The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature.
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[1] J. Loscalzo,et al. Epigenetic Modifications: Basic Mechanisms and Role in Cardiovascular Disease (2013 Grover Conference Series) , 2014, Pulmonary circulation.
[2] P. Holvoet,et al. MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] M. Blüher,et al. An inflammatory micro-environment promotes human adipocyte apoptosis , 2011, Molecular and Cellular Endocrinology.
[4] M. Muñoz-Torres,et al. Osteocalcin and atherosclerosis: a complex relationship. , 2011, Diabetes research and clinical practice.
[5] S. Lorkowski,et al. Improved protocol for efficient nonviral transfection of premature THP-1 macrophages. , 2011, Cold Spring Harbor protocols.
[6] K. Zen,et al. Role of MicroRNA-214–Targeting Phosphatase and Tensin Homolog in Advanced Glycation End Product-Induced Apoptosis Delay in Monocytes , 2011, The Journal of Immunology.
[7] V. Kalra,et al. Endothelin-1–Induced Macrophage Inflammatory Protein-1β Expression in Monocytic Cells Involves Hypoxia-Inducible Factor-1α and AP-1 and Is Negatively Regulated by microRNA-195 , 2010, The Journal of Immunology.
[8] J. Ordovás,et al. Epigenetics and cardiovascular disease , 2010, Nature Reviews Cardiology.
[9] D. Bruemmer,et al. Deficiency of the NR4A Orphan Nuclear Receptor NOR1 Decreases Monocyte Adhesion and Atherosclerosis , 2010, Circulation research.
[10] K. Gee,et al. Interleukin-27 Induces a STAT1/3- and NF-κB-dependent Proinflammatory Cytokine Profile in Human Monocytes* , 2010, The Journal of Biological Chemistry.
[11] K. Vickers,et al. MicroRNAs in atherosclerosis and lipoprotein metabolism , 2010, Current opinion in endocrinology, diabetes, and obesity.
[12] Marc Daigneault,et al. The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages , 2010, PloS one.
[13] Satoki Nakamura,et al. Reduction of Raf Kinase Inhibitor Protein Expression by Bcr-Abl Contributes to Chronic Myelogenous Leukemia Proliferation* , 2009, The Journal of Biological Chemistry.
[14] M. Raftery,et al. Leukocyte Ig-like Receptor B4 (LILRB4) Is a Potent Inhibitor of FcγRI-mediated Monocyte Activation via Dephosphorylation of Multiple Kinases , 2009, The Journal of Biological Chemistry.
[15] E. Savolainen,et al. The expression of human resistin in different leucocyte lineages is modulated by LPS and TNFα , 2009, Regulatory Peptides.
[16] Stefan Lorkowski,et al. Efficient non-viral transfection of THP-1 cells. , 2009, Journal of immunological methods.
[17] R. Natarajan,et al. Distinct Roles of Heterogeneous Nuclear Ribonuclear Protein K and microRNA-16 in Cyclooxygenase-2 RNA Stability Induced by S100b, a Ligand of the Receptor for Advanced Glycation End Products*♦ , 2008, Journal of Biological Chemistry.
[18] Z. Qin,et al. Newly developed angiotensin II-infused experimental models in vascular biology , 2008, Regulatory Peptides.
[19] H. Bujo,et al. Macrophages regulate tumor necrosis factor-α expression in adipocytes through the secretion of matrix metalloproteinase-3 , 2008, International Journal of Obesity.
[20] A. Sorisky,et al. The antiadipogenic effect of macrophage-conditioned medium depends on ERK1/2 activation. , 2008, Metabolism: clinical and experimental.
[21] Aadel A. Chaudhuri,et al. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder , 2008, The Journal of experimental medicine.
[22] M. Hayden,et al. Spontaneous Atherosclerosis in Aged Lipoprotein Lipase–Deficient Mice With Severe Hypertriglyceridemia on a Normal Chow Diet , 2008, Circulation research.
