Tetracycline resistance in Moraxella (Branhamella) catarrhalis: demonstration of two clonal outbreaks by using pulsed-field gel electrophoresis

Two tetracycline-resistant (Tcr) Moraxella (Branhamella) catarrhalis strains from England were compared with two previously characterized Tcr Texas strains. Both pairs carried the Tet B determinant, which was nontransferable. Pulsed-field gel electrophoresis of their genomic DNA restriction fragments demonstrated that the strains from the same area were identical (clonal); however, the Texas and English strains differed from each other.

[1]  S. Levy,et al.  Transposon Tn10-like tetracycline resistance determinants in Haemophilus parainfluenzae , 1984, Journal of bacteriology.

[2]  R. Spencer,et al.  In-vitro activity of roxithromycin against Branhamella catarrhalis. , 1990, The Journal of antimicrobial chemotherapy.

[3]  M. Roberts,et al.  Cloning and characterization of tetM gene from a Ureaplasma urealyticum strain , 1987, Antimicrobial Agents and Chemotherapy.

[4]  R. Wallace,,et al.  Genetic basis of tetracycline resistance in Moraxella (Branhamella) catarrhalis , 1990, Antimicrobial Agents and Chemotherapy.

[5]  B. Davies,et al.  The epidemiology of respiratory tract pathogens in southern Netherlands. , 1988, The European respiratory journal.

[6]  S. Levy,et al.  Heterogeneity of tetracycline resistance determinants. , 1980, Plasmid.

[7]  R. Gómez-Lus,et al.  Enzymatic modification of aminoglycoside antibiotics by Branhamella catarrhalis carrying an R factor. , 1987, Drugs under experimental and clinical research.

[8]  S. Levy,et al.  Homogeneity of transferable tetracycline-resistance determinants in Haemophilus species. , 1984, The Journal of infectious diseases.

[9]  S. Levy,et al.  Frequency of tetracycline resistance determinant classes among lactose-fermenting coliforms , 1983, Antimicrobial Agents and Chemotherapy.

[10]  P. H. Roy,et al.  Characterization of a plasmid isolated from Branhamella catarrhalis and detection of plasmid sequences within the genome of a B. catarrhalis strain. , 1988, Plasmid.

[11]  R. Wallace,,et al.  Tetracycline and erythromycin resistance among clinical isolates of Branhamella catarrhalis , 1989, Antimicrobial Agents and Chemotherapy.

[12]  R. Wallace,,et al.  BRO beta-lactamases of Branhamella catarrhalis and Moraxella subgenus Moraxella, including evidence for chromosomal beta-lactamase transfer by conjugation in B. catarrhalis, M. nonliquefaciens, and M. lacunata , 1989, Antimicrobial Agents and Chemotherapy.

[13]  X. T. Zheng,et al.  Beta-lactamase-producing Branhamella in Beijing, China. , 1988, The Pediatric infectious disease journal.

[14]  S. Hillier,et al.  Genetic basis of tetracycline resistance in urogenital bacteria , 1990, Antimicrobial Agents and Chemotherapy.

[15]  J. Knapp,et al.  Host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from Neisseria gonorrhoeae and related species , 1988, Antimicrobial Agents and Chemotherapy.