Classification of retinal fundus image using MS-DRLBP features and CNN-RBF classifier

The most common retinal diseases that are to be diagnosed are Diabetic Retinopathy (DR), Age-related Macular Degeneration (AMD) and Choroidal Neovascularization (CNV). For the people above 60 years of age, detection of these retinal diseases is an important task for treatment that reduces the risk of vision loss. Retinal fundus images play a significant role in the detection of DR, AMD and CNV disease diagnosis and treatment. The existing techniques for the detection of DR, AMD and CNV have not fulfilled with the classification accuracy of the retinal diseases effectively. This research work proposes an efficient classification framework for retinal fundus image recognition to overcome these drawbacks. Initially, the input image from the publicly available STARE database is preprocessed with the following three steps (a) Specular reflection removal and smoothing, (b) contrast enhancement and (c) retinal region expansion. With the preprocessed image, the features are extracted using Multi-Scale Discriminative Robust Local Binary Pattern (MS-DRLBP), based on RGB component selection, Gradient operation, and LBP descriptor. Finally, classification was done using hybrid Convolution Neural Network (CNN) and Radial Basis Function (RBF) model (CNN-RBF) which classifies the retinal fundus images into four classes such as DR, AMD, CNV and Normal (NR). Experimental results of the proposed method gives an accuracy of 97.22% compared with the existing other methodologies.

[1]  Qinyan Zhang,et al.  Classification of Cataract Fundus Image Based on Retinal Vascular Information , 2016, ICSH.

[2]  Frédéric Zana,et al.  Segmentation of vessel-like patterns using mathematical morphology and curvature evaluation , 2001, IEEE Trans. Image Process..

[3]  Kevin Noronha,et al.  Automated detection of age-related macular degeneration using empirical mode decomposition , 2015, Knowl. Based Syst..

[4]  Esa Prakasa,et al.  Texture Feature Extraction by Using Local Binary Pattern , 2016 .

[5]  Qinyan Zhang,et al.  Application of SVM based on genetic algorithm in classification of cataract fundus images , 2017, 2017 IEEE International Conference on Imaging Systems and Techniques (IST).

[6]  N. Prakash,et al.  An Efficient Detection System for Screening Glaucoma in Retinal Images , 2017 .

[7]  Asha Gowda Karegowda,et al.  A Comparative Study on Filters with Special Reference to Retinal Images , 2016 .

[8]  Omer Deperlioglu,et al.  An enhanced diabetic retinopathy detection and classification approach using deep convolutional neural network , 2019, Neural Computing and Applications.

[9]  Haizhou Ai,et al.  Demographic Classification with Local Binary Patterns , 2007, ICB.

[10]  Augustinus Laude,et al.  An Integrated Diabetic Retinopathy Index for the Diagnosis of Retinopathy Using Digital Fundus Image Features , 2013 .

[11]  M. Arthanari,et al.  DETECTION OF DIABETIC RETINOPATHY USING RADIAL BASIS FUNCTION , 2011 .

[12]  Marko Heikkilä,et al.  Description of interest regions with local binary patterns , 2009, Pattern Recognit..

[13]  Nashwa El-Bendary,et al.  Retinal Blood Vessel Segmentation Approach Based on Mathematical Morphology , 2015 .

[14]  Lucas J. van Vliet,et al.  An Automated System for the Detection and Classification of Retinal Changes Due to Red Lesions in Longitudinal Fundus Images , 2018, IEEE Transactions on Biomedical Engineering.

[15]  Anselmo Cardoso de Paiva,et al.  Texture based on geostatistic for glaucoma diagnosis from fundus eye image , 2017, Multimedia Tools and Applications.

[16]  Roberto Hornero,et al.  Neural network based detection of hard exudates in retinal images , 2009, Comput. Methods Programs Biomed..

[17]  Auli Damayanti Fuzzy learning vector quantization, neural network and fuzzy systems for classification fundus eye images with wavelet transformation , 2017, 2017 2nd International conferences on Information Technology, Information Systems and Electrical Engineering (ICITISEE).

[18]  Suman Shrestha Image Denoising using New Adaptive Based Median Filters , 2014, ArXiv.

[19]  U. Rajendra Acharya,et al.  Automated segmentation of exudates, haemorrhages, microaneurysms using single convolutional neural network , 2017, Inf. Sci..

[20]  Vaibhav V. Kamble,et al.  Automated diabetic retinopathy detection using radial basis function , 2020, Procedia Computer Science.

[21]  Loris Nanni,et al.  Local binary patterns variants as texture descriptors for medical image analysis , 2010, Artif. Intell. Medicine.

[22]  R GEETHARAMANI,et al.  Automatic segmentation of blood vessels from retinal fundus images through image processing and data mining techniques , 2015 .

[23]  Farida Cheriet,et al.  Automatic multiresolution age-related macular degeneration detection from fundus images , 2014, Medical Imaging.

[24]  Mohamed Elhoseny,et al.  An approach for de-noising and contrast enhancement of retinal fundus image using CLAHE , 2019, Optics & Laser Technology.

[25]  Matti Pietikäinen,et al.  Face Description with Local Binary Patterns: Application to Face Recognition , 2006, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[26]  Xudong Jiang,et al.  LBP-Based Edge-Texture Features for Object Recognition , 2014, IEEE Transactions on Image Processing.

[27]  Junhao Wen,et al.  Exudate Detection for Diabetic Retinopathy Using Pretrained Convolutional Neural Networks , 2020, Complex..

