Saturation Editing of Genomic Regions by Multiplex Homology-Directed Repair
暂无分享,去创建一个
Jay Shendure | Evan A. Boyle | J. Shendure | Ronald J. Hause | Gregory M. Findlay | E. Boyle | J. Klein | Jason Klein
[1] J. Doudna,et al. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , 2012, Science.
[2] Jac A. Nickoloff,et al. Gene Conversion Tracts from Double-Strand Break Repair in Mammalian Cells , 1998, Molecular and Cellular Biology.
[3] C. Barbas,et al. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. , 2013, Trends in biotechnology.
[4] P. Radivojac,et al. MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing , 2014, Genome Biology.
[5] S. Shuman,et al. Structure–function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase , 2005, Nucleic acids research.
[6] J. Wells,et al. High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. , 1989, Science.
[7] James E. DiCarlo,et al. RNA-Guided Human Genome Engineering via Cas9 , 2013, Science.
[8] S. Henikoff,et al. Amino acid substitution matrices from protein blocks. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[9] Jeffry D. Sander,et al. CRISPR-Cas systems for editing, regulating and targeting genomes , 2014, Nature Biotechnology.
[10] Jay Shendure,et al. High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis , 2009, Nature Biotechnology.
[11] Eli J. Fine,et al. DNA targeting specificity of RNA-guided Cas9 nucleases , 2013, Nature Biotechnology.
[12] J. Kinney,et al. Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence , 2010, Proceedings of the National Academy of Sciences.
[13] Jeffry D Sander,et al. FLAsH assembly of TALeNs for high-throughput genome editing , 2022 .
[14] Jingyue Ju,et al. Quantitative evaluation of all hexamers as exonic splicing elements. , 2011, Genome research.
[15] R. Myers,et al. Fine structure genetic analysis of a beta-globin promoter. , 1986, Science.
[16] Dana Carroll,et al. Genome engineering with targetable nucleases. , 2014, Annual review of biochemistry.
[17] E. Mcwhinnie,et al. DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells. , 2014, Nature chemical biology.
[18] P. Bork,et al. A method and server for predicting damaging missense mutations , 2010, Nature Methods.
[19] Rudolf Jaenisch,et al. One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering , 2013, Cell.
[20] Le Cong,et al. Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.
[21] J. Shendure,et al. A general framework for estimating the relative pathogenicity of human genetic variants , 2014, Nature Genetics.
[22] D. Baker,et al. High Resolution Mapping of Protein Sequence–Function Relationships , 2010, Nature Methods.
[23] C.-C. Jay Kuo,et al. GC content around splice sites affects splicing through pre-mRNA secondary structures , 2011, BMC Genomics.
[24] Markus Seiler,et al. The transience of transient overexpression , 2013, Nature Methods.
[25] Thuy D. Vo,et al. Transient cold shock enhances zinc-finger nuclease–mediated gene disruption , 2010, Nature Methods.
[26] Shondra M Pruett-Miller,et al. High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases , 2011, Nature Methods.
[27] G M Lenoir,et al. A BRCA1 nonsense mutation causes exon skipping. , 1998, American journal of human genetics.
[28] Joseph B Hiatt,et al. Massively parallel functional dissection of mammalian enhancers in vivo , 2012, Nature Biotechnology.
[29] Jiajie Zhang,et al. PEAR: a fast and accurate Illumina Paired-End reAd mergeR , 2013, Bioinform..
[30] Elisa Goina,et al. Binding of DAZAP1 and hnRNPA1/A2 to an Exonic Splicing Silencer in a Natural BRCA1 Exon 18 Mutant , 2008, Molecular and Cellular Biology.
[31] E. Lander,et al. Genetic Screens in Human Cells Using the CRISPR-Cas9 System , 2013, Science.
[32] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[33] D Botstein,et al. Strategies and applications of in vitro mutagenesis. , 1985, Science.
[34] Feng Zhang,et al. Genome engineering using CRISPR-Cas9 system. , 2015, Methods in molecular biology.
[35] Carla P. Guimarães,et al. Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens , 2009, Science.