Formylpeptide receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
暂无分享,去创建一个
Marc Parmentier | Charles N. Serhan | Takao Shimizu | Ji Ming Wang | Magnus Bäck | François Boulay | Nan Chiang | Sven-Erik Dahlén | Claes Dahlgren | Jeffrey M. Drazen | Jilly F. Evans | Craig Gerard | Philip M. Murphy | Mark T. Quinn | G. Enrico Rovati | Richard D. Ye | Takehiko Yokomizo | J. Drazen | S. Dahlén | M. Parmentier | Takao Shimizu | Ji Ming Wang | R. Ye | C. Serhan | N. Chiang | P. Murphy | M. Bäck | T. Yokomizo | C. Dahlgren | C. Gerard | F. Boulay | G. Rovati | M. Quinn
[1] C. Turck,et al. Tethered Ligand Library for Discovery of Peptide Agonists (*) , 1995, The Journal of Biological Chemistry.
[2] J. Unitt,et al. Discovery of small molecule human FPR1 receptor antagonists. , 2009, Bioorganic & medicinal chemistry letters.
[3] R. Lefkowitz,et al. Specific receptor sites for chemotactic peptides on human polymorphonuclear leukocytes. , 1977, Proceedings of the National Academy of Sciences of the United States of America.
[4] A. Khlebnikov,et al. High-Throughput Screening for Small-Molecule Activators of Neutrophils: Identification of Novel N-Formyl Peptide Receptor Agonists , 2007, Molecular Pharmacology.
[5] Masaaki Muramatsu,et al. Polymorphisms of the formylpeptide receptor gene (FPR1) and susceptibility to stomach cancer in 1531 consecutive autopsy cases. , 2011, Biochemical and biophysical research communications.
[6] C. Serhan,et al. Resolvin D1 binds human phagocytes with evidence for proresolving receptors , 2010, Proceedings of the National Academy of Sciences.
[7] A. Gilman,et al. Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin , 1984, Cell.
[8] A. Gilman,et al. G proteins: transducers of receptor-generated signals. , 1987, Annual review of biochemistry.
[9] M. Perretti,et al. Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. , 2006, Blood.
[10] M. Parmentier,et al. F2L, a Peptide Derived from Heme-Binding Protein, Chemoattracts Mouse Neutrophils by Specifically Activating Fpr2, the Low-Affinity N-Formylpeptide Receptor1 , 2007, The Journal of Immunology.
[11] A. Toporik,et al. A Novel Peptide Agonist of Formyl-Peptide Receptor-Like 1 (ALX) Displays Anti-Inflammatory and Cardioprotective Effects , 2009, Journal of Pharmacology and Experimental Therapeutics.
[12] H. Shin,et al. Association analysis of formyl peptide receptor 2 (FPR2) polymorphisms and Aspirin exacerbated respiratory diseases , 2012, Journal of Human Genetics.
[13] C. Serhan,et al. HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Anti-Inflammatory Actions of Lipoxin A 4 Stable Analogs Are Demonstrable in Human Whole Blood: Modulation of Leukocyte Adhesion Molecules and Inhibition of Neutrophil-Endothelial Interactions , 2016 .
[14] Marc Parmentier,et al. Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses. , 2006, Cytokine & growth factor reviews.
[15] C. Serhan,et al. Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction. , 1995, Biochemistry.
[16] E. Grazzini,et al. A truncated form of CKβ8‐1 is a potent agonist for human formyl peptide‐receptor‐like 1 receptor , 2004, British journal of pharmacology.
[17] R. Ye,et al. Normal Cell Surface Expression and Selective Loss of Functions Resulting from Phe110 to Ser and Cys126 to Trp Substitutions in the Formyl Peptide Receptor , 2004, Immunological investigations.
[18] R. Liskamp,et al. N-Terminal Residues of the Chemotaxis Inhibitory Protein of Staphylococcus aureus Are Essential for Blocking Formylated Peptide Receptor but Not C5a Receptor , 2004, The Journal of Immunology.
[19] J. Wang,et al. Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors , 2000, Inflammation Research.
[20] Jian Huang,et al. Cutting Edge: A Critical Role for the G Protein-Coupled Receptor mFPR2 in Airway Inflammation and Immune Responses , 2010, The Journal of Immunology.
