Components of gut bacteria as immunomodulators.

[1]  F. Meng,et al.  Lipopolysaccharide (LPS)-induced Macrophage Activation and Signal Transduction in the Absence of Src-Family Kinases Hck, Fgr, and Lyn , 1997, The Journal of experimental medicine.

[2]  T. van der Poll,et al.  Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration. , 1997, Journal of immunology.

[3]  P. Ferrara,et al.  Detection and biochemical characteristics of the receptor for complexes of soluble CD14 and bacterial lipopolysaccharide. , 1997, Journal of immunology.

[4]  Jiahuai Han,et al.  Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation , 1997, Nature.

[5]  H. Flad,et al.  Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes , 1997, Infection and immunity.

[6]  H. Flad,et al.  Lipopolysaccharide‐binding protein mediates CD14‐independent intercalation of lipopolysaccharide into phospholipid membranes , 1996, FEBS letters.

[7]  David Baltimore,et al.  NF-κB: Ten Years After , 1996, Cell.

[8]  R. Dziarski,et al.  Differential activation of extracellular signal-regulated kinase (ERK) 1, ERK2, p38, and c-Jun NH2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan. , 1996, The Journal of infectious diseases.

[9]  T. Kirkland,et al.  CD14 Is a Cell-activating Receptor for Bacterial Peptidoglycan* , 1996, The Journal of Biological Chemistry.

[10]  A. DeFranco,et al.  Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[11]  Yi-Ping Jin,et al.  Peptidoglycan induces transcription and secretion of TNF-alpha and activation of lyn, extracellular signal-regulated kinase, and rsk signal transduction proteins in mouse macrophages. , 1995, Journal of immunology.

[12]  T. Hunter,et al.  Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus , 1995, Current Biology.

[13]  H. Flad,et al.  Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein , 1995, Infection and immunity.

[14]  D. Golenbock,et al.  CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide , 1995, The Journal of experimental medicine.

[15]  M. Kelley,et al.  Identification of a Lipopolysaccharide Binding Domain in CD14 between Amino Acids 57 and 64 (*) , 1995, The Journal of Biological Chemistry.

[16]  M. Ernst,et al.  Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14 , 1995, Infection and immunity.

[17]  C. Eckerskorn,et al.  Soluble lipopolysaccharide receptor (CD14) is released via two different mechanisms from human monocytes and CD14 transfectants , 1995, European journal of immunology.

[18]  H. Flad,et al.  Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures , 1994, Infection and immunity.

[19]  N. Reiner,et al.  CD14-dependent activation of protein kinase C and mitogen-activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide. , 1994, Journal of immunology.

[20]  M. Wurfel,et al.  Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS , 1994, The Journal of experimental medicine.

[21]  M. Glauser,et al.  Mode of action of anti-lipopolysaccharide-binding protein antibodies for prevention of endotoxemic shock in mice. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[22]  J. Randolph,et al.  Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells. , 1994, The Journal of biological chemistry.

[23]  Y. Uehara,et al.  Lipopolysaccharide‐induced cytokine production in human monocytes: Role of tyrosine phosphorylation in transmembrane signal transduction , 1994, European journal of immunology.

[24]  E. Vellenga,et al.  G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. A study of the molecular mechanisms involved in inflammatory cytokine expression. , 1994, The Journal of biological chemistry.

[25]  T. Kirikae,et al.  Bacterial endotoxin: molecular relationships of structure to activity and function , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  R. Ulevitch,et al.  Recognition of endotoxin by cells leading to transmembrane signaling. , 1994, Current opinion in immunology.

[27]  K. Takayama,et al.  Monomeric Re lipopolysaccharide from Escherichia coli is more active than the aggregated form in the Limulus amebocyte lysate assay and in inducing Egr-1 mRNA in murine peritoneal macrophages. , 1994, The Journal of biological chemistry.

[28]  M. Lotz,et al.  Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes. , 1993, Journal of immunology.

[29]  H. Northoff,et al.  Prevention of endotoxin-induced monokine release by human low- and high-density lipoproteins and by apolipoprotein A-I , 1993, Infection and immunity.

[30]  R. Ulevitch,et al.  Analysis of lipopolysaccharide binding by CD14. , 1993, The Journal of biological chemistry.

[31]  M. Freeman,et al.  Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin. , 1993, The Journal of biological chemistry.

[32]  R. Davis,et al.  The mitogen-activated protein kinase signal transduction pathway. , 1993, The Journal of biological chemistry.

[33]  M. Read,et al.  Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells. , 1993, The Journal of biological chemistry.

[34]  M. Kastowsky,et al.  Phase behavior, supramolecular structure, and molecular conformation of lipopolysaccharide. , 1993, Immunobiology.

[35]  P. Baeuerle,et al.  Nuclear factor kappa B, a mediator of lipopolysaccharide effects. , 1993, Immunobiology.

