytransferase gene polymorphism in rheumatoid arthritis. , 2013, Archives of medical research.

[9]  R. Mantegazza,et al.  A New Thiopurine S‐Methyltransferase Haplotype Associated With Intolerance to Azathioprine , 2013, Journal of clinical pharmacology.

[10]  Simone Moreira,et al.  Toxicity of azathioprine: why and when? analysis of the prevalence of polymorphism in Joinville, SC, Brazil. , 2012, Arquivos de gastroenterologia.

[11]  M. Eandi,et al.  Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: differences in enzyme activity. , 2009, Pharmacogenomics.

[12]  S. Bombardieri,et al.  Genetic polymorphisms of thiopurine S-methyltransferase in a cohort of patients with systemic autoimmune diseases. , 2009, Clinical and Experimental Rheumatology.

[13]  J. Gisbert,et al.  Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain , 2009, European Journal of Human Genetics.

[14]  E. Sprecher,et al.  Distribution of TPMT risk alleles for thioupurine toxicity in the Israeli population , 2009, European Journal of Clinical Pharmacology.

[15]  A. Romanha,et al.  Thiopurine S-Methyltransferase (TPMT) Gene Polymorphism in Brazilian Children With Acute Lymphoblastic Leukemia: Association With Clinical and Laboratory Data , 2008, Therapeutic drug monitoring.

[16]  M. Eichelbaum,et al.  Highly multiplexed genotyping of thiopurine s-methyltransferase variants using MALD-TOF mass spectrometry: reliable genotyping in different ethnic groups. , 2008, Clinical chemistry.

[17]  J. Mate,et al.  Thiopurine Methyltransferase Activity in Spain: A Study of 14,545 Patients , 2007, Digestive Diseases and Sciences.

[18]  S. D. Pena,et al.  Pharmacogenomics in the Americas: the impact of genetic admixture. , 2006, Current drug targets.

[19]  Richard M. Weinshilboum,et al.  Pharmacogenomics: Catechol O-Methyltransferase to Thiopurine S-Methyltransferase , 2006, Cellular and Molecular Neurobiology.

[20]  M. Congia,et al.  Frequency of the thiopurine S‐methyltransferase alleles in the ancient genetic population isolate of Sardinia , 2006, Journal of clinical pharmacy and therapeutics.

[21]  R. Weinshilboum,et al.  Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions , 2006, Oncogene.

[22]  R. Cacabelos,et al.  Allelic variants of the thiopurine methyltransferase (TPMT) gene in the Colombian population. , 2003, Methods and findings in experimental and clinical pharmacology.

[23]  G. Suarez-Kurtz,et al.  Thiopurine methyltransferase phenotypes and genotypes in Brazilians. , 2003, Pharmacogenetics.

[24]  H. Corrêa,et al.  Thiopurine methyltransferase polymorphisms in a Brazilian population , 2003, The Pharmacogenomics Journal.

[25]  F. Tsai,et al.  Molecular analysis of thiopurine S-methyltransferase alleles in South-east Asian populations. , 2002, Pharmacogenetics.

[26]  M. Hiratsuka,et al.  Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population. , 2000, Mutation research.

[27]  H. McLeod,et al.  Ethnic differences in thiopurine methyltransferase pharmacogenetics: evidence for allele specificity in Caucasian and Kenyan individuals. , 1999, Pharmacogenetics.

[28]  D. Collier,et al.  The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations. , 1999, Pharmacogenetics.

[29]  H. McLeod,et al.  Thiopurine methyltransferase alleles in British and Ghanaian populations. , 1999, Human molecular genetics.

[30]  Ching-Hon Pui,et al.  Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance , 1997, Annals of Internal Medicine.