Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis.
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T. Spector | F. Dudbridge | C. Mamotte | R. Prince | D. Hart | B. Mullin | Scott G Wilson | S. Wilson | S. Wilson | Scott G Wilson
[1] R. Prince,et al. Oestrogen effects on calcium membrane transport: A new view of the inter-relationship between oestrogen deficiency and age-related osteoporosis , 2010, Osteoporosis International.
[2] T. Spector,et al. Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. , 2008, American journal of human genetics.
[3] Christoph Lange,et al. Testing and Estimating Gene–Environment Interactions in Family‐Based Association Studies , 2008, Biometrics.
[4] Daniel L. Koller,et al. Meta‐Analysis of Genome‐Wide Scans Provides Evidence for Sex‐ and Site‐Specific Regulation of Bone Mass , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[5] T. Spector,et al. Variation in the FLNB gene regulates bone density in two populations of Caucasian women , 2007 .
[6] G. Hendy,et al. A functional polymorphism in the PTHR1 promoter region is associated with adult height and BMD measured at the femoral neck in a large cohort of young caucasian women , 2006, Human Genetics.
[7] Kim W. Carter,et al. JLIN: A java based linkage disequilibrium plotter , 2006, BMC Bioinformatics.
[8] Majd Zayzafoon,et al. RhoA and Cytoskeletal Disruption Mediate Reduced Osteoblastogenesis and Enhanced Adipogenesis of Human Mesenchymal Stem Cells in Modeled Microgravity , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[9] K. Michaëlsson,et al. Genetic liability to fractures in the elderly. , 2005, Archives of internal medicine.
[10] A. Uitterlinden,et al. Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study. , 2005, Human molecular genetics.
[11] Geoffrey B. Nilsen,et al. Whole-Genome Patterns of Common DNA Variation in Three Human Populations , 2005, Science.
[12] F. Islam,et al. Klotho Gene Polymorphisms are Associated with Osteocalcin Levels but not Bone Density of Aged Postmenopausal Women , 2005, Calcified Tissue International.
[13] Hui Shen,et al. A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27 , 2004, Journal of Medical Genetics.
[14] Christopher S. Chen,et al. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. , 2004, Developmental cell.
[15] E. N. Miller,et al. Evidence for a cluster of genes on chromosome 17q11–q21 controlling susceptibility to tuberculosis and leprosy in Brazilians , 2004, Genes and Immunity.
[16] John Blangero,et al. Quantitative Trait Loci on Chromosomes 2p, 4p, and 13q Influence Bone Mineral Density of the Forearm and Hip in Mexican Americans , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[17] F. Shanahan,et al. Suggestive Linkage of 2p22-25 and 11q12-13 with Low Bone Mineral Density at the Lumbar Spine in the Irish Population , 2003, Calcified Tissue International.
[18] T. Spector,et al. Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36. , 2003, American journal of human genetics.
[19] Krister Wennerberg,et al. XPLN, a Guanine Nucleotide Exchange Factor for RhoA and RhoB, But Not RhoC* , 2002, The Journal of Biological Chemistry.
[20] Hui Shen,et al. A whole-genome linkage scan suggests several genomic regions potentially containing quantitative trait Loci for osteoporosis. , 2002, The Journal of clinical endocrinology and metabolism.
[21] D. Kiel,et al. Genome Screen for Quantitative Trait Loci Contributing to Normal Variation in Bone Mineral Density: The Framingham Study , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[22] M. Devoto,et al. Variance component linkage analysis indicates a QTL for femoral neck bone mineral density on chromosome 1p36. , 2001, Human molecular genetics.
[23] N M Laird,et al. Family-based tests of association in the presence of linkage. , 2000, American journal of human genetics.
[24] Daniel L. Koller,et al. Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis. , 2000, The Journal of clinical endocrinology and metabolism.
[25] K. Hruska,et al. Rho-A Is Critical for Osteoclast Podosome Organization, Motility, and Bone Resorption* , 2000, The Journal of Biological Chemistry.
[26] T. Spector,et al. Family History of Appendicular Fracture and Risk of Osteoporosis: A Population-Based Study , 1999, Osteoporosis International.
[27] J. Ott,et al. First-stage autosomal genome screen in extended pedigrees suggests genes predisposing to low bone mineral density on chromosomes 1p, 2p and 4q , 1998, European Journal of Human Genetics.
[28] Lakkakorpi Pt,et al. Cytoskeletal changes in osteoclasts during the resorption cycle. , 1996 .
[29] P. Goss,et al. Do genetic factors explain associations between muscle strength, lean mass, and bone density? A twin study. , 1996, The American journal of physiology.
[30] H. Väänänen,et al. Cytoskeletal changes in osteoclasts during the resorption cycle , 1996, Microscopy research and technique.
[31] J. Wark,et al. Bone density determinants in elderly women: A twin study , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[32] S. Narumiya,et al. The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts. , 1995, Journal of cell science.
[33] J. Hopper,et al. Determinants of bone mass in 10‐ to 26‐year‐old females: A twin study , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[34] J. Kanis,et al. DIAGNOSIS OF OSTEOPOROSIS , 2016 .
[35] J. Norman,et al. Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins , 1994, The Journal of cell biology.
[36] B. Dawson-Hughes,et al. Heritable and life‐style determinants of bone mineral density , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[37] K. Väänänen,et al. Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro , 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[38] A. Hall,et al. Microinjection of recombinant p21rho induces rapid changes in cell morphology , 1990, The Journal of cell biology.
[39] M. Johns,et al. Purification of human genomic DNA from whole blood using sodium perchlorate in place of phenol. , 1989, Analytical biochemistry.
[40] R. Evans,et al. Bone mass is low in relatives of osteoporotic patients. , 1988, Annals of internal medicine.
[41] J. Kanehisa,et al. Osteoclastic bone resorption: in vitro analysis of the rate of resorption and migration of individual osteoclasts. , 1988, Bone.
[42] J. Hopper,et al. Genetic determinants of bone mass in adults. A twin study. , 1987, The Journal of clinical investigation.
[43] J. Christian,et al. Genetic factors in determining bone mass. , 1973, The Journal of clinical investigation.