An Engineered Cysteine-Modified Diabody for Imaging Activated Leukocyte Cell Adhesion Molecule (ALCAM)-Positive Tumors
暂无分享,去创建一个
[1] H. Tseng,et al. Microfluidic-Based 18F-Labeling of Biomolecules for Immuno–Positron Emission Tomography , 2011, Molecular imaging.
[2] J. Reichert,et al. Development trends for human monoclonal antibody therapeutics , 2010, Nature Reviews Drug Discovery.
[3] G. Mælandsmo,et al. A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth , 2010, Cancer Immunology, Immunotherapy.
[4] A. Scott,et al. Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer. , 2010, Cancer biotherapy & radiopharmaceuticals.
[5] V. Rybin,et al. 68Ga-labelled recombinant antibody variants for immuno-PET imaging of solid tumours , 2010, European Journal of Nuclear Medicine and Molecular Imaging.
[6] Michael M. Schmidt,et al. A modeling analysis of the effects of molecular size and binding affinity on tumor targeting , 2009, Molecular Cancer Therapeutics.
[7] Carolyn J Anderson,et al. Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research. , 2009, Cancer biotherapy & radiopharmaceuticals.
[8] C. Anderson,et al. Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET). , 2009, Accounts of chemical research.
[9] Sven H. Hausner,et al. Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model. , 2009, Cancer research.
[10] M. Koch,et al. Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse , 2009, British Journal of Cancer.
[11] E. Diamandis,et al. Activated leukocyte cell adhesion molecule: A novel biomarker for breast cancer , 2009, International journal of cancer.
[12] N. van Bruggen,et al. Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma , 2009, The Journal of pathology.
[13] Joachim Feldwisch,et al. Targeting of HER2-Expressing Tumors with a Site-Specifically 99mTc-Labeled Recombinant Affibody Molecule, ZHER2:2395, with C-Terminally Engineered Cysteine , 2009, Journal of Nuclear Medicine.
[14] R. Ralhan,et al. Cytoplasmic accumulation of activated leukocyte cell adhesion molecule is a predictor of disease progression and reduced survival in oral cancer patients , 2009, International journal of cancer.
[15] Tara Heitner,et al. In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86Y- and 111In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor–Bearing Nude Mice , 2009, Journal of Nuclear Medicine.
[16] Anna M. Wu,et al. Antibodies and Antimatter: The Resurgence of Immuno-PET , 2008, Journal of Nuclear Medicine.
[17] A. Wu,et al. Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2. , 2008, Bioconjugate chemistry.
[18] A. Wu,et al. Engineered humanized diabodies for microPET imaging of prostate stem cell antigen-expressing tumors. , 2008, Protein engineering, design & selection : PEDS.
[19] J. Schalkwijk,et al. Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule. , 2008, Cancer research.
[20] Anna M Wu,et al. Antibodies for Molecular Imaging of Cancer , 2008, Cancer journal.
[21] Mattia Barbareschi,et al. Subcellular Localization of Activated Leukocyte Cell Adhesion Molecule Is a Molecular Predictor of Survival in Ovarian Carcinoma Patients , 2008, Clinical Cancer Research.
[22] Sanjiv S. Gambhir,et al. Dual-Function Probe for PET and Near-Infrared Fluorescence Imaging of Tumor Vasculature , 2007, Journal of Nuclear Medicine.
[23] C. Benz,et al. Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells , 2007, Molecular Cancer Therapeutics.
[24] J. Marks,et al. Recombinant full-length human IgG1s targeting hormone-refractory prostate cancer , 2007, Journal of Molecular Medicine.
[25] S. Morrison,et al. Targeting, Imaging, and Therapy Using a Humanized Antiprostate Stem Cell Antigen (PSCA) Antibody , 2007, Journal of immunotherapy.
[26] Martin G Pomper,et al. Radiolabeled Anti-Claudin 4 and Anti-Prostate Stem Cell Antigen: Initial Imaging in Experimental Models of Pancreatic Cancer , 2007, Molecular imaging.
[27] S. Gambhir,et al. PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody. , 2007, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[28] W. Weichert,et al. Cytoplasmic overexpression of ALCAM is prognostic of disease progression in breast cancer , 2006, Journal of Clinical Pathology.
[29] Ruedi Aebersold,et al. Pancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape. , 2005, Gastroenterology.
[30] Anna M Wu,et al. Arming antibodies: prospects and challenges for immunoconjugates , 2005, Nature Biotechnology.
[31] S. Gambhir,et al. Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging. , 2005, Cancer research.
[32] Andrea Bolognesi,et al. Internalization and recycling of ALCAM/CD166 detected by a fully human single-chain recombinant antibody , 2005, Journal of Cell Science.
[33] Christian Pilarsky,et al. Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival , 2005, The Journal of pathology.
[34] M Dietel,et al. ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival , 2004, Journal of Clinical Pathology.
[35] Troy Stevens,et al. Open Access Activated Leukocyte Cell Adhesion Molecule in Breast Cancer: Prognostic Indicator , 2022 .
[36] M. Herlyn,et al. Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis. , 2004, The Journal of investigative dermatology.
[37] Matthew R Cooperberg,et al. Mapping Tumor Epitope Space by Direct Selection of Single-Chain Fv Antibody Libraries on Prostate Cancer Cells , 2004, Cancer Research.
[38] Sanjiv Sam Gambhir,et al. AMIDE: a free software tool for multimodality medical image analysis. , 2003, Molecular imaging.
[39] J. Wong,et al. Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and t84.66 minibody: comparison to radioiodinated fragments. , 2001, Bioconjugate chemistry.
[40] Y. Arano. Strategies to reduce renal radioactivity levels of antibody fragments. , 1998, The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology.
[41] U. Boggi,et al. Initial tumor targeting, biodistribution, and pharmacokinetic evaluation of the monoclonal antibody PAM4 in patients with pancreatic cancer. , 1995, Cancer research.
[42] B. Haynes,et al. Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand , 1995, The Journal of experimental medicine.
[43] B. Haynes,et al. Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells , 1995, The Journal of experimental medicine.
[44] D. King,et al. High-Level Expression of a Recombinant Antibody from Myeloma Cells Using a Glutamine Synthetase Gene as an Amplifiable Selectable Marker , 1992, Bio/Technology.
[45] H. Tseng,et al. Microfluidic-Based 18 F-Labeling of Biomolecules for Immuno – Positron Emission Tomography , 2011 .
[46] S. Gambhir,et al. Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications. , 2004, Protein engineering, design & selection : PEDS.
[47] S. Loening,et al. ALCAM/CD166 is up‐regulated in low‐grade prostate cancer and progressively lost in high‐grade lesions , 2003, The Prostate.
[48] C. Milstein,et al. Preparation of monoclonal antibodies: strategies and procedures. , 1981, Methods in enzymology.
[49] C. Milstein,et al. [1] Preparation of monoclonal antibodies: Strategies and procedures , 1981 .