[21] Y. Yamamoto,et al. Inhibitory effects of spinorphin, a novel endogenous regulator, on chemotaxis, O2- generation, and exocytosis by N-formylmethionyl-leucyl-phenylalanine (FMLP)-stimulated neutrophils. , 1997, Biochemical pharmacology.
[22] M. Perretti,et al. Stimulus-dependent specificity for annexin 1 inhibition of the inflammatory nociceptive response: the involvement of the receptor for formylated peptides , 2004, Pain.
[23] P. Murphy,et al. Amyloid-β Induces Chemotaxis and Oxidant Stress by Acting at Formylpeptide Receptor 2, a G Protein-coupled Receptor Expressed in Phagocytes and Brain* , 2001, The Journal of Biological Chemistry.
[24] R. Ye,et al. Pharmacological Characterization of a Novel Nonpeptide Antagonist for Formyl Peptide Receptor-Like 1 , 2007, Molecular Pharmacology.
[25] R. Ye,et al. Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. , 2003, Blood.
[26] W. Gong,et al. T21/DP107, A synthetic leucine zipper-like domain of the HIV-1 envelope gp41, attracts and activates human phagocytes by using G-protein-coupled formyl peptide receptors. , 1999, Journal of immunology.
[27] R. Eddy,et al. Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19. , 1992, Genomics.
[28] W. Gong,et al. Synthetic peptide MMK‐1 is a highly specific chemotactic agonist for leukocyte FPRL1 , 2001, Journal of leukocyte biology.
[29] E. Prossnitz,et al. Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor. , 1992, Biochemical and biophysical research communications.
[30] C. Wennerås,et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are Antagonists that Preferentially Inhibit Activity Triggered Through the Formyl Peptide Receptor , 2007, Inflammation.
[31] P. Ward,et al. The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli. , 1975, Journal of immunology.
[32] N. Lehman,et al. Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2. , 2006, Blood.
[33] Guixiu Shi,et al. CD38: an ecto-enzyme at the crossroads of innate and adaptive immune responses. , 2007, Advances in experimental medicine and biology.
[34] M. Parmentier,et al. Identification and characterization of an endogenous chemotactic ligand specific for FPRL2 , 2005, The Journal of experimental medicine.
[35] S. Sentellas,et al. Lack of activity of 15‐epi‐lipoxin A4 on FPR2/ALX and CysLT1 receptors in interleukin‐8‐driven human neutrophil function , 2013, Clinical and experimental immunology.
[36] M. Jutila,et al. Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1 , 2012, Journal of Molecular Modeling.
[37] T. Feuerstein,et al. Differential effects of KATP channel blockers on [3H]-noradrenaline overflow after short- and long-term exposure to (+)-oxaprotiline or desipramine , 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.
[38] M. Perretti,et al. Aspirin-triggered 15-epi-lipoxin A4 signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation , 2015, International journal of cardiology.
[39] A. Stalder,et al. Biomarker‐guided clinical development of the first‐in‐class anti‐inflammatory FPR2/ALX agonist ACT‐389949 , 2017, British journal of clinical pharmacology.
[40] A. Spagnolo,et al. Lipoxin A4 Counteracts Synergistic Activation of Human Fibroblast-like Synoviocytes , 2004, International journal of immunopathology and pharmacology.
[41] J. Walters,et al. Formylpeptide receptor single nucleotide polymorphism 348T>C and its relationship to polymorphonuclear leukocyte chemotaxis in aggressive periodontitis. , 2009, Journal of periodontology.
[42] T. Takano,et al. A novel rat lipoxin A4 receptor that is conserved in structure and function , 2003, British journal of pharmacology.
[43] D. Cockayne,et al. Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo , 2001, Nature Medicine.
[44] Y. Bae,et al. Trp-Arg-Trp-Trp-Trp-Trp antagonizes formyl peptide receptor like 2-mediated signaling. , 2006, Biochemical and biophysical research communications.
[45] H. Perez,et al. Signal Transduction by the Formyl Peptide Receptor , 1995, The Journal of Biological Chemistry.
[46] F. D’Acquisto,et al. Impaired T cell activation and increased Th2 lineage commitment in Annexin‐1‐deficient T cells , 2007, European journal of immunology.
[47] P. Janmey,et al. The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide , 2004, BMC Cell Biology.
