Mixture Modeling for Digital Mammogram Display and Analysis

We have devised a mammogram modeling system which greatly simplifies the development of, and can improve the accuracy and consistency of, computer-aided display and analysis algorithms for digital mammography. Our system segments the five major components of a mammogram: background, uncompressed-fat, fat, dense, and muscle. Differences in the amount and distribution of these components account for much of the variation between mammograms. Via segmentation, the corresponding variations are isolated; automated algorithms can consider the components independently or adapt their parameters based on component-specific statistics.

[1]  S. Pizer,et al.  Intensity ridge and widths for tubular object segmentation and description , 1996, Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis.

[2]  J. Wolfe,et al.  Mammographic features and breast cancer risk: effects with time, age, and menopause status. , 1995, Journal of the National Cancer Institute.

[3]  N Karssemeijer,et al.  Automated classification of parenchymal patterns in mammograms. , 1998, Physics in medicine and biology.