An unappreciated role for RNA surveillance

[1]  C. Gooding,et al.  Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. , 2004, Molecular cell.

[2]  Jennifer Daub,et al.  Expressed sequence tags: medium-throughput protocols. , 2004, Methods in molecular biology.

[3]  D. Black.  Mechanisms of alternative pre-messenger RNA splicing. , 2003, Annual review of biochemistry.

[4]  H. You,et al.  Transcriptional mutagenesis induced by uracil and 8-oxoguanine in Escherichia coli. , 2003, Molecular cell.

[5]  H. Firth,et al.  Allelic variation in normal human FBN1 expression in a family with Marfan syndrome: a potential modifier of phenotype? , 2003, Human molecular genetics.

[6]  P. Bork,et al.  Nonsense‐mediated mRNA decay in Drosophila:at the intersection of the yeast and mammalian pathways , 2003, The EMBO journal.

[7]  Steven E. Brenner,et al.  Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes , 2003, ISMB.

[8]  Christopher J. Lee,et al.  Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss , 2003, Nature Genetics.

[9]  R. Breathnach,et al.  TIA-1 or TIAR Is Required for DT40 Cell Viability* , 2003, The Journal of Biological Chemistry.

[10]  P. Calvas,et al.  Screening for PAX6 gene mutations is consistent with haploinsufficiency as the main mechanism leading to various ocular defects , 2003, European Journal of Human Genetics.

[11]  E. Schuetz,et al.  Nonsense mediated decay downregulates conserved alternatively spliced ABCC4 transcripts bearing nonsense codons. , 2003, Human molecular genetics.

[12]  Maria Jesus Martin,et al.  The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 , 2003, Nucleic Acids Res..

[13]  B. Alberts,et al.  Molecular Biology of the Cell 4th edition , 2007 .

[14]  S. Brenner,et al.  Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[15]  Paul Richardson,et al.  The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins , 2002, Science.

[16]  David States,et al.  Selecting for functional alternative splices in ESTs. , 2002, Genome research.

[17]  H. Le Hir,et al.  5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. , 2002, Genes & development.

[18]  A. Telser.  Molecular Biology of the Cell, 4th Edition , 2002 .

[19]  J. Lykke-Andersen,et al.  mRNA surveillance: the perfect persist. , 2002, Journal of cell science.

[20]  G. Dreyfuss,et al.  Translation Is Required to Remove Y14 from mRNAs in the Cytoplasm , 2002, Current Biology.

[21]  O. Mühlemann,et al.  Intranuclear degradation of nonsense codon‐containing mRNA , 2002, EMBO reports.

[22]  L. Maquat.  Nonsense-mediated mRNA decay , 2002, Current Biology.

[23]  Christopher J. Lee,et al.  A genomic view of alternative splicing , 2002, Nature Genetics.

[24]  D. Church,et al.  Spidey: a tool for mRNA-to-genomic alignments. , 2001, Genome research.

[25]  Margot Thome,et al.  Regulation of lymphocyte proliferation and death by flip , 2001, Nature Reviews Immunology.

[26]  B. Graveley,et al.  Alternative splicing of the Drosophila Dscam pre-mRNA is both temporally and spatially regulated. , 2001, Genetics.

[27]  J. Steitz,et al.  Communication of the Position of Exon-Exon Junctions to the mRNA Surveillance Machinery by the Protein RNPS1 , 2001, Science.

[28]  L. Maquat,et al.  Evidence for a Pioneer Round of mRNA Translation mRNAs Subject to Nonsense-Mediated Decay in Mammalian Cells Are Bound by CBP80 and CBP20 , 2001, Cell.

[29]  H. Le Hir,et al.  The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense‐mediated mRNA decay , 2001, The EMBO journal.

[30]  O. Hankinson,et al.  Loss of cyp1a1 messenger rna expression due to nonsense-mediated decay. , 2001, Molecular pharmacology.

