Investigation of biological tissues using PM-fiber-based polarization sensitive optical coherence tomography

A PM fiber based PS OCT setup with simultaneous acquisition of signals in orthogonal polarization channels with an isolation ratio > 28 dB was created. The principles of measuring the tissue birefringence based on detecting only an envelope of OCT signal in the orthogonal polarization were described. The birefringence and depolarization degree of in vivo and ex vivo biotissues of different types were investigated.

[1]  M. V. van Gemert,et al.  Two-dimensional birefringence imaging in biological tissue using polarization-sensitive optical coherence tomography , 1997, European Conference on Biomedical Optics.

[2]  J M Schmitt,et al.  Cross-polarized backscatter in optical coherence tomography of biological tissue. , 1998, Optics letters.

[3]  M J Everett,et al.  Mapping of Birefringence and Thermal Damage in Tissue by use of Polarization-Sensitive Optical Coherence Tomography. , 1998, Applied optics.

[4]  G. Ripandelli,et al.  Optical coherence tomography. , 1998, Seminars in ophthalmology.

[5]  J. Nelson,et al.  High-speed fiber based polarization-sensitive optical coherence tomography of in vivo human skin. , 2000, Optics letters.

[6]  J. Izatt,et al.  Simplified method for polarization-sensitive optical coherence tomography. , 2001, Optics letters.

[7]  A. Fercher,et al.  Measurement and imaging of birefringence and optic axis orientation by phase resolved polarization sensitive optical coherence tomography. , 2001, Optics express.

[8]  Mark C. Pierce,et al.  In vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer by polarization-sensitive optical coherence tomography , 2002 .

[9]  Daniel Fried,et al.  Imaging caries lesions and lesion progression with polarization-sensitive optical coherence tomography , 2002, SPIE BiOS.

[10]  Vladislav A. Kamensky,et al.  Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value , 2002 .

[11]  Valentin M. Gelikonov,et al.  Time correlation analysis of the propagation of low-coherence radiation in an optical channel with imperfections of anisotropy , 2002 .

[12]  Roman Kuranov,et al.  Complementary use of cross-polarization and standard OCT for differential diagnosis of pathological tissues. , 2002, Optics express.

[13]  Mark C. Pierce,et al.  Real-time multifunctional optical coherence tomography , 2003, SPIE BiOS.

[14]  Roman V. Kuranov.  INTERFEROMETRY: Time-correlation analysis of low-coherence interference schemes with an arbitrary number of anisotropy defects in an optical path , 2003 .

[15]  T. Milner,et al.  Polarization-maintaining fiber-based optical low-coherence reflectometer for characterization and ranging of birefringence. , 2003, Optics letters.