[23] P. Libby,et al. Adiponectin Inhibits the Production of CXC Receptor 3 Chemokine Ligands in Macrophages and Reduces T-Lymphocyte Recruitment in Atherogenesis , 2008, Circulation research.
[24] E. Degerman,et al. Perilipin and adipophilin expression in lipid loaded macrophages. , 2007, Biochemical and biophysical research communications.
[25] J. Freedman,et al. Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells , 2007, Transfusion.
[26] T. Stulnig,et al. Adipose tissue macrophages. , 2007, Immunology letters.
[27] F. Ohsuzu,et al. ATP-Binding Cassette Transporter A1 Gene Transcription Is Downregulated by Activator Protein 2&agr;: Doxazosin Inhibits Activator Protein 2&agr; and Increases High-Density Lipoprotein Biogenesis Independent of &agr;1-Adrenoceptor Blockade , 2007 .
[28] N. Dogra,et al. Leishmania major Abrogates Gamma Interferon-Induced Gene Expression in Human Macrophages from a Global Perspective , 2007, Infection and Immunity.
[29] A. Ross,et al. Retinoic Acid Regulates CD1d Gene Expression at the Transcriptional Level in Human and Rodent Monocytic Cells , 2007, Experimental biology and medicine.
[30] H. Makino,et al. Changes of gene expression profiles in macrophages stimulated by angiotensin II — Angiotensin II induces MCP-2 through AT1-receptor , 2007, Journal of the renin-angiotensin-aldosterone system : JRAAS.
[31] John S. Hill,et al. Suppression of endothelial or lipoprotein lipase in THP-1 macrophages attenuates proinflammatory cytokine secretions⃞ Published, JLR Papers in Press, November 8, 2006. , 2007, Journal of Lipid Research.
[32] David Baltimore,et al. MicroRNA-155 is induced during the macrophage inflammatory response , 2007, Proceedings of the National Academy of Sciences.
[33] N. Perkins,et al. Transcriptional profiling of the LPS induced NF-κB response in macrophages , 2007, BMC Immunology.
[34] F. Paliogianni,et al. Expression of Immunomodulatory Genes in Human Monocytes Induced by Voriconazole in the Presence of Aspergillus fumigatus , 2006, Antimicrobial Agents and Chemotherapy.
[35] S. Sreevatsan,et al. Comparative Transcriptional Analysis of Human Macrophages Exposed to Animal and Human Isolates of Mycobacterium avium Subspecies paratuberculosis with Diverse Genotypes , 2006, Infection and Immunity.
[36] D. States,et al. A Dominant Function of IKK/NF-κB Signaling in Global Lipopolysaccharide-induced Gene Expression* , 2006, Journal of Biological Chemistry.
[37] D. Ray,et al. Human Macrophage Migration Inhibitory Factor , 2006, Journal of Biological Chemistry.
[38] Ali Ahmad,et al. Monocyte Differentiation Up-regulates the Expression of the Lysosomal Sialidase, Neu1, and Triggers Its Targeting to the Plasma Membrane via Major Histocompatibility Complex Class II-positive Compartments* , 2006, Journal of Biological Chemistry.
[39] P. Libby,et al. Apolipoprotein CIII Induces Expression of Vascular Cell Adhesion Molecule-1 in Vascular Endothelial Cells and Increases Adhesion of Monocytic Cells , 2006, Circulation.
[40] D. Baltimore,et al. NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses , 2006, Proceedings of the National Academy of Sciences.
[41] J. Arthur,et al. Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid. , 2006, Biochimica et biophysica acta.
[42] Shuibang Wang,et al. Nitric oxide activation of Erk1/2 regulates the stability and translation of mRNA transcripts containing CU-rich elements , 2006, Nucleic acids research.
[43] H. C. Carter,et al. Effect of moderate hypothermia on gene expression by THP-1 cells: a DNA microarray study. , 2006, Physiological genomics.
[44] A. Sorisky,et al. Macrophage-conditioned medium inhibits the differentiation of 3T3-L1 and human abdominal preadipocytes , 2006, Diabetologia.