[28]  Patrick P. K. Chan,et al.  Vessel enhancement of low quality fundus image using mathematical morphology and combination of Gabor and matched filter , 2016, 2016 International Conference on Wavelet Analysis and Pattern Recognition (ICWAPR).

[29]  U. Raghavendra,et al.  Age-related Macular Degeneration detection using deep convolutional neural network , 2018, Future Gener. Comput. Syst..

[30]  Xiaochun Yang,et al.  A statistical approach to interactive image segmentation , 2011, 2011 International Conference on Multimedia Technology.

[31]  Moustapha Kardouchi,et al.  Diabetic Retinopathy Detection Using Machine Learning and Texture Features , 2018, 2018 IEEE Canadian Conference on Electrical & Computer Engineering (CCECE).

[32]  Bhabatosh Chanda,et al.  Multiscale morphological segmentation of gray-scale images , 2003, IEEE Trans. Image Process..

[33]  Matti Pietikäinen,et al.  A Generalized Local Binary Pattern Operator for Multiresolution Gray Scale and Rotation Invariant Texture Classification , 2001, ICAPR.

[34]  J. Anitha,et al.  Automated radial basis function neural network based image classification system for diabetic retinopathy detection in retinal images , 2010, International Conference on Digital Image Processing.

[35]  Kjersti Engan,et al.  Retinal Disease Screening Through Local Binary Patterns , 2017, IEEE Journal of Biomedical and Health Informatics.

[36]  Gui-Song Xia,et al.  Dynamic texture recognition by aggregating spatial and temporal features via ensemble SVMs , 2016, Neurocomputing.

[37]  U. Rajendra Acharya,et al.  Evolutionary algorithm based classifier parameter tuning for automatic diabetic retinopathy grading: A hybrid feature extraction approach , 2013, Knowl. Based Syst..

[38]  Sohini Roychowdhury Classification of large-scale fundus image data sets: A cloud-computing framework , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[39]  Changqing Shen,et al.  A hybrid technique based on convolutional neural network and support vector regression for intelligent diagnosis of rotating machinery , 2017 .

[40]  Qing Wang,et al.  Vessel Recognition of Retinal Fundus Images Based on Fully Convolutional Network , 2018, 2018 IEEE 42nd Annual Computer Software and Applications Conference (COMPSAC).

[41]  Damodar Reddy Edla,et al.  Diabetes Classification using Radial Basis Function Network by Combining Cluster Validity Index and BAT Optimization with Novel Fitness Function , 2017, Int. J. Comput. Intell. Syst..

[42]  T. Eftestøl,et al.  Using local binary pattern to classify dementia in MRI , 2012, 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI).

[43]  José Manuel Bravo,et al.  A New Supervised Method for Blood Vessel Segmentation in Retinal Images by Using Gray-Level and Moment Invariants-Based Features , 2011, IEEE Transactions on Medical Imaging.

[45]  R. Klein,et al.  The Wisconsin age-related maculopathy grading system. , 1991, Ophthalmology.

[46]  C. Chandrasekar,et al.  A Comparison of various Edge Detection Techniques used in Image Processing , 2012 .

[47]  V. Cipriani,et al.  Age-related macular degeneration and the complement system. , 2012, Immunobiology.

[48]  Nilamani Bhoi,et al.  An Unsupervised Approach for Extraction of Blood Vessels from Fundus Images , 2018, Journal of Digital Imaging.

[49]  Aggelos K. Katsaggelos,et al.  Local Binary Patterns used on Cardiac MRI to classify high and low risk patient groups , 2012, 2012 Proceedings of the 20th European Signal Processing Conference (EUSIPCO).

[50]  Matti Pietikäinen,et al.  Multiresolution Gray-Scale and Rotation Invariant Texture Classification with Local Binary Patterns , 2002, IEEE Trans. Pattern Anal. Mach. Intell..

[51]  Cemal Köse,et al.  Blood Vessel Extraction in Color Retinal Fundus Images with Enhancement Filtering and Unsupervised Classification , 2017, Journal of healthcare engineering.

[52]  S. Yusuf,et al.  The burden of disease in older people and implications for health policy and practice , 2015, The Lancet.

[53]  R. Hornero,et al.  Utility of a Radial Basis Function Classifier in the Detection of Red Lesions in Retinal Images , 2009 .

[54]  Arwa Ahmed Gasm Elseid,et al.  Evaluation of Spatial Filtering Techniques in Retinal Fundus Images , 2018 .

[55]  Boguslaw Obara,et al.  The Multiscale Bowler-Hat Transform for Blood Vessel Enhancement in Retinal Images , 2017, Pattern Recognit..

[56]  Sang Jun Park,et al.  Laterality Classification of Fundus Images Using Interpretable Deep Neural Network , 2018, Journal of Digital Imaging.

[57]  S. R. Dhanushkodi,et al.  Diagnosis System for Diabetic Retinopathy to Prevent Vision Loss , 2013 .

[58]  Javier Garrido,et al.  An exudate detection method for diagnosis risk of diabetic macular edema in retinal images using feature-based and supervised classification , 2018, Medical & Biological Engineering & Computing.

[59]  Yang Yan,et al.  Classification of Artery and Vein in Retinal Fundus Images Based on the Context-Dependent Features , 2017, HCI.

[60]  Hamid Reza Pourreza,et al.  Retinal vessel segmentation using color image morphology and local binary patterns , 2010, 2010 6th Iranian Conference on Machine Vision and Image Processing.