[48] P. Naccache,et al. Transport of sodium, potassium, and calcium across rabbit polymorphonuclear leukocyte membranes. Effect of chemotactic factor , 1977, The Journal of cell biology.
[49] Takao Shimizu,et al. The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo , 2006, Pharmacological Reviews.
[50] W. Gong,et al. Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. , 2001, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[51] C. Serhan,et al. Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. , 2012, The American journal of pathology.
[52] K. Wenzel-Seifert,et al. Differential inhibition of human neutrophil activation by cyclosporins A, D, and H. Cyclosporin H is a potent and effective inhibitor of formyl peptide-induced superoxide formation. , 1991, Journal of immunology.
[53] A. Kirk,et al. Human platelets exhibit chemotaxis using functional N-formyl peptide receptors. , 2005, Experimental hematology.
[54] A. Schottelius,et al. Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo. , 2004, Journal of medicinal chemistry.
[55] C. Serhan,et al. Aspirin‐triggered lipoxin A4 and lipoxin A4 up‐regulate transcriptional corepressor NAB1 in human neutrophils , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[56] Tudor I. Oprea,et al. High-Throughput Screening with HyperCyt® Flow Cytometry to Detect Small Molecule Formylpeptide Receptor Ligands , 2005, Journal of biomolecular screening.
[57] W. Gong,et al. Humanin, a Newly Identified Neuroprotective Factor, Uses the G Protein-Coupled Formylpeptide Receptor-Like-1 as a Functional Receptor1 , 2004, The Journal of Immunology.
[58] C. Dahlgren,et al. Structural Characterization and Inhibitory Profile of Formyl Peptide Receptor 2 Selective Peptides Descending from a PIP2-Binding Domain of Gelsolin , 2012, The Journal of Immunology.
[59] A. Fischman,et al. Selective inhibition of N-formylpeptide-induced neutrophil activation by carbamate-modified peptide analogues. , 1996, Biochemistry.
[60] P. Smiley,et al. Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[61] J. Werba,et al. Transcriptional regulation of the human FPR2/ALX gene: evidence of a heritable genetic variant that impairs promoter activity , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[62] W. Gong,et al. T20/DP178, an ectodomain peptide of human immunodeficiency virus type 1 gp41, is an activator of human phagocyte N-formyl peptide receptor. , 1999, Blood.
[63] T. Takano,et al. Lipoxin A4 Stable Analogs Are Potent Mimetics That Stimulate Human Monocytes and THP-1 Cells via a G-protein-linked Lipoxin A4 Receptor* , 1997, The Journal of Biological Chemistry.
[64] M. Perretti,et al. A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. , 2013, Blood.
[65] K. Wenzel-Seifert,et al. Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E. , 1993, Journal of immunology.
[66] K. Wenzel-Seifert,et al. Cyclosporin H Is a Potent and Selective Formyl Peptide Receptor Antagonist Comparison with Nt-Butoxycarbonyl-~-phenylalanyl-L-leucyl-L-phenylalanyl-1-leucyl-L-phenylalanine and Cyclosporins , 2001 .
[67] M. Hersberger,et al. No evidence for the involvement of the lipoxin A4 receptor (FPR2/ALX) gene in the susceptibility to coronary artery disease , 2012, Clinical chemistry and laboratory medicine.
[68] R. Ye,et al. Human dendritic cells express functional formyl peptide receptor‐like‐2 (FPRL2) throughout maturation , 2002, Journal of leukocyte biology.
[69] J. Varga,et al. Opposing Regulation of Interleukin-8 and NF-kB Responses by Lipoxin A4 and Serum Amyloid a via the Common Lipoxin a Receptor , 2004, International journal of immunopathology and pharmacology.
[70] J. Kwak,et al. Identification of Peptides That Antagonize Formyl Peptide Receptor-Like 1-Mediated Signaling1 , 2004, The Journal of Immunology.
[71] R. Egan,et al. Phosphatidylcholine hydrolysis by phospholipase D determines phosphatidate and diglyceride levels in chemotactic peptide-stimulated human neutrophils. Involvement of phosphatidate phosphohydrolase in signal transduction. , 1989, The Journal of biological chemistry.
[72] K. Wenzel-Seifert,et al. Defective Gi Protein Coupling in Two Formyl Peptide Receptor Mutants Associated with Localized Juvenile Periodontitis* , 2001, The Journal of Biological Chemistry.
[73] P. Murphy,et al. The Endogenous Opioid Spinorphin Blocks fMet-Leu-Phe-Induced Neutrophil Chemotaxis by Acting as a Specific Antagonist at the N-Formylpeptide Receptor Subtype FPR , 2001, The Journal of Immunology.
[74] R. Hannon,et al. Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation , 2010, The Journal of Immunology.
[75] S. Lockett,et al. Identification of Neutrophil Granule Protein Cathepsin G as a Novel Chemotactic Agonist for the G Protein-Coupled Formyl Peptide Receptor 12 , 2004, The Journal of Immunology.
[76] G. Bartolucci,et al. Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists. , 2012, Bioorganic & medicinal chemistry.
[77] A. Young,et al. Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis1 , 2002, The Journal of Immunology.
[78] T. Takenawa,et al. Role of enhanced inositol phospholipid metabolism in neutrophil activation. , 1985, Biochemical pharmacology.
[79] Anna Karlsson,et al. A Proinflammatory Peptide from Herpes Simplex Virus Type 2 Glycoprotein G Affects Neutrophil, Monocyte, and NK Cell Functions1 , 2005, The Journal of Immunology.
[80] Ji Ming Wang,et al. The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[81] J. Broach,et al. Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast , 1998, Nature Biotechnology.
[82] S. Visvikis-Siest,et al. Human formyl peptide receptor 1 C32T SNP interacts with age and is associated with blood pressure levels. , 2012, Clinica chimica acta; international journal of clinical chemistry.
[83] J. McClary,et al. Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils. , 1992, Gene.
[84] P A Ward,et al. Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli. , 1984, The Journal of biological chemistry.
[85] C B Wollheim,et al. Is cytosolic ionized calcium regulating neutrophil activation? , 1983, Science.
[86] P. Henson,et al. The sequential release of granule constitutents from human neutrophils. , 1980, Journal of immunology.
[87] Ji Ming Wang,et al. Ll-37, the Neutrophil Granule–And Epithelial Cell–Derived Cathelicidin, Utilizes Formyl Peptide Receptor–Like 1 (Fprl1) as a Receptor to Chemoattract Human Peripheral Blood Neutrophils, Monocytes, and T Cells , 2000, The Journal of experimental medicine.
[88] M. Perretti,et al. Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes. , 2006, Biochemical and biophysical research communications.
[89] S. Hinuma,et al. N-Formylated humanin activates both formyl peptide receptor-like 1 and 2. , 2004, Biochemical and biophysical research communications.
[90] L. Mcphail,et al. Measurement of phospholipid metabolism in intact neutrophils. , 2007, Methods in molecular biology.
[91] J. Woska,et al. Broad immunocytochemical localization of the formylpeptide receptor in human organs, tissues, and cells , 1998, Cell and Tissue Research.
[92] E. Prossnitz,et al. Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding. Construction and analysis of chimeric N-formyl peptide receptors. , 1993, The Journal of biological chemistry.
[93] L. Pardo,et al. Structural Determinants for the Interaction of Formyl Peptide Receptor 2 with Peptide Ligands* , 2013, The Journal of Biological Chemistry.
[94] J. Kwak,et al. Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells. , 2005, Biochemical and biophysical research communications.
[95] M. Perretti,et al. Ligand-specific conformational change of the G-protein–coupled receptor ALX/FPR2 determines proresolving functional responses , 2013, Proceedings of the National Academy of Sciences.
[96] Tudor I. Oprea,et al. A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1. , 2012, Biochemical pharmacology.
[97] G. Downey,et al. Involvement of Cytosolic Phospholipase A2 and Secretory Phospholipase A2 in Arachidonic Acid Release from Human Neutrophils1 , 2000, The Journal of Immunology.
[98] C. Dahlgren,et al. Lipoxin A4 Metabolites/Analogues from Two Commercial Sources have No Effects on TNF‐α‐mediated Priming or Activation through the Neutrophil Formyl Peptide Receptors , 2009, Scandinavian journal of immunology.
[99] Shuguang Zhang,et al. Production of a Bioengineered G-Protein Coupled Receptor of Human Formyl Peptide Receptor 3 , 2011, PloS one.
[100] P. Murphy,et al. Impaired Antibacterial Host Defense in Mice Lacking the N-formylpeptide Receptor , 1999, The Journal of experimental medicine.