[45] L. Karlsson,et al. Anti-Inflammatory Activity in Vitro and in Vivo of the Protein Farnesyltransferase Inhibitor Tipifarnib , 2006, Journal of Pharmacology and Experimental Therapeutics.
[46] Rongsong Li,et al. Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC , 2006, Circulation research.
[47] K. Barker,et al. Coculture of THP-1 human mononuclear cells with Candida albicans results in pronounced changes in host gene expression. , 2005, The Journal of infectious diseases.
[48] W. A. Bradley,et al. Inhibition of Lipopolysaccharide-Induced Inflammatory Responses by an Apolipoprotein AI Mimetic Peptide , 2005, Circulation research.
[49] Katherine E. M. Hoops,et al. Two Discrete Promoters Regulate the Alternatively Spliced Human Interferon Regulatory Factor-5 Isoforms , 2005, Journal of Biological Chemistry.
[50] A. Szántó,et al. Retinoids Potentiate Peroxisome Proliferator-Activated Receptor γ Action in Differentiation, Gene Expression, and Lipid Metabolic Processes in Developing Myeloid Cells , 2005, Molecular Pharmacology.
[51] Y. Pak,et al. HMG-CoA Reductase Inhibition Reduces Monocyte CC Chemokine Receptor 2 Expression and Monocyte Chemoattractant Protein-1–Mediated Monocyte Recruitment In Vivo , 2005, Circulation.
[52] M. Fraga,et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer , 2005, Nature Genetics.
[53] J. Kang,et al. The Amyloid-β Peptide Suppresses Transforming Growth Factor-β1-induced Matrix Metalloproteinase-2 Production via Smad7 Expression in Human Monocytic THP-1 Cells* , 2005, Journal of Biological Chemistry.
[54] S. Tonstad,et al. Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms Published, JLR Papers in Press, November 16, 2004. DOI 10.1194/jlr.M400324-JLR200 , 2005, Journal of Lipid Research.
[55] Christian Stehlik,et al. PAN1/NALP2/PYPAF2, an Inducible Inflammatory Mediator That Regulates NF-κB and Caspase-1 Activation in Macrophages* , 2004, Journal of Biological Chemistry.
[56] Silvano Sozzani,et al. The chemokine system in diverse forms of macrophage activation and polarization. , 2004, Trends in immunology.
[57] V. Ambros. The functions of animal microRNAs , 2004, Nature.
[58] L. Lanting,et al. Growth factors induce monocyte binding to vascular smooth muscle cells: implications for monocyte retention in atherosclerosis. , 2004, American journal of physiology. Cell physiology.
[59] A. Hamsten,et al. Effect of macrophage differentiation and exposure to mildly oxidized LDL on the proteolytic repertoire of THP-1 monocytes Published, JLR Papers in Press, June 21, 2004. DOI 10.1194/jlr.M400195-JLR200 , 2004, Journal of Lipid Research.
[60] Lin He,et al. MicroRNAs: small RNAs with a big role in gene regulation , 2004, Nature Reviews Genetics.
[61] Esteban Ballestar,et al. DNA Methylation Polymorphisms Precede Any Histological Sign of Atherosclerosis in Mice Lacking Apolipoprotein E* , 2004, Journal of Biological Chemistry.
[62] M. Jaye,et al. Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins. , 2004, Free radical biology & medicine.
[63] B. Finlay,et al. Differential post‐transcriptional activation of human phagocytes by different Pseudomonas aeruginosa isolates , 2004, Cellular microbiology.
[64] Peter A. Jones,et al. Epigenetics in human disease and prospects for epigenetic therapy , 2004, Nature.
[65] S. Peñuelas,et al. Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages. , 2004, Biochemical and biophysical research communications.
[66] G. Núñez,et al. Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. , 2004, The Journal of biological chemistry.
[67] L. McDaniel,et al. Use of cDNA microarrays to analyze responses to pneumococcal virulence factors. , 2004, The Indian journal of medical research.
[68] D. Bartel,et al. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs , 2004, Nature Reviews Genetics.
