Intensive behavioral treatment for children with autism: four-year outcome and predictors.

Twenty-four children with autism were randomly assigned to a clinic-directed group, replicating the parameters of the early intensive behavioral treatment developed at UCLA, or to a parent-directed group that received intensive hours but less supervision by equally well-trained supervisors. Outcome after 4 years of treatment, including cognitive, language, adaptive, social, and academic measures, was similar for both groups. After combining groups, we found that 48% of all children showed rapid learning, achieved average posttreatment scores, and at age 7, were succeeding in regular education classrooms. Treatment outcome was best predicted by pretreatment imitation, language, and social responsiveness. These results are consistent with those reported by Lovaas and colleagues (Lovaas, 1987; McEachin, Smith, & Lovaas, 1993).

[1]  Gina Green,et al.  Cost–benefit estimates for early intensive behavioral intervention for young children with autism—general model and single state case , 1998 .

[2]  S. Harris,et al.  Age and IQ at Intake as Predictors of Placement for Young Children with Autism: A Four- to Six-Year Follow-Up , 2000, Journal of autism and developmental disorders.

[3]  T. Achenbach,et al.  Manual for the Teacher's Report Form and 1991 Profile , 1991 .

[4]  Dona G. Icabone,et al.  Vineland Adaptive Behavior Scales , 1999 .

[5]  Susan A. Sullivan,et al.  Leiter International Performance Scale–Revised , 1998 .

[6]  S. Sheinkopf,et al.  Home-Based Behavioral Treatment of Young Children with Autism , 1998, Journal of autism and developmental disorders.

[7]  Benjamin B. Lahey,et al.  Advances in Clinical Child Psychology , 1980, Advances in Clinical Child Psychology.

[8]  David Wechsler,et al.  Manual for the Wechsler intelligence scale for children , 1974 .

[9]  C. Lord,et al.  Follow-up of two-year-olds referred for possible autism. , 1995, Journal of child psychology and psychiatry, and allied disciplines.

[10]  C. Lord,et al.  The role of age at assessment, developmental level, and test in the stability of intelligence scores in young autistic children , 1989, Journal of autism and developmental disorders.

[11]  Janet A. Welsh,et al.  Social relationship deficits. , 1997 .

[12]  O. I. Lovaas,et al.  Long-term outcome for children with autism who received early intensive behavioral treatment. , 1993, American journal of mental retardation : AJMR.

[13]  M. Guralnick,et al.  The Effectiveness of Early Intervention. , 1997 .

[14]  Tristram Smith,et al.  Randomized Trial of Intensive Early Intervention for Children With Pervasive Developmental Disorder , 2000 .

[15]  Tristram H. Smith,et al.  Intensive Behavioral Treatment at School for 4- to 7-Year-Old Children with Autism , 2002, Behavior modification.

[16]  S. McConnell,et al.  Interventions to Facilitate Social Interaction for Young Children with Autism: Review of Available Research and Recommendations for Educational Intervention and Future Research , 2002, Journal of autism and developmental disorders.

[17]  Sandra L. Harris,et al.  Preschool Education Programs for Children With Autism , 1993 .

[18]  P. J. Krantz,et al.  Age at intervention and treatment outcome for autistic children in a comprehensive intervention program , 1985 .

[19]  M. Sigman,et al.  Relations Among Joint Attention, Amount of Intervention and Language Gain in Autism , 2004, Journal of autism and developmental disorders.

[20]  O. I. Lovaas,et al.  Teaching Developmentally Disabled Children: The Me Book , 1981 .

[21]  C. Corsello,et al.  Early Intervention in Autism , 2005 .

[22]  Gina Green,et al.  A comparison of intensive behavior analytic and eclectic treatments for young children with autism. , 2005, Research in developmental disabilities.

[23]  Tristram Smitha,et al.  Parent-directed , intensive early intervention for children with pervasive developmental disorder , 2000 .

[24]  E. Schopler,et al.  Relation of behavioral treatment to "normal functioning": comment on Lovaas. , 1989, Journal of consulting and clinical psychology.

[25]  長尾 圭造 Reynell Developmental Language Scales(R.D.L.S.)の紹介と日本での実施の試み , 1981 .

[26]  G. Baird,et al.  Infants with autism: an investigation of empathy, pretend play, joint attention, and imitation. , 1997, Developmental psychology.

[27]  D. Lachar The Personality Inventory for Children. , 1982 .

[28]  S Eldevik,et al.  Teaching children with autism to initiate and sustain cooperative play. , 2000, Research in developmental disabilities.

[29]  Tristram Smith,et al.  Intensive Behavioral Treatment for Young Autistic Children , 1988 .

