Asymmetric organocatalysis in total synthesis--a trial by fire.

Covering: 2007 to 2009 This review covers the most recent applications of organocatalysis in the synthesis of natural products and non-natural biologically active molecules. Our aim is to showcase how organocatalytic reactions have overcome some of their teething problems and how they frequently offer very practical solutions to long-standing synthetic challenges. 161 references are cited.

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