Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly

[1]  R. Bernabei,et al.  Mitochondrial dynamics signaling is shifted toward fusion in muscles of very old hip-fractured patients: Results from the Sarcopenia in HIp FracTure (SHIFT) exploratory study , 2017, Experimental Gerontology.

[2]  J. Praestgaard,et al.  Treatment of Sarcopenia with Bimagrumab: Results from a Phase II, Randomized, Controlled, Proof‐of‐Concept Study , 2017, Journal of the American Geriatrics Society.

[3]  S. Studenski,et al.  Muscle strength mediates the relationship between mitochondrial energetics and walking performance , 2017, Aging cell.

[4]  R. Fielding,et al.  Efficacy of a novel formulation of L-Carnitine, creatine, and leucine on lean body mass and functional muscle strength in healthy older adults: a randomized, double-blind placebo-controlled study , 2017, Nutrition & Metabolism.

[5]  N. Larsson,et al.  Mammalian Mitochondria and Aging: An Update. , 2017, Cell metabolism.

[6]  T. Travison,et al.  Effects of Testosterone Supplementation for 3 Years on Muscle Performance and Physical Function in Older Men , 2016, The Journal of clinical endocrinology and metabolism.

[7]  M. Garcia-Conesa,et al.  Urolithins, the rescue of "old" metabolites to understand a "new" concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status. , 2017, Molecular nutrition & food research.

[8]  N. Rajab,et al.  Efficacy of L-carnitine supplementation on frailty status and its biomarkers, nutritional status, and physical and cognitive function among prefrail older adults: a double-blind, randomized, placebo-controlled clinical trial , 2016, Clinical interventions in aging.

[9]  J. Auwerx,et al.  NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation , 2016, Science Translational Medicine.

[10]  Evan G. Williams,et al.  Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents , 2016, Nature Medicine.

[11]  R. Bernabei,et al.  Association between myocyte quality control signaling and sarcopenia in old hip-fractured patients: Results from the Sarcopenia in HIp FracTure (SHIFT) exploratory study , 2016, Experimental Gerontology.

[12]  B. Bogen,et al.  Identifying low muscle mass in patients with hip fracture: Validation of bioelectrical impedance analysis and anthropometry compared to dual energy X-ray absorptiometry , 2016, The journal of nutrition, health & aging.

[13]  Nancy W Glynn,et al.  Skeletal Muscle Mitochondrial Function and Fatigability in Older Adults. , 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

[14]  Kelly J. Bower,et al.  Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study , 2015, PloS one.

[15]  H. Yanai Nutrition for Sarcopenia , 2015, Journal of clinical medicine research.

[16]  R. Kreis,et al.  Exercise efficiency relates with mitochondrial content and function in older adults , 2015, Physiological reports.

[17]  Effect of L-carnitine on exercise performance in patients with mitochondrial myopathy , 2015, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[18]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[19]  O. Cauli,et al.  Clinical features of prefrail older individuals and emerging peripheral biomarkers: a systematic review. , 2014, Archives of gerontology and geriatrics.

[20]  J. Auwerx,et al.  Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3 , 2014, EMBO molecular medicine.

[21]  R. Kreis,et al.  Skeletal muscle mitochondria in the elderly: effects of physical fitness and exercise training. , 2014, The Journal of clinical endocrinology and metabolism.

[22]  G. Perkins,et al.  (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. , 2013, International journal of cardiology.

[23]  A. Csiszar,et al.  Mitochondria in Cardiovascular Physiology and Disease Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease : from mechanisms to therapeutics , 2013 .

[24]  W. Poewe,et al.  Bioenergetics of the Calf Muscle in Friedreich Ataxia Patients Measured by 31P-MRS Before and After Treatment with Recombinant Human Erythropoietin , 2013, PloS one.

[25]  Robert W. Taylor,et al.  Mitochondrial DNA deletions in muscle satellite cells: implications for therapies , 2013, Human molecular genetics.

[26]  Manuel Serrano,et al.  The Hallmarks of Aging , 2013, Cell.

[27]  G. Pasinetti,et al.  Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models , 2013, Neurobiology of Aging.

[28]  D. Papanicolaou,et al.  A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia , 2013, The journal of nutrition, health & aging.

[29]  L. Ferrucci,et al.  Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[30]  M. Hopman,et al.  Expression of genes involved in fatty acid transport and insulin signaling is altered by physical inactivity and exercise training in human skeletal muscle. , 2012, American journal of physiology. Endocrinology and metabolism.

[31]  T. Manini,et al.  The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high‐ and low‐functioning elderly individuals , 2012, Aging cell.