[69] H. Aburatani,et al. A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage. , 2004, Journal of atherosclerosis and thrombosis.
[70] Ashok Kumar,et al. Tumor Necrosis Factor-α Induces Functionally Active Hyaluronan-adhesive CD44 by Activating Sialidase through p38 Mitogen-activated Protein Kinase in Lipopolysaccharide-stimulated Human Monocytic Cells* , 2003, Journal of Biological Chemistry.
[71] R. Heinzen,et al. Comparative DNA Microarray Analysis of Host Cell Transcriptional Responses to Infection by Coxiella burnetii or Chlamydia trachomatis , 2003, Annals of the New York Academy of Sciences.
[72] M. Popp,et al. A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[73] G. Sacks,et al. Pneumolysin-Dependent and -Independent Gene Expression Identified by cDNA Microarray Analysis of THP-1 Human Mononuclear Cells Stimulated by Streptococcus pneumoniae , 2003, Infection and Immunity.
[74] F. Fernández‐Avilés,et al. Cooperation Between Secretory Phospholipase A2 and TNF-Receptor Superfamily Signaling: Implications for the Inflammatory Response in Atherogenesis , 2002, Circulation research.
[75] M. Gawaz,et al. A Critical Role of Platelet Adhesion in the Initiation of Atherosclerotic Lesion Formation , 2002, The Journal of experimental medicine.
[76] N. Maitland,et al. Macrophages in gene therapy: cellular delivery vehicles and in vivo targets , 2002, Journal of leukocyte biology.
[77] J. Cavaillon,et al. Gamma Interferon and Granulocyte/Monocyte Colony-stimulating Factor Prevent Endotoxin Tolerance in Human Monocytes by Promoting Interleukin-1 Receptor-associated Kinase Expression and Its Association to MyD88 and Not by Modulating TLR4 Expression* , 2002, The Journal of Biological Chemistry.
[78] H. Koyama,et al. Induction of Bone-Type Alkaline Phosphatase in Human Vascular Smooth Muscle Cells: Roles of Tumor Necrosis Factor-&agr; and Oncostatin M Derived From Macrophages , 2002, Circulation research.
[79] M. Willingham,et al. Triglyceride depletion in THP-1 cells alters cholesteryl ester physical state and cholesterol efflux. , 2002, Journal of lipid research.
[80] David Baltimore,et al. Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[81] F. Parhami,et al. Monocyte/Macrophage Regulation of Vascular Calcification In Vitro , 2002, Circulation.
[82] M. Turunen,et al. DNA hypomethylation and methyltransferase expression in atherosclerotic lesions , 2002, Vascular medicine.
[83] D. Shiffman,et al. Oxidized Low Density Lipoprotein Exposure Alters the Transcriptional Response of Macrophages to Inflammatory Stimulus* , 2001, The Journal of Biological Chemistry.
[84] S. Howell,et al. Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach , 2001, Immunology.
[85] S. Kihara,et al. Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages , 2001, Circulation.
[86] Roland Somogyi,et al. Large Scale Gene Expression Analysis of Cholesterol-loaded Macrophages* , 2000, The Journal of Biological Chemistry.
[87] Michael Q. Zhang,et al. Large-scale human promoter mapping using CpG islands , 2000, Nature Genetics.
[88] U. Ikeda,et al. Interaction between monocytes and vascular smooth muscle cells enhances matrix metalloproteinase-1 production. , 2000, Journal of cardiovascular pharmacology.
[89] S. Galiègue,et al. Monitoring Cellular Responses to Listeria monocytogenes with Oligonucleotide Arrays* , 2000, The Journal of Biological Chemistry.
[90] E. Edelman,et al. Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplasty. , 2000, The Journal of clinical investigation.
[91] G. Baumann,et al. Cellular adhesion molecules on vascular smooth muscle cells. , 1999, Cardiovascular research.
[92] D. Morel,et al. Cholesterol metabolism and efflux in human THP-1 macrophages. , 1998, Arteriosclerosis, thrombosis, and vascular biology.
