HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice
暂无分享,去创建一个
C. Grimm | M. Samardzija | G. Zeck | A. Corna | E. Zrenner | P. Boya | M. Ueffing | P. de la Villa | J. Roger | D. Trifunović | M. Jarboui | Raquel Gomez-Sintes | A. Armento | Eleni Petridou | Wadood Haq | F. Paquet-Durand
[1] N. Mizushima,et al. Diverse Cellular Roles of Autophagy. , 2019, Annual review of cell and developmental biology.
[2] C. Grimm,et al. Light stress affects cones and horizontal cells via rhodopsin-mediated mechanisms. , 2019, Experimental eye research.
[3] T. Langmann,et al. Microglia in Retinal Degeneration , 2019, Front. Immunol..
[4] Hyungwon Choi,et al. Moving beyond P values: data analysis with estimation graphics , 2019, Nature Methods.
[5] Diana Romero. HDAC inhibitors tested in phase III trial , 2019, Nature Reviews Clinical Oncology.
[6] C. Cepko,et al. Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa , 2019, Proceedings of the National Academy of Sciences.
[7] R. Shah. Safety and Tolerability of Histone Deacetylase (HDAC) Inhibitors in Oncology , 2019, Drug Safety.
[8] Franck P. Martial,et al. Measuring vision using innate behaviours in mice with intact and impaired retina function , 2019, Scientific Reports.
[9] G. Kroemer,et al. Biological Functions of Autophagy Genes: A Disease Perspective , 2019, Cell.
[10] Runan Yao,et al. iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data , 2018, BMC Bioinformatics.
[11] U. Greferath,et al. Failure of Autophagy-Lysosomal Pathways in Rod Photoreceptors Causes the Early Retinal Degeneration Phenotype Observed in Cln6nclf Mice. , 2018, Investigative ophthalmology & visual science.
[12] D. Klionsky,et al. Inhibiting autophagy reduces retinal degeneration caused by protein misfolding , 2018, Autophagy.
[13] J. Bergh,et al. EMA Review of Panobinostat (Farydak) for the Treatment of Adult Patients with Relapsed and/or Refractory Multiple Myeloma , 2018, The oncologist.
[14] Denis Torre,et al. BioJupies: Automated Generation of Interactive Notebooks for RNA-seq Data Analysis in the Cloud , 2018, bioRxiv.
[15] Sonia Tarazona,et al. PaintOmics 3: a web resource for the pathway analysis and visualization of multi-omics data , 2018, bioRxiv.
[16] Thomas Euler,et al. Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration , 2018, Proceedings of the National Academy of Sciences.
[17] M. Biel,et al. Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa , 2018, Front. Immunol..
[18] P. Campochiaro,et al. The mechanism of cone cell death in Retinitis Pigmentosa , 2017, Progress in Retinal and Eye Research.
[19] F. Rieke,et al. Stimulation of functional neuronal regeneration from Müller glia in adult mice , 2017, Nature.
[20] D. Agoston. How to Translate Time? The Temporal Aspect of Human and Rodent Biology , 2017, Front. Neurol..
[21] A. Urtti,et al. Pharmacokinetic aspects of retinal drug delivery , 2017, Progress in Retinal and Eye Research.
[22] R. Casson,et al. A review of the mechanisms of cone degeneration in retinitis pigmentosa , 2016, Acta ophthalmologica.
[23] S. Tsang,et al. Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration. , 2016, The Journal of clinical investigation.
[24] P. Boya,et al. Autophagy in the eye: Development, degeneration, and aging , 2016, Progress in Retinal and Eye Research.
[25] B. Arango-Gonzalez,et al. HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo. , 2016, Human molecular genetics.
[26] Thomas Euler,et al. Calcium dynamics change in degenerating cone photoreceptors. , 2016, Human molecular genetics.
[27] Marc Hafner,et al. L1000CDS2: LINCS L1000 characteristic direction signatures search engine , 2016, npj Systems Biology and Applications.
[28] Marco Y. Hein,et al. The Perseus computational platform for comprehensive analysis of (prote)omics data , 2016, Nature Methods.
[29] R. Aebersold,et al. On the Dependency of Cellular Protein Levels on mRNA Abundance , 2016, Cell.
[30] O. L. Moritz,et al. NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration. , 2016, Human molecular genetics.
[31] H. Kaplan,et al. Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa. , 2016, Cell reports.
[32] K. Kaarniranta,et al. Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes. , 2016, European journal of pharmacology.
[33] C. Punzo,et al. Improved cell metabolism prolongs photoreceptor survival upon retinal-pigmented epithelium loss in the sodium iodate induced model of geographic atrophy , 2016, Oncotarget.
[34] Peer Bork,et al. Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats , 2015, Cell systems.
[35] J. Laubach,et al. Panobinostat for the Treatment of Multiple Myeloma , 2015, Clinical Cancer Research.