[32]  R. Whiteley,et al.  Correlation of isokinetic and novel hand-held dynamometry measures of knee flexion and extension strength testing. , 2012, Journal of science and medicine in sport.

[33]  A. Rissanen,et al.  Agreement of bioelectrical impedance with dual-energy X-ray absorptiometry and MRI to estimate changes in body fat, skeletal muscle and visceral fat during a 12-month weight loss intervention , 2012, British Journal of Nutrition.

[34]  J. Auwerx,et al.  The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. , 2012, Cell metabolism.

[35]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[36]  Ian R. Lanza,et al.  Measurement of human skeletal muscle oxidative capacity by 31P‐MR spectroscopy: A cross‐validation with in vitro measurements , 2011, Journal of magnetic resonance imaging : JMRI.

[37]  R. Engelbert,et al.  Reliability of maximal isometric knee strength testing with modified hand-held dynamometry in patients awaiting total knee arthroplasty: useful in research and individual patient settings? A reliability study , 2011, BMC musculoskeletal disorders.

[38]  D. Green,et al.  Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging , 2011, Science.

[39]  J. Dalton,et al.  The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial , 2011, Journal of cachexia, sarcopenia and muscle.

[40]  M. Tarnopolsky,et al.  Suction‐modified Bergström muscle biopsy technique: Experience with 13,500 procedures , 2011, Muscle & nerve.

[41]  L. Ngo,et al.  Evaluation of skeletal muscle during calf exercise by 31‐phosphorus magnetic resonance spectroscopy in patients on statin medications , 2011, Muscle & nerve.

[42]  H. Pilegaard,et al.  Endurance exercise induces mRNA expression of oxidative enzymes in human skeletal muscle late in recovery , 2010, Scandinavian journal of medicine & science in sports.

[43]  Robert W. Williams,et al.  Metabolic Networks of Longevity , 2010, Cell.

[44]  J. Baeyens,et al.  Sarcopenia: European consensus on definition and diagnosis , 2010, Age and ageing.

[45]  Peter Dalgaard,et al.  R Development Core Team (2010): R: A language and environment for statistical computing , 2010 .

[46]  J. Baeyens,et al.  European working group on sarcopenia in older people. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people , 2010 .

[47]  R. Baumgartner,et al.  Mitochondrial function in physically active elders with sarcopenia , 2009, Mechanisms of Ageing and Development.

[48]  N. M. van den Broek,et al.  Intersubject differences in the effect of acidosis on phosphocreatine recovery kinetics in muscle after exercise are due to differences in proton efflux rates. , 2007, American journal of physiology. Cell physiology.

[49]  Alan Hubbard,et al.  Resistance Exercise Reverses Aging in Human Skeletal Muscle , 2007, PloS one.

[50]  S. Hayek,et al.  Effects of aerobic training on gene expression in skeletal muscle of elderly men. , 2005, Medicine and science in sports and exercise.

[51]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[52]  K. Nair,et al.  Decline in skeletal muscle mitochondrial function with aging in humans. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[53]  R. Kreis,et al.  Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes. , 2003, Physiological genomics.

[54]  B. Ainsworth,et al.  International physical activity questionnaire: 12-country reliability and validity. , 2003, Medicine and science in sports and exercise.

[55]  K. Manton,et al.  Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[56]  L. Fried,et al.  Frailty in older adults: evidence for a phenotype. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[57]  P. Neufer,et al.  Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. , 2000, American journal of physiology. Endocrinology and metabolism.

[58]  R. Ross,et al.  Estimation of skeletal muscle mass by bioelectrical impedance analysis. , 2000, Journal of applied physiology.

[59]  I. Pipinos,et al.  Phosphorus 31 nuclear magnetic resonance spectroscopy suggests a mitochondrial defect in claudicating skeletal muscle. , 2000, Journal of vascular surgery.

[60]  Suzanne G. Leveille,et al.  Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. , 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

[61]  G. Capuani,et al.  31Phosphorus magnetic resonance spectroscopy to evaluate medical therapy efficacy in peripheral arterial disease. A pilot study. , 1999, Panminerva medica.

[62]  L. Ferrucci,et al.  A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. , 1994, Journal of gerontology.

[63]  K. Johnson An Update. , 1984, Journal of food protection.

[64]  Sung Gyoo Park Medicine and Science in Sports and Exercise , 1981 .

[65]  Wright Bm A simple mechanical ataxia-meter. , 1971 .

[66]  B. M. Wright A simple mechanical ataxia-meter. , 1971, The Journal of physiology.