[101] D. Haviland,et al. N-formylpeptide and complement C5a receptors are expressed in liver cells and mediate hepatic acute phase gene regulation , 1995, The Journal of experimental medicine.
[102] S. Marullo,et al. Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor , 2002, Nature Medicine.
[103] Jennifer E. Golden,et al. Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents. , 2006, Bioorganic & medicinal chemistry letters.
[104] R. Ye,et al. Functional Characterization of Three Mouse Formyl Peptide Receptors , 2013, Molecular Pharmacology.
[105] D. McDermott,et al. Contrasting evolution of the human leukocyte N-formylpeptide receptor subtypes FPR and FPRL1R , 2001, Genes and Immunity.
[106] W. Gong,et al. Silencing the Formylpeptide Receptor FPR by Short-Interfering RNA , 2004, Molecular Pharmacology.
[107] Ronald Anderson,et al. Activation of Human Neutrophils with Chemotactic Peptide, Opsonized Zymosan and the Calcium Ionophore A23187, But Not with a Phorbol Ester, is Accompanied by Efflux and Store-Operated Influx of Calcium , 2000, Inflammation.
[108] M. Jutila,et al. Identification of Novel Small-Molecule Agonists for Human Formyl Peptide Receptors and Pharmacophore Models of Their Recognition , 2010, Molecular Pharmacology.
[109] C. Kozak,et al. Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse. , 1998, Genomics.
[110] C. Serhan,et al. Induction of functional lipoxin A4 receptors in HL-60 cells. , 1993, Blood.
[111] C. Serhan,et al. Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. , 1992, The Journal of biological chemistry.
[112] W. Junger,et al. Circulating Mitochondrial DAMPs Cause Inflammatory Responses to Injury , 2009, Nature.
[113] A. Jesaitis,et al. Reconstitution of recombinant N‐formyl chemotactic peptide receptor with G protein , 1993, Journal of leukocyte biology.
[114] K. Hellstrand,et al. A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis. , 2001, The Journal of clinical investigation.
[115] C. Movitz,et al. Neutrophil NADPH‐oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors , 2005, Journal of leukocyte biology.
[116] W. Gong,et al. Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines. , 2000, Biochemical and biophysical research communications.
[117] U. Rescher,et al. An Annexin 1 N-Terminal Peptide Activates Leukocytes by Triggering Different Members of the Formyl Peptide Receptor Family1 , 2004, The Journal of Immunology.
[118] T. Schöneberg,et al. Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus. , 2010, Cell host & microbe.
[119] M. Tardif,et al. Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNA. , 1990, Biochemical and biophysical research communications.
[120] B. Engelhardt,et al. Ligand-induced adhesion to activated endothelium and to vascular cell adhesion molecule-1 in lymphocytes transfected with the N-formyl peptide receptor. , 1994, Journal of immunology.
[121] R. Egan,et al. Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes. , 1988, The Journal of biological chemistry.
[122] Hae‐Sim Park,et al. The genetic association of the FPRL1 promoter polymorphism with chronic urticaria in a Korean population. , 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[123] C. Mackay,et al. Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells , 1996, The Journal of cell biology.
[124] R. Lefkowitz,et al. The oligopeptide chemotactic factor receptor on human polymorphonuclear leukocyte membranes exists in two affinity states. , 1982, Biochemical and biophysical research communications.
[125] S. Whittemore,et al. Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia , 1995, Journal of Neuroimmunology.
[126] B. Premack,et al. Proinflammatory Proteases Liberate a Discrete High-Affinity Functional FPRL1 (CCR12) Ligand from CCL2312 , 2007, The Journal of Immunology.
[127] T. Usdin,et al. Reduced Fear Memory and Anxiety-like Behavior in Mice Lacking Formylpeptide Receptor 1 , 2011, Behavior genetics.
[128] U. Francke,et al. A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family. , 1992, The Journal of biological chemistry.
[129] R. Ye,et al. The Immunosuppressant Cyclosporin A Antagonizes Human Formyl Peptide Receptor through Inhibition of Cognate Ligand Binding1 , 2006, The Journal of Immunology.
[130] Hugh R. Brady,et al. Cutting Edge: Lipoxins Rapidly Stimulate Nonphlogistic Phagocytosis of Apoptotic Neutrophils by Monocyte-Derived Macrophages1 , 2000, The Journal of Immunology.
