Profiling the Antimalarial Mechanism of Artemisinin by Identifying Crucial Target Proteins
暂无分享,去创建一个
Liwei Gu | Jigang Wang | Jiayun Chen | Chengchao Xu | P. Gao | Lingyun Dai | Liting Xu | Jianyou Wang | Yin Kwan Wong | Chen Wang | Huimin Zhang | Peng Gao
[1] Philip E. Johnson,et al. DNA binding by the antimalarial compound artemisinin , 2022, Scientific reports.
[2] Li Dai,et al. Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA , 2021, Military Medical Research.
[3] T. Efferth,et al. Multi-omics approaches to improve malaria therapy. , 2021, Pharmacological research.
[4] F. Guillonneau,et al. Comprehensive Analysis of Transcript and Protein Relative Abundance During Blood Stages of Plasmodium falciparum Infection. , 2021, Journal of proteome research.
[5] C. Amaratunga,et al. Triple Artemisinin-Based Combination Therapies for Malaria - A New Paradigm? , 2020, Trends in parasitology.
[6] Jianbin Zhang,et al. Advances in the research on the targets of anti-malaria actions of artemisinin , 2020, Pharmacology & Therapeutics.
[7] D. Fidock,et al. Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria. , 2020, Annual review of microbiology.
[8] S. Charman,et al. System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion , 2020, bioRxiv.
[9] Q. Lei,et al. Activity-based protein profiling: Recent advances in medicinal chemistry. , 2020, European journal of medicinal chemistry.
[10] Kayla Sylvester,et al. RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection , 2019, mBio.
[11] J. Yates,et al. The interactome of 2-Cys peroxiredoxins in Plasmodium falciparum , 2019, Scientific Reports.
[12] P. Nordlund,et al. Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA). , 2019, Annual review of biochemistry.
[13] S. Krishna,et al. A Temporizing Solution to "Artemisinin Resistance". , 2019, The New England journal of medicine.
[14] Arun Sharma,et al. Docking predictions based Plasmodium falciparum phosphoethanolamine methyl transferase inhibitor identification and in-vitro antimalarial activity analysis , 2019, BMC Chemistry.
[15] P. Nordlund,et al. Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay , 2019, Science Translational Medicine.
[16] Marcel Deponte,et al. Tyrosine substitution of a conserved active‐site histidine residue activates Plasmodium falciparum peroxiredoxin 6 , 2018, Protein science : a publication of the Protein Society.
[17] E. Ashley,et al. Malaria , 2018, The Lancet.
[18] D. Wirth,et al. Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum , 2017, Cell.
[19] S. Meshnick,et al. Unpacking 'Artemisinin Resistance'. , 2017, Trends in pharmacological sciences.
[20] Jigang Wang,et al. Nonradioactive quantification of autophagic protein degradation with L-azidohomoalanine labeling , 2017, Nature Protocols.
[21] Terry K. Smith,et al. Edinburgh Research Explorer Plasmodium Falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death , 2022 .
[22] V. Barton,et al. A Click Chemistry‐Based Proteomic Approach Reveals that 1,2,4‐Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile , 2016, Angewandte Chemie.
[23] J. Hemingway,et al. Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7 , 2016, Proceedings of the National Academy of Sciences.
[24] Bin Liu,et al. Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum , 2015, Nature Communications.
[25] Scott Emrich,et al. A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria , 2015, Nature.
[26] S. Nair,et al. Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi , 2015, Scientific Reports.
[27] D. Kwiatkowski,et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. , 2014, The New England journal of medicine.
[28] Choukri Ben Mamoun,et al. Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission , 2013, Proceedings of the National Academy of Sciences.
[29] P. Nordlund,et al. Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay , 2013, Science.
[30] S. Percário,et al. Oxidative Stress in Malaria , 2012, International journal of molecular sciences.
[31] H. Vial,et al. Glycerophospholipid acquisition in Plasmodium - a puzzling assembly of biosynthetic pathways. , 2010, International journal for parasitology.
[32] B. Meunier,et al. Heme as trigger and target for trioxane-containing antimalarial drugs. , 2010, Accounts of chemical research.
[33] H. Vial,et al. Exploring metabolomic approaches to analyse phospholipid biosynthetic pathways in Plasmodium , 2010, Parasitology.
[34] Choukri Ben Mamoun,et al. Targeting the lipid metabolic pathways for the treatment of malaria , 2009, Drug development research.
[35] M. Fukuda,et al. Evidence of artemisinin-resistant malaria in western Cambodia. , 2008, The New England journal of medicine.
[36] G. Pessi,et al. Disruption of the Plasmodium falciparum PfPMT Gene Results in a Complete Loss of Phosphatidylcholine Biosynthesis via the Serine-Decarboxylase-Phosphoethanolamine-Methyltransferase Pathway and Severe Growth and Survival Defects* , 2008, Journal of Biological Chemistry.
[37] S. Kano,et al. Roles of 1‐Cys peroxiredoxin in haem detoxification in the human malaria parasite Plasmodium falciparum , 2005, The FEBS journal.
[38] S. Müller. Redox and antioxidant systems of the malaria parasite Plasmodium falciparum , 2004, Molecular microbiology.
[39] S. Krishna,et al. Artemisinins: mechanisms of action and potential for resistance. , 2004, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[40] G. Pessi,et al. A pathway for phosphatidylcholine biosynthesis in Plasmodium falciparum involving phosphoethanolamine methylation. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[41] K. Becker,et al. Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions. , 2004, International journal for parasitology.
[42] S. Müller,et al. 2-Cys peroxiredoxin PfTrx-Px1 is involved in the antioxidant defence of Plasmodium falciparum. , 2003, Molecular and biochemical parasitology.
[43] S. Kano,et al. Disruption of the Plasmodium falciparum 2‐Cys peroxiredoxin gene renders parasites hypersensitive to reactive oxygen and nitrogen species , 2003, FEBS letters.
[44] H. D. del Portillo,et al. Malaria parasites contain two identical copies of an elongation factor 1 alpha gene. , 1998, Molecular and biochemical parasitology.
[45] W. Trager,et al. Human malaria parasites in continuous culture. , 1976, Science.
[46] Edward W. Tate,et al. Activity-Based Protein Profiling for the Study of Parasite Biology. , 2019, Current topics in microbiology and immunology.