[36] F. Schottler,et al. Autophagy supports color vision , 2015, Autophagy.
[37] W. Gan,et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration , 2015, EMBO molecular medicine.
[38] S. E. Barker,et al. Long-term effect of gene therapy on Leber's congenital amaurosis. , 2015, The New England journal of medicine.
[39] T. Léveillard,et al. Rod-Derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis , 2015, Cell.
[40] C. Punzo,et al. Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. , 2015, The Journal of clinical investigation.
[41] R. Apte,et al. Autophagy supports survival and phototransduction protein levels in rod photoreceptors , 2015, Cell Death and Differentiation.
[42] T. Léveillard,et al. Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration. , 2015, The Journal of clinical investigation.
[43] P. Boya,et al. Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa , 2014, Cell Death and Differentiation.
[44] Thomas Euler,et al. Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration , 2014, PloS one.
[45] S. Mitter,et al. Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD , 2014, Autophagy.
[46] KumarAtul,et al. Efficacy of oral valproic acid in patients with retinitis pigmentosa. , 2014 .
[47] Jacqueline S. Stevens,et al. Histone deacetylase inhibition induces long-lasting changes in maternal behavior and gene expression in female mice. , 2014, Endocrinology.
[48] A. Bird,et al. Geographic atrophy: a histopathological assessment. , 2014, JAMA ophthalmology.
[49] Günther Zeck,et al. Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury , 2014, Front. Cell. Neurosci..
[50] A. Dinculescu,et al. Review: The history and role of naturally occurring mouse models with Pde6b mutations , 2013, Molecular vision.
[51] C. Grimm,et al. p38 MAPK signaling acts upstream of LIF-dependent neuroprotection during photoreceptor degeneration , 2013, Cell Death and Disease.
[52] K. Fujita,et al. Assessing quality of life in the treatment of patients with age-related macular degeneration: clinical research findings and recommendations for clinical practice , 2013, Clinical ophthalmology.
[53] C. Cepko,et al. Retinal gene therapy coming of age. , 2013, Human gene therapy.
[54] Andreas Hierlemann,et al. Recording from defined populations of retinal ganglion cells using a high-density CMOS-integrated microelectrode array with real-time switchable electrode selection , 2012, Journal of Neuroscience Methods.
[55] S. Akbarian,et al. Epigenetic mechanisms in neurological disease , 2012, Nature Medicine.
[56] Thomas Euler,et al. Light-Driven Calcium Signals in Mouse Cone Photoreceptors , 2012, The Journal of Neuroscience.
[57] P. Matthias,et al. Interplay between histone deacetylases and autophagy ‐ from cancer therapy to neurodegeneration , 2012, Immunology and cell biology.
[58] R. Masland,et al. Physiological clustering of visual channels in the mouse retina. , 2011, Journal of neurophysiology.
[59] K. Yau,et al. Intrinsically photosensitive retinal ganglion cells. , 2010, Physiological reviews.
[60] Karl Deisseroth,et al. Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa , 2010, Science.
[61] S. Jacobson,et al. The genomic, biochemical, and cellular responses of the retina in inherited photoreceptor degenerations and prospects for the treatment of these disorders. , 2010, Annual review of neuroscience.
[62] B. Vanhaesebroeck,et al. The emerging mechanisms of isoform-specific PI3K signalling , 2010, Nature Reviews Molecular Cell Biology.
[63] V. Sée,et al. p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma , 2010, Cell Death and Disease.
[64] Sheng-Kwei Song,et al. Vitreous Volume of the Mouse Measured by Quantitative High-Resolution MRI , 2010 .
[65] P. Farinelli,et al. Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse , 2010, Cell Death and Disease.
[66] Constance L. Cepko,et al. HDAC4 Regulates Neuronal Survival in Normal and Diseased Retinas , 2009, Science.
[67] E. Clementi,et al. HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment , 2008, Proceedings of the National Academy of Sciences.
[68] E. Seto,et al. HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention , 2007, Oncogene.
[69] S. Daiger,et al. Perspective on genes and mutations causing retinitis pigmentosa. , 2007, Archives of ophthalmology.
[70] T. Miyakawa,et al. Light/dark Transition Test for Mice , 2006, Journal of visualized experiments : JoVE.
[71] S. Perlman,et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia , 2006, Nature chemical biology.
[72] C. Gentili,et al. Docosahexaenoic acid prevents apoptosis of retina photoreceptors by activating the ERK/MAPK pathway , 2006, Journal of neurochemistry.
[73] Jessica E. Bolden,et al. Anticancer activities of histone deacetylase inhibitors , 2006, Nature Reviews Drug Discovery.
