In Vivo Fluorescence Spectroscopy and Imaging for Oncological Applications

Keywords: Photomedicine group Reference LPAS-ARTICLE-1998-003View record in Web of Science Record created on 2007-07-20, modified on 2016-08-08

[1]  A G Yodh,et al.  Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: analytic solutions and applications. , 1996, Applied optics.

[2]  R. Rava,et al.  SPECTROSCOPIC DIAGNOSIS OF COLONIC DYSPLASIA , 1991, Photochemistry and photobiology.

[3]  P. Monnier,et al.  Optimizing light dosimetry in photodynamic therapy of early stage carcinomas of the esophagus using fluorescence spectroscopy , 1996, Lasers in surgery and medicine.

[4]  A E Profio,et al.  Detection of early lung cancer using low dose Photofrin II. , 1990, Chest.

[5]  Stefan Andersson-Engels,et al.  The use of time-resolved fluorescence for diagnosis of atherosclerotic plaque and malignant tumours , 1990 .

[6]  T. Smyrk,et al.  Duodenoesophageal reflux and the development of esophageal adenocarcinoma in rats. , 1992, Surgery.

[7]  R. Alfano,et al.  Laser induced fluorescence spectroscopy from native cancerous and normal tissue , 1984 .

[8]  T. Hasan,et al.  Treatment of ovarian cancer with photodynamic therapy and immunoconjugates in a murine ovarian cancer model. , 1996, British Journal of Cancer.

[9]  Kevin M. Smith,et al.  EVALUATION OF NEW BENZOPORPHYRIN DERIVATIVES WITH ENHANCED PDT EFFICACY* , 1995, Photochemistry and photobiology.

[10]  H Szmacinski,et al.  Fluorescence lifetime imaging. , 1992, Analytical biochemistry.

[11]  Wei R. Chen,et al.  Detection and characterization of chemical-induced abnormal tissue and rat tumