Thermodynamics of swelling. Preparation and application of some composite, monosized polymer particles

The thermodynamic equations describing the equilibrium swelling of polymer, oligomer and polymer/oligomer particles are reviewed. The phenomenon of phase separation during swelling is discussed. Methods for preparation of monodisperse composite particles are described and the particle composition is discussed in terms of various relevant parameters. It is shown that crosslinked polymer particles may swell by a core and shell mechan sm which may increase the rate of swelling in the second step as compared to non-crosslinked part cles. Biochemical and biomedical applications of different composite particles are described.

[1]  A. Skjeltorp.  Colloidal crystals in magnetic fluid , 1984 .

[2]  A. Skjeltorp.  One- and two-dimensional crystallization of magnetic holes , 1983 .

[3]  M. Wellons,et al.  High swelling of latex particles without the utilization of swelling agents , 1983 .

[4]  Lennart Söderberg,et al.  Monodisperse polymer particles — a step forward for chromatography , 1983, Nature.

[5]  R. Wilson,et al.  Artefact peaks in particle size distributions measured by the electrical sensing zone (coulter counter) method , 1983 .

[6]  A. Rembaum,et al.  Cell labeling and magnetic separation by means of immunoreagents based on polyacrolein microspheres. , 1982, Journal of immunological methods.

[7]  F. K. Hansen,et al.  Kinetics and mechanism of vinyl chloride polymerization , 1981 .

[8]  J. Ugelstad,et al.  Swelling of oligomer-polymer particles. New methods of preparation , 1980 .

[9]  J. Ugelstad.  Swelling capacity of aqueous dispersions of oligomer and polymer substances and mixtures thereof , 1978 .

[10]  F. K. Hansen,et al.  Emulsion polymerization of styrene with sodium hexadecyl sulphate/hexadecanol mixtures as emulsifiers. Initiation in monomer droplets , 1974 .

[11]  J. L. Gardon.  Emulsion polymerization. VI. Concentration of monomers in latex particles , 1968 .

[12]  W. R. Krigbaum,et al.  Phase equilibria in polymer–liquid 1–liquid 2 systems , 1954 .

[13]  S. Kaizerman,et al.  Swelling of latex particles , 1954 .

[14]  P. Flory,et al.  STATISTICAL MECHANICS OF CROSS-LINKED POLYMER NETWORKS II. SWELLING , 1943 .

[15]  K. Nustad,et al.  Hydrophilic monodisperse particles as solid-phase material in immunoassays: comparison of shell-and-core particles with compact particles. , 1984, European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.