[36]  R. Ulevitch,et al.  Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[37]  S. Akira,et al.  Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[38]  G. Skjåk‐Braek,et al.  The involvement of CD14 in stimulation of cytokine production by uronic acid polymers , 1993, European journal of immunology.

[39]  B. Finlay,et al.  Soluble CD14 participates in the response of cells to lipopolysaccharide , 1992, The Journal of experimental medicine.

[40]  Wendy L. Freedman,et al.  THE EXPANSION RATE AND SIZE OF THE UNIVERSE , 1992 .

[41]  R. Ulevitch,et al.  Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14- mediated pathway , 1992, The Journal of experimental medicine.

[42]  A. DeFranco,et al.  Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. , 1992, The Journal of biological chemistry.

[43]  K. Kato,et al.  Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein , 1992, The Journal of experimental medicine.

[44]  I. Azuma.  Review: inducer of cytokines in vivo: overview of field and romurtide experience. , 1992, International journal of immunopharmacology.

[45]  Alan D. Roberts,et al.  Structural basis of capacity of lipoarabinomannan to induce secretion of tumor necrosis factor , 1992, Infection and immunity.

[46]  A. R. Nogare,et al.  Southwestern Internal Medicine Conference: Septic Shock , 1991 .

[47]  R. Dziarski.  Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking. , 1991, The Journal of biological chemistry.

[48]  J. Höltje,et al.  Isolation and separation of the glycan strands from murein of Escherichia coli by reversed-phase high-performance liquid chromatography. , 1990, Analytical biochemistry.

[49]  R. Ulevitch,et al.  Structure and function of lipopolysaccharide binding protein. , 1990, Science.

[50]  R. Ulevitch,et al.  CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. , 1990, Science.

[51]  R. Strieter,et al.  Dynamics of dibutyryl cyclic AMP- and prostaglandin E2-mediated suppression of lipopolysaccharide-induced tumor necrosis factor alpha gene expression , 1989, Infection and immunity.

[52]  A. Waage,et al.  Cytokine regulation of interleukin 6 production by human endothelial cells. , 1989, Cellular immunology.

[53]  J. Maller,et al.  Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II , 1988, Nature.

[54]  U. Schwarz,et al.  The composition of the murein of Escherichia coli. , 1988, The Journal of biological chemistry.

[55]  R. Cotran,et al.  Identification of an inducible endothelial-leukocyte adhesion molecule. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[56]  H. Friedman,et al.  Immunobiology and Immunopharmacology of Bacterial Endotoxins , 1987 .

[57]  C. Nathan,et al.  Secretory products of macrophages. , 1987, The Journal of clinical investigation.

[58]  W. J. Cromartie,et al.  Acute And Chronic Inflammation Induced By Peptidoglycan Structures And Polysaccharide Complexes , 1986 .

[59]  S. Wright,et al.  Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide , 1986, The Journal of experimental medicine.

[60]  A. Tanaka,et al.  Chemical structure and biological activity relationship of bacterial cell walls and muramyl peptides. , 1986, Federation proceedings.

[61]  E. Rietschel,et al.  Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities. , 1985, European journal of biochemistry.

[62]  E. Günther,et al.  Mitogenic stimulation of murine spleen cells: relation to susceptibility to Salmonella infection , 1977, Infection and immunity.

[63]  R. Menzel,et al.  Mutation of amino acids 39-44 of human CD14 abrogates binding of lipopolysaccharide and Escherichia coli. , 1997, European journal of biochemistry.

[64]  R R Schumann,et al.  Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification. , 1996, Current topics in microbiology and immunology.

[65]  P. Brandtzaeg.  Significance and pathogenesis of septic shock. , 1996, Current topics in microbiology and immunology.

[66]  P. Baeuerle,et al.  Function and activation of NF-kappa B in the immune system. , 1994, Annual review of immunology.

[67]  B. Lindner,et al.  Molecular structure of lipid A, the endotoxic center of bacterial lipopolysaccharides. , 1994, Advances in carbohydrate chemistry and biochemistry.

[68]  H. Loppnow.  LPS, recIL1 and smooth muscle cell-IL1 activate vascular cells by specific mechanisms. , 1994, Progress in clinical and biological research.

[69]  J. Rüschoff,et al.  The role of TNF in tumour growth and metastasis. , 1993, Research in immunology.

[70]  S. Wright,et al.  Multiple receptors for endotoxin. , 1991, Current opinion in immunology.

[71]  E. Schrinner.  Surface structures of microorganisms and their interactions with the mammalian host , 1988 .

[72]  W. J. Cromartie,et al.  Lipopolysaccharide-Induced Recurrence of Arthritis Initiated by Peptidoglycan-Polysaccharide , 1986 .

[73]  E. Mihich.  Immunological approaches to cancer therapeutics , 1982 .