TECPR1 provides E3-ligase like activity to the ATG5-ATG12 complex to conjugate LC3/ATG8 to damaged lysosomes
暂无分享,去创建一个
P. Verkade | Yingxue Wang | M. Jefferson | U. Mayer | T. Wileman | M. Whelband | J. Mccoll | Kristine Kreuzer
[1] C. Münch,et al. A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins , 2023, Nature Cell Biology.
[2] J. Stewart,et al. Control of infection by LC3-associated phagocytosis, CASM, and detection of raised vacuolar pH by the V-ATPase-ATG16L1 axis , 2022, Science advances.
[3] T. Finkel,et al. A phosphoinositide signalling pathway mediates rapid lysosomal repair , 2022, Nature.
[4] A. Ballabio,et al. GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis , 2021, Science advances.
[5] O. Florey,et al. V-ATPase is a universal regulator of LC3 associated phagocytosis and non-canonical autophagy , 2021, bioRxiv.
[6] A. Ballabio,et al. LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury , 2020, Nature Cell Biology.
[7] S. Blanchard,et al. TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes , 2020, Nature Communications.
[8] Michael I. Wilson,et al. Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine , 2020, bioRxiv.
[9] K. Öllinger,et al. Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins , 2020, Cell Death & Disease.
[10] Lin Li,et al. A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy , 2019, Cell.
[11] G. Kroemer,et al. Biological Functions of Autophagy Genes: A Disease Perspective , 2019, Cell.
[12] H. Stenmark,et al. ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival , 2018, The EMBO journal.
[13] P. Hanson,et al. Triggered recruitment of ESCRT machinery promotes endolysosomal repair , 2018, Science.
[14] B. Phinney,et al. Galectins Control mTOR in Response to Endomembrane Damage. , 2018, Molecular cell.
[15] V. Deretic,et al. TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis. , 2016, Developmental cell.
[16] I. Dikic,et al. PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. , 2015, Molecular cell.
[17] Yoon Ki Kim,et al. Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners , 2015, Autophagy.
[18] M. Overholtzer,et al. V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation , 2015, Autophagy.
[19] Michael I. Wilson,et al. WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1 , 2014, Molecular cell.
[20] D. Klionsky,et al. The machinery of macroautophagy , 2013, Cell Research.
[21] N. Mizushima,et al. The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes , 2012, Cell.
[22] She Chen,et al. A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate. , 2012, Molecular cell.
[23] F. Randow,et al. Galectin-8 targets damaged vesicles for autophagy to defend cells against bacterial invasion , 2011, Nature.
[24] Masaaki Komatsu,et al. Autophagy: Renovation of Cells and Tissues , 2011, Cell.
[25] Cole M. Haynes,et al. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes , 2011, Nature Cell Biology.
[26] N. Mizushima,et al. The role of Atg proteins in autophagosome formation. , 2011, Annual review of cell and developmental biology.
[27] C. Sasakawa,et al. A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens. , 2011, Cell host & microbe.
[28] N. Mizushima,et al. Autophagy in mammalian development and differentiation , 2010, Nature Cell Biology.
[29] D. Hailey,et al. Autophagy termination and lysosome reformation regulated by mTOR , 2010, Nature.
[30] S. Gygi,et al. Network organization of the human autophagy system , 2010, Nature.
[31] H. Erdjument-Bromage,et al. Processing of autophagic protein LC3 by the 20S proteasome , 2010, Autophagy.
[32] Yoshiaki Kamada,et al. Dynamics and diversity in autophagy mechanisms: lessons from yeast , 2009, Nature Reviews Molecular Cell Biology.
[33] T. Mizushima,et al. Structural Basis for Sorting Mechanism of p62 in Selective Autophagy* , 2008, Journal of Biological Chemistry.
[34] T. Noda,et al. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. , 2008, Molecular biology of the cell.
[35] F. Inagaki,et al. The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy* , 2007, Journal of Biological Chemistry.
[36] N. Mizushima,et al. Autophagy: process and function. , 2007, Genes & development.
[37] G. Bjørkøy,et al. p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy* , 2007, Journal of Biological Chemistry.
[38] Jun Onodera,et al. Autophagy Is Required for Maintenance of Amino Acid Levels and Protein Synthesis under Nitrogen Starvation* , 2005, Journal of Biological Chemistry.
[39] T. Ueno,et al. HsAtg4B/HsApg4B/Autophagin-1 Cleaves the Carboxyl Termini of Three Human Atg8 Homologues and Delipidates Microtubule-associated Protein Light Chain 3- and GABAA Receptor-associated Protein-Phospholipid Conjugates* , 2004, Journal of Biological Chemistry.
[40] T. Ueno,et al. LC3 conjugation system in mammalian autophagy , 2004, The International Journal of Biochemistry & Cell Biology.
[41] M. Komatsu,et al. Human Apg3p/Aut1p Homologue Is an Authentic E2 Enzyme for Multiple Substrates, GATE-16, GABARAP, and MAP-LC3, and Facilitates the Conjugation of hApg12p to hApg5p* , 2002, The Journal of Biological Chemistry.
[42] T. Ueno,et al. The Human Homolog of Saccharomyces cerevisiae Apg7p Is a Protein-activating Enzyme for Multiple Substrates Including Human Apg12p, GATE-16, GABARAP, and MAP-LC3* , 2001, The Journal of Biological Chemistry.
[43] Takeshi Noda,et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing , 2000, The EMBO journal.
[44] Michael D. George,et al. A protein conjugation system essential for autophagy , 1998, Nature.
[45] D. Klionsky,et al. Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. , 2000, Annual review of biochemistry.