[131] M. Perretti,et al. Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci: Receptor-Dependent Actions , 2012, Arteriosclerosis, thrombosis, and vascular biology.
[132] W. Gong,et al. Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation. , 1999, Journal of immunology.
[133] M. Wenlock,et al. Lead optimisation of pyrazoles as novel FPR1 antagonists. , 2012, Bioorganic & medicinal chemistry letters.
[134] F. Yarovinsky,et al. Mouse Cathelin-Related Antimicrobial Peptide Chemoattracts Leukocytes Using Formyl Peptide Receptor-Like 1/Mouse Formyl Peptide Receptor-Like 2 as the Receptor and Acts as an Immune Adjuvant1 , 2005, The Journal of Immunology.
[135] R. Ye,et al. Identification of Formyl Peptides from Listeria monocytogenes and Staphylococcus aureus as Potent Chemoattractants for Mouse Neutrophils1 , 2008, The Journal of Immunology.
[136] C. Serhan,et al. Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-α Secretion from Human T Cells 1 , 2003, The Journal of Immunology.
[137] K. Krause,et al. Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation. , 1985, The Journal of clinical investigation.
[138] W. Gong,et al. Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis. , 2013, The Journal of clinical investigation.
[139] S. Ryu,et al. A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils. , 1997, Journal of immunology.
[140] M. Tardif,et al. The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors. , 1990, Biochemistry.
[141] A. Jesaitis,et al. Chemotaxis of chinese hamster ovary cells expressing the human neutrophil formyl peptide receptor: role of signal transduction molecules and alpha5beta1 integrin. , 1998, Journal of cell science.
[142] C. Serhan,et al. Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation , 2000, The Journal of experimental medicine.
[143] M. Billah,et al. Phospholipase C and phospholipase D are activated independently of each other in chemotactic peptide‐stimulated human neutrophils , 1993, Journal of leukocyte biology.
[144] C. Serhan,et al. Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[145] Huiping Jiang,et al. Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors* , 1996, The Journal of Biological Chemistry.
[146] I. Williams,et al. Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium. , 2003, American journal of physiology. Cell physiology.
[147] C. Serhan,et al. Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor , 1994, The Journal of experimental medicine.
[148] A. Sharma,et al. Single nucleotide polymorphisms of the N-formyl peptide receptor in localized juvenile periodontitis. , 1999, Journal of periodontology.
[149] M. Perretti,et al. Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. , 2001, The American journal of pathology.
[150] E. Leonard,et al. A series of six ligands for the human formyl peptide receptor: tetrapeptides with high chemotactic potency and efficacy. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[151] P. Cuatrecasas,et al. Receptor-mediated internalization of fluorescent chemotactic peptide by human neutrophils. , 1979, Science.
[152] R. Ammendola,et al. Distinct Signaling Cascades Elicited by Different Formyl Peptide Receptor 2 (FPR2) Agonists , 2013, International journal of molecular sciences.
[153] Marc Parmentier,et al. International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family , 2009, Pharmacological Reviews.
[154] P. Murphy,et al. The HIV-1 cell entry inhibitor T-20 potently chemoattracts neutrophils by specifically activating the N-formylpeptide receptor. , 2000, Biochemical and biophysical research communications.
[155] F. Boulay,et al. Human mitochondria‐derived N‐formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes‐derived peptides preferentially activate FPR , 2005, European journal of immunology.
[156] Philip M Murphy,et al. Formyl-peptide receptors revisited. , 2002, Trends in immunology.
[157] W. Gong,et al. Expression of functional formyl peptide receptors by human astrocytoma cell lines , 2000, Journal of Neuroimmunology.
[158] N. Ferreirós,et al. Heterologously expressed formyl peptide receptor 2 (FPR2/ALX) does not respond to lipoxin A₄. , 2013, Biochemical pharmacology.
[159] W. Gong,et al. Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes , 2012, Scientific Reports.
[160] C. Dahlgren,et al. The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2* , 2001, The Journal of Biological Chemistry.
[161] F Sherman,et al. Methionine or not methionine at the beginning of a protein , 1985, BioEssays : news and reviews in molecular, cellular and developmental biology.
[162] G. Barish,et al. N-Formylpeptides Induce Two Distinct Concentration Optima for Mouse Neutrophil Chemotaxis by Differential Interaction with Two N-Formylpeptide Receptor (Fpr) Subtypes , 1999, The Journal of experimental medicine.