[74] P. Campochiaro,et al. Antioxidants reduce cone cell death in a model of retinitis pigmentosa. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[75] M. O'Reilly,et al. RNAi‐based suppression and replacement of rds‐peripherin in retinal organotypic culture , 2006, Human mutation.
[76] C. Grimm,et al. Rpe65 as a modifier gene for inherited retinal degeneration , 2006, The European journal of neuroscience.
[77] J. Saklatvala. The p38 MAP kinase pathway as a therapeutic target in inflammatory disease. , 2004, Current opinion in pharmacology.
[78] T. Léveillard,et al. Identification and characterization of rod-derived cone viability factor , 2004, Nature Genetics.
[79] Vera Rogiers,et al. Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view. , 2004, Current medicinal chemistry.
[80] N. Bressler. Age-related macular degeneration is the leading cause of blindness... , 2004, JAMA.
[81] R. V. Rajala,et al. Involvement of Insulin/Phosphoinositide 3-Kinase/Akt Signal Pathway in 17β-Estradiol-mediated Neuroprotection* , 2004, Journal of Biological Chemistry.
[82] Sheila Nirenberg,et al. Classification of retinal ganglion cells: a statistical approach. , 2003, Journal of neurophysiology.
[83] M. Hascöet,et al. The mouse light/dark box test. , 2003, European journal of pharmacology.
[84] V. Rogiers,et al. Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. , 2002, Drug metabolism and disposition: the biological fate of chemicals.
[85] N. Holbrook,et al. Cellular response to oxidative stress: Signaling for suicide and survival * , 2002, Journal of cellular physiology.
[86] P. Marks,et al. Histone deacetylases and cancer: causes and therapies , 2001, Nature Reviews Cancer.
[87] T. Gardner,et al. Insulin Rescues Retinal Neurons from Apoptosis by a Phosphatidylinositol 3-Kinase/Akt-mediated Mechanism That Reduces the Activation of Caspase-3* , 2001, The Journal of Biological Chemistry.
[88] M. Karin,et al. Mammalian MAP kinase signalling cascades , 2001, Nature.
[89] D. F. Andrews,et al. A one-hit model of cell death in inherited neuronal degenerations , 2000, Nature.
[90] P. Marks,et al. Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors , 1999, Nature.
[91] F. Cross,et al. Accurate quantitation of protein expression and site-specific phosphorylation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[92] D. Dorsa,et al. The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons , 1999, The Journal of Neuroscience.
[93] R. Masland,et al. The Major Cell Populations of the Mouse Retina , 1998, The Journal of Neuroscience.
[94] F. Hobbs,et al. Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase* , 1998, The Journal of Biological Chemistry.
[95] M. Lavail,et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. , 1998, Investigative ophthalmology & visual science.
[96] S. Schreiber,et al. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs. , 1997, Current opinion in chemical biology.
[97] C. Curcio,et al. Photoreceptor loss in age-related macular degeneration. , 1996, Investigative ophthalmology & visual science.
[98] Michael E. Greenberg,et al. Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis , 1995, Science.
[99] K Y Hui,et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). , 1994, The Journal of biological chemistry.
[100] M. Lavail,et al. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[101] Bert Sakmann,et al. Scotopic and mesopic light adaptation in the cat's retina , 1969, Pflügers Archiv.
[102] M. Samardzija,et al. HDAC Inhibition Prevents Primary Cone Degeneration Even After the Onset of Degeneration. , 2019, Advances in experimental medicine and biology.
[103] M. Ueffing,et al. Primary Rod and Cone Degeneration Is Prevented by HDAC Inhibition. , 2018, Advances in experimental medicine and biology.
[104] S. Tsang,et al. Success of Gene Therapy in Late-Stage Treatment. , 2018, Advances in experimental medicine and biology.
[105] G. Perea,et al. A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer’s Disease Mice , 2017, Neuropsychopharmacology.
[106] Atul Kumar,et al. Efficacy of oral valproic acid in patients with retinitis pigmentosa. , 2014, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
[107] Soichi Watanabe,et al. ICNIRP Guidelines on Limits of Exposure to Laser Radiation of Wavelengths between 180 nm and 1,000 μm. , 2013, Health physics.
[108] T. Katome,et al. Diagnostic imaging in patients with retinitis pigmentosa. , 2012, The journal of medical investigation : JMI.
[109] C. Cepko,et al. Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa , 2009, Nature Neuroscience.
[110] E. Olson,et al. The many roles of histone deacetylases in development and physiology: implications for disease and therapy , 2009, Nature Reviews Genetics.
[111] Z. Marinova,et al. The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons , 2009, Molecular Psychiatry.
[112] A. Meijer,et al. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. , 1997, European journal of biochemistry.
[113] S. Liebowitz. Retinitis pigmentosa. , 1979, Journal - American Intra-Ocular Implant Society.
[114] Joaquín Dopazo,et al. Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data , 2010, Bioinform..