[93] P. Libby,et al. Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability. , 1998, Circulation research.
[94] T. McCaffrey,et al. Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells. , 1997, The Journal of clinical investigation.
[95] E. Anggard,et al. Substantial inhibition of neo-intimal response to balloon injury in the rat carotid artery using a combination of antibodies to platelet-derived growth factor-BB and basic fibroblast growth factor. , 1997, Atherosclerosis.
[96] T. Springer,et al. Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18. , 1996, Blood.
[97] A. Tall,et al. Interleukin 8 Is Induced by Cholesterol Loading of Macrophages and Expressed by Macrophage Foam Cells in Human Atheroma (*) , 1996, The Journal of Biological Chemistry.
[98] E. Fitzke,et al. Differences in the state of differentiation of THP‐1 cells induced by phorbol ester and 1,25‐dihydroxyvitamin D3 , 1996, Journal of leukocyte biology.
[99] I. Goldberg. Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. , 1996, Journal of Lipid Research.
[100] S. Yeaman,et al. Impaired mobilisation of cholesterol from stored cholesteryl esters in human (THP-1) macrophages. , 1996, Atherosclerosis.
[101] J. Dayer,et al. Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones. , 1995, Immunology.
[102] T. Krakauer. A sensitive ELISA for measuring the adhesion of leukocytic cells to human endothelial cells. , 1994, Journal of immunological methods.
[103] W. Edwards,et al. Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis. , 1994, The Journal of clinical investigation.
[104] J. Suttles,et al. T cell-macrophage cognate interaction in the activation of macrophage effector function by Th2 cells. , 1993, Journal of immunology.
[105] R. Ross. The pathogenesis of atherosclerosis: a perspective for the 1990s , 1993, Nature.
[106] S. Wahl,et al. Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines. , 1991, Journal of immunology.
[107] S. Wahl,et al. Lipopolysaccharide, tumor necrosis factor-alpha, and IL-1 beta prevent programmed cell death (apoptosis) in human peripheral blood monocytes. , 1991, Journal of immunology.
[108] J. Auwerx,et al. The human leukemia cell line, THP-1: A multifacetted model for the study of monocyte-macrophage differentiation , 1991, Experientia.
[109] M. Menju,et al. Expression of the apolipoprotein E gene in a human macrophage-like cell line, THP-1. , 1989, Journal of biochemistry.
[110] T S Edgington,et al. A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11b/CD18 (Mac-1). , 1988, Journal of immunology.
[111] D. Altieri,et al. The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor. , 1988, The Journal of biological chemistry.
[112] M. Dell'aquila,et al. Characterization of a Colony‐Stimulating Factor Produced by the Human Monocytic Leukemia Cell Line, THP‐1 , 1986, Journal of leukocyte biology.
[113] M. Phillips,et al. Cellular cholesteryl ester clearance. Relationship to the physical state of cholesteryl ester inclusions. , 1983, The Journal of biological chemistry.
[114] K. Tada,et al. Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. , 1982, Cancer research.
[115] Shigeru Tsuchiya,et al. Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1) , 1980, International journal of cancer.
[116] G. Shipley,et al. Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques. , 1976, The Journal of clinical investigation.
[117] E. Scarano,et al. DNA Methylation , 1973, Nature.
[118] C. Peterson,et al. Adipose tissue macrophages in insulin resistant subjects are 1 associated with collagen VI, fibrosis and demonstrate 2 alternative activation , 2010 .
[119] J. Kang,et al. The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells. , 2005, The Journal of biological chemistry.
[120] R. Zager,et al. Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression. , 2003, The American journal of pathology.
[121] M. Wabitsch,et al. Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation , 2001, International Journal of Obesity.
[122] M. Hussain. A proposed model for the assembly of chylomicrons. , 2000, Atherosclerosis.
[123] P. Bongrand,et al. Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106). , 1998, Blood.
[124] C. Dyer,et al. THP-1 cells form foam cells in response to coculture with lipoproteins but not platelets. , 1991, Journal of lipid research.