[163] Clemencia Pinilla,et al. Selective Agonists and Antagonists of Formylpeptide Receptors: Duplex Flow Cytometry and Mixture-Based Positional Scanning Libraries , 2013, Molecular Pharmacology.
[164] J. Walters,et al. Neutrophil formylpeptide receptor single nucleotide polymorphism 348T>C in aggressive periodontitis. , 2009, Journal of periodontology.
[165] T. Takano,et al. Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors , 1997, The Journal of experimental medicine.
[166] B. Levy,et al. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a ‘stop’ signaling switch for aspirin‐triggered lipoxin A4 , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[167] R. D. Mellon,et al. Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants. , 2002, Biochemical pharmacology.
[168] Zigmond Sh. Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors. , 1977 .
[169] V. Gerke,et al. A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. , 2000, Molecular cell.
[170] A. Jesaitis,et al. 399 MUTATIONS OF F110 AND C126 OF THE FORMYL PEPTIDE RECEPTOR INTERFERE WITH G-PROTEIN COUPLING AND CHEMOTAXIS. , 2003, Journal of Investigative Medicine.
[171] A. Day,et al. Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophils. , 1982, Biochemistry.
[172] Ji Ming Wang,et al. Peptide Receptor Chemotactic Agonist for Mouse Formyl Trp-Lys-Tyr-Met-Val-d-Met Is a Potent The Synthetic Peptide and , 2000 .
[173] H. Carp. Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils , 1982, The Journal of experimental medicine.
[174] Tudor I. Oprea,et al. Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30. , 2009, Current topics in medicinal chemistry.
[175] C. Clish,et al. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo , 1999 .
[176] J. Varga,et al. Lipoxin A4 Inhibits IL-1β-Induced IL-6, IL-8, and Matrix Metalloproteinase-3 Production in Human Synovial Fibroblasts and Enhances Synthesis of Tissue Inhibitors of Metalloproteinases1 , 2000, The Journal of Immunology.
[177] S. Su,et al. N36, a synthetic N-terminal heptad repeat domain of the HIV-1 envelope protein gp41, is an activator of human phagocytes. , 2000, Clinical immunology.
[178] C. Dahlgren,et al. N-Formyl Peptide Receptor 3 (FPR3) Departs from the Homologous FPR2/ALX Receptor with Regard to the Major Processes Governing Chemoattractant Receptor Regulation, Expression at the Cell Surface, and Phosphorylation , 2011, The Journal of Biological Chemistry.
[179] C. Serhan,et al. Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. , 2001, The American journal of pathology.
[180] J. V. van Strijp,et al. A New Staphylococcal Anti-Inflammatory Protein That Antagonizes the Formyl Peptide Receptor-Like 11 , 2006, The Journal of Immunology.
[181] P. Kubes,et al. Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation , 2010, Science.
[182] J. A. Radding,et al. Further studies on the structural requirements for synthetic peptide chemoattractants. , 1980, Biochemistry.
[183] C. Serhan,et al. Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction , 1996, The Journal of experimental medicine.
[184] R. Ye,et al. A Novel Nonpeptide Ligand for Formyl Peptide Receptor-Like 1 , 2004, Molecular Pharmacology.
[185] Tudor I. Oprea,et al. Integration of Virtual Screening with High-Throughput Flow Cytometry to Identify Novel Small Molecule Formylpeptide Receptor Antagonistss⃞ , 2005, Molecular Pharmacology.
[186] A. Narang,et al. Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant‐stimulated HL‐60 cells , 2008, Journal of leukocyte biology.
[187] S. Zigmond,et al. The structure-activity relations of synthetic peptides as chemotactic factors and inducers of lysosomal secretion for neutrophils , 1976, The Journal of experimental medicine.
[188] S. Wahl,et al. N-formylmethionyl peptides as chemoattractants for leucocytes. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[189] M. Perretti,et al. Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms. , 2003, Blood.
[190] W. Gong,et al. A Seven-transmembrane, G Protein–coupled Receptor, FPRL1, Mediates the Chemotactic Activity of Serum Amyloid A for Human Phagocytic Cells , 1999, The Journal of experimental medicine.
[191] W. Gong,et al. A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R. , 1999, Blood.