The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis

[1]  L. Luo,et al.  Splinkerette PCR for Mapping Transposable Elements in Drosophila , 2010, PloS one.

[2]  L. Luo,et al.  Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain , 2010, Development.

[3]  L. Luo,et al.  Leucine-Rich Repeat Transmembrane Proteins Instruct Discrete Dendrite Targeting in an Olfactory Map , 2009, Nature Neuroscience.

[4]  C. Bakal,et al.  The Twin Spot Generator for differential Drosophila lineage analysis , 2009, Nature Methods.

[5]  Tzumin Lee,et al.  Twin-Spot MARCM to reveal developmental origin and identity of neurons , 2009, Nature Neuroscience.

[6]  L. Luo,et al.  MicroRNA Processing Pathway Regulates Olfactory Neuron Morphogenesis , 2008, Current Biology.

[7]  Kei Ito,et al.  Clonal analysis of Drosophila antennal lobe neurons: diverse neuronal architectures in the lateral neuroblast lineage , 2008, Development.

[8]  G. Rubin,et al.  Tools for neuroanatomy and neurogenetics in Drosophila , 2008, Proceedings of the National Academy of Sciences.

[9]  N. Perrimon,et al.  Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes , 2008, Nature Genetics.

[10]  K. Svoboda,et al.  Genetic Dissection of Neural Circuits , 2008, Neuron.

[11]  L. Luo.  Fly MARCM and mouse MADM: Genetic methods of labeling and manipulating single neurons , 2007, Brain Research Reviews.

[12]  L. Luo,et al.  A global double‐fluorescent Cre reporter mouse , 2007, Genesis.

[13]  B. Dickson,et al.  A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila , 2007, Nature.

[14]  L. Luo,et al.  Comprehensive Maps of Drosophila Higher Olfactory Centers: Spatially Segregated Fruit and Pheromone Representation , 2007, Cell.

[15]  R. Maeda,et al.  An optimized transgenesis system for Drosophila using germ-line-specific φC31 integrases , 2007, Proceedings of the National Academy of Sciences.

[16]  C. S. Raymond,et al.  High-Efficiency FLP and ΦC31 Site-Specific Recombination in Mammalian Cells , 2007, PloS one.

[17]  Haojiang Luan,et al.  Refined Spatial Manipulation of Neuronal Function by Combinatorial Restriction of Transgene Expression , 2006, Neuron.

[18]  Sen-Lin Lai,et al.  Genetic mosaic with dual binary transcriptional systems in Drosophila , 2006, Nature Neuroscience.

[19]  Liqun Luo,et al.  Wiring Stability of the Adult Drosophila Olfactory Circuit after Lesion , 2006, The Journal of Neuroscience.

[20]  L. Luo,et al.  A protocol for dissecting Drosophila melanogaster brains for live imaging or immunostaining , 2006, Nature Protocols.

[21]  Daisuke Yamamoto,et al.  Fruitless specifies sexually dimorphic neural circuitry in the Drosophila brain , 2005, Nature.

[22]  S. Small,et al.  Site-specific transgenesis by Cre-mediated recombination in Drosophila , 2005, Nature Methods.

[23]  Devanand S. Manoli,et al.  Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour , 2005, Nature.

[24]  D. Kvitsiani,et al.  Neural Circuitry that Governs Drosophila Male Courtship Behavior , 2005, Cell.

[25]  Barry J. Dickson,et al.  fruitless Splicing Specifies Male Courtship Behavior in Drosophila , 2005, Cell.

[26]  L. Luo,et al.  Mosaic Analysis with Double Markers in Mice , 2005, Cell.

[27]  L. Luo,et al.  Developmentally programmed remodeling of the Drosophila olfactory circuit , 2005, Development.

[28]  Leslie B. Vosshall,et al.  Or83b Encodes a Broadly Expressed Odorant Receptor Essential for Drosophila Olfaction , 2004, Neuron.

[29]  Liqun Luo,et al.  Olfactory receptor neuron axon targeting: intrinsic transcriptional control and hierarchical interactions , 2004, Nature Neuroscience.

[30]  Michele P Calos,et al.  Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. , 2004, Genetics.

[31]  J. Edwards,et al.  Postembryonic brain development in the monarch butterfly,Danaus plexippus plexippus L. , 1969, Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen.