[30]  A. Bondy,et al.  The Picture Exchange Communication System , 1994, Seminars in speech and language.

[31]  Tristram H. Smith Comments on Replication and Evaluation of Outcome. , 1993 .

[32]  L. Koegel,et al.  Pivotal Response Intervention II: Preliminary Long-Term Outcome Data , 1999 .

[33]  David W. Hosmer,et al.  Best subsets logistic regression , 1989 .

[34]  F. Gresham,et al.  Early Intervention Project: Can Its Claims Be Substantiated and Its Effects Replicated? , 1998, Journal of autism and developmental disorders.

[35]  Tristram H. Smith,et al.  The UCLA Young Autism Project: A Reply to Gresham and MacMillan , 1997 .

[36]  Stephen R. Anderson,et al.  Intensive home-based early intervention with autistic children. , 1987 .

[37]  M. Wiznitzer,et al.  AIDS and the Nervous System , 1988, Neurology.

[38]  P. Mundy,et al.  Normal versus High-Functioning Status in Children with Autism. , 1993 .

[39]  Tristram H. Smith,et al.  Effects of Low-Intensity Behavioral Treatment for Children with Autism and Mental Retardation , 2006, Journal of autism and developmental disorders.

[40]  L M LaVange,et al.  Infant Health and Development Program for low birth weight, premature infants: program elements, family participation, and child intelligence. , 1992, Pediatrics.

[41]  O. I. Lovaas,et al.  Behavioral treatment and normal educational and intellectual functioning in young autistic children. , 1987, Journal of consulting and clinical psychology.

[42]  Tristram H. Smith,et al.  Intensive behavioral treatment for preschoolers with severe mental retardation and pervasive developmental disorder. , 1997, American journal of mental retardation : AJMR.

[43]  F. Volkmar,et al.  Language regression in childhood. , 2001, Pediatric neurology.

[44]  Dc Washington Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .

[45]  Mary Jane Weiss,et al.  Differential rates of skill acquisition and outcomes of early intensive behavioral intervention for autism , 1999 .

[46]  Progress and outcomes for children with autism receiving parent-managed intensive interventions , 2002 .

[47]  O. I. Lovaas,et al.  Clarifying comments on the young autism study: reply to Schopler, Short, and Mesibov. , 1989, Journal of consulting and clinical psychology.

[48]  J. Birnbrauer,et al.  The Murdoch Early Intervention Program After 2 Years , 1993, Behaviour Change.

[49]  R. Koegel,et al.  Assessing and training teachers in the generalized use of behavior modification with autistic children. , 1977, Journal of applied behavior analysis.

[50]  C. Lord,et al.  A follow-up study of high-functioning autistic children. , 1992, Journal of child psychology and psychiatry, and allied disciplines.

[51]  Patricia Howlin,et al.  Children with Autism and Asperger Syndrome: A Guide for Practitioners and Carers , 1999 .

[52]  E. Carr,et al.  Reducing behavior problems through functional communication training. , 1985, Journal of applied behavior analysis.

[53]  H. Peak Mental Measurement of Preschool Children with a Guide for the Administration of the Merrill-Palmer Scale of Mental Tests. , 2022 .

[54]  J Q Simmons,et al.  Some generalization and follow-up measures on autistic children in behavior therapy. , 1973, Journal of applied behavior analysis.

[55]  H. Goldstein,et al.  Generalized language learning by children with severe mental retardation: effects of peers' expressive modeling. , 1989, Journal of applied behavior analysis.

[56]  S. Harris,et al.  Changes in cognitive and Language functioning of Preschool children with autism , 1991, Journal of autism and developmental disorders.

[57]  M. Charlop,et al.  Teaching autistic children conversational speech using video modeling. , 1989, Journal of applied behavior analysis.

[58]  T. Achenbach Child Behavior Checklist. , 2000 .

[59]  B. Hart,et al.  Incidental teaching of language in the preschool. , 1975, Journal of applied behavior analysis.

[60]  R. Tuchman,et al.  Regression in pervasive developmental disorders: seizures and epileptiform electroencephalogram correlates. , 1997, Pediatrics.

[61]  Teaching Children with Autism, Strategies for Initiating Positive Interactions and Improving Learning Opportunities , 1996 .

[62]  T. Giles Handbook of effective psychotherapy , 1993 .

[63]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[64]  Gina Green,et al.  Behavioral intervention for young children with autism: A manual for parents and professionals. , 1996 .

[65]  N. Bayley Bayley Scales of Infant Development , 1999 .

[66]  R. Barkley,et al.  Treatment of childhood disorders , 1998 .

[67]  R. D. Wirt Multidimensional description of child personality : a manual for the personality inventory for children , 1977 .