[31]  C. Bogardus,et al.  Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms. , 2001, Molecular genetics and metabolism.

[32]  H. Dietz,et al.  A strategy for disease gene identification through nonsense-mediated mRNA decay inhibition , 2001, Nature Biotechnology.

[33]  A Sureau,et al.  SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs , 2001, The EMBO journal.

[34]  J. Mendell,et al.  Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. , 2001, Human molecular genetics.

[35]  Donna R. Maglott,et al.  RefSeq and LocusLink: NCBI gene-centered resources , 2001, Nucleic Acids Res..

[36]  International Human Genome Sequencing Consortium.  Initial sequencing and analysis of the human genome , 2001, Nature.

[37]  H. Le Hir,et al.  The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions , 2000, The EMBO journal.

[38]  Tom H. Lindner,et al.  Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus , 2000, Nature Genetics.

[39]  C. Bogardus,et al.  A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. , 2000, The Journal of clinical investigation.

[40]  G. Landreth,et al.  Biochemical characterization and localization of the dual specificity kinase CLK1. , 2000, Journal of cell science.

[41]  Q. Mitrovich,et al.  Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans. , 2000, Genes & development.

[42]  Roderic Guigó,et al.  Gff2ps: Visualizing Genomic Annotations , 2000, Bioinform..

[43]  H. Le Hir,et al.  Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions. , 2000, Genes & development.

[44]  M. Ruiz-Echevarría,et al.  The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay. , 2000, Molecular cell.

[45]  M. Culbertson,et al.  Yeast Upf Proteins Required for RNA Surveillance Affect Global Expression of the Yeast Transcriptome , 1999, Molecular and Cellular Biology.

[46]  G. M. Wilson,et al.  Regulation of AUF1 Expression via Conserved Alternatively Spliced Elements in the 3′ Untranslated Region , 1999, Molecular and Cellular Biology.

[47]  H. Dietz,et al.  Nonsense-mediated mRNA decay in health and disease. , 1999, Human molecular genetics.

[48]  P. Anderson,et al.  mRNA surveillance mitigates genetic dominance in Caenorhabditis elegans , 1998, Molecular and General Genetics MGG.

[49]  J. Bell,et al.  The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing. , 1998, Experimental cell research.

[50]  L. Maquat,et al.  A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance. , 1998, Trends in biochemical sciences.

[51]  Shulin Li,et al.  Nonsense surveillance in lymphocytes? , 1998, Immunity.

[52]  J. Bell,et al.  In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase , 1997, Molecular and cellular biology.

[53]  M B Roth,et al.  smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[54]  J. Bell,et al.  LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[55]  J. Adachi,et al.  MOLPHY version 2.3 : programs for molecular phylogenetics based on maximum likelihood , 1996 .

[56]  M. Carter,et al.  A Regulatory Mechanism That Detects Premature Nonsense Codons in T-cell Receptor Transcripts in Vivo Is Reversed by Protein Synthesis Inhibitors in Vitro* , 1995, The Journal of Biological Chemistry.

[57]  J. Hanes,et al.  Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases. , 1994, Journal of molecular biology.

[58]  J. Thompson,et al.  CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. , 1994, Nucleic acids research.

[59]  M. Boguski,et al.  dbEST — database for “expressed sequence tags” , 1993, Nature Genetics.

[60]  S. Peltz,et al.  The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon. , 1991, Genes & development.

[61]  E. Myers,et al.  Basic local alignment search tool. , 1990, Journal of molecular biology.

[62]  E. Myers,et al.  Approximate matching of regular expressions. , 1989, Bulletin of mathematical biology.

[63]  L. Maquat,et al.  mRNA-deficint β°-thaladssemia results from a single nucleotide deletion , 1982 .

[64]  L. Maquat,et al.  mRNA-deficient beta o-thalassemia results from a single nucleotide deletion. , 1982, Nucleic acids research.