[32]  J. Edwards,et al.  Postembryonic brain development in the monarch butterfly,Danaus plexippus plexippus, L. , 1969, Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen.

[33]  Ronald L. Davis,et al.  Spatiotemporal Rescue of Memory Dysfunction in Drosophila , 2003, Science.

[34]  M. Suster,et al.  Targeted expression of tetanus toxin reveals sets of neurons involved in larval locomotion in Drosophila. , 2003, Journal of neurobiology.

[35]  Gregory S.X.E. Jefferis,et al.  From Lineage to Wiring Specificity POU Domain Transcription Factors Control Precise Connections of Drosophila Olfactory Projection Neurons , 2003, Cell.

[36]  Shigeo Hayashi,et al.  GETDB, a database compiling expression patterns and molecular locations of a collection of gal4 enhancer traps , 2002, Genesis.

[37]  Richard Axel,et al.  Spatial Representation of the Glomerular Map in the Drosophila Protocerebrum , 2002, Cell.

[38]  L. Luo,et al.  Representation of the Glomerular Olfactory Map in the Drosophila Brain , 2002, Cell.

[39]  K. Basler,et al.  A screen for genes expressed in Drosophila imaginal discs. , 2002, The International journal of developmental biology.

[40]  Liqun Luo,et al.  Target neuron prespecification in the olfactory map of Drosophila , 2001, Nature.

[41]  C. Potter,et al.  Drosophila Tsc1 Functions with Tsc2 to Antagonize Insulin Signaling in Regulating Cell Growth, Cell Proliferation, and Organ Size , 2001, Cell.

[42]  B. Dickson,et al.  The Drosophila Tuberous Sclerosis Complex Gene Homologs Restrict Cell Growth and Cell Proliferation , 2001, Cell.

[43]  T. Kitamoto.  Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neurons. , 2001, Journal of neurobiology.

[44]  G. Rubin,et al.  gigas , a Drosophila Homolog of Tuberous Sclerosis Gene Product-2, Regulates the Cell Cycle , 1999, Cell.

[45]  Andrew P. McMahon,et al.  Sonic hedgehog Regulates Proliferation and Inhibits Differentiation of CNS Precursor Cells , 1999, The Journal of Neuroscience.

[46]  L. Luo,et al.  Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast. , 1999, Development.

[47]  Liqun Luo,et al.  Mosaic Analysis with a Repressible Cell Marker for Studies of Gene Function in Neuronal Morphogenesis , 1999, Neuron.

[48]  W. A. Johnson,et al.  The Odor Specificities of a Subset of Olfactory Receptor Neurons Are Governed by Acj6, a POU-Domain Transcription Factor , 1999, Neuron.

[49]  G. Rubin,et al.  Systematic gain-of-function genetics in Drosophila. , 1998, Development.

[50]  R. Stocker,et al.  Neuroblast ablation in Drosophila P[GAL4] lines reveals origins of olfactory interneurons. , 1997, Journal of neurobiology.

[51]  N. Perrimon,et al.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. , 1993, Development.

[52]  G. Rubin,et al.  Analysis of genetic mosaics in developing and adult Drosophila tissues. , 1993, Development.

[53]  M. Gossen,et al.  Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[54]  P. Leder,et al.  Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[55]  M. Case,et al.  The Wilhelmine E. Key 1989 invitational lecture. Organization and regulation of the qa (quinic acid) genes in Neurospora crassa and other fungi. , 1991, The Journal of heredity.

[56]  S. Lindquist,et al.  The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome , 1989, Cell.

[57]  Tom Maniatis,et al.  GAL4 activates transcription in Drosophila , 1988, Nature.

[58]  N. Giles,et al.  Expression of qa-1F activator protein: identification of upstream binding sites in the qa gene cluster and localization of the DNA-binding domain , 1987, Molecular and cellular biology.

[59]  L. Huiet,et al.  The qa repressor gene of Neurospora crassa: wild-type and mutant nucleotide sequences. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[60]  P. Bryant,et al.  Intrinsic and Extrinsic Control of Growth in Developing Organs , 1984, The Quarterly Review of Biology.

[61]  G. Rubin,et al.  Transposition of cloned P elements into Drosophila germ line chromosomes. , 1982, Science.

[62]  M. Schweizer,et al.  Genetic organization and transcriptional regulation in the qa gene cluster of Neurospora crassa. , 1981, Proceedings of the National Academy of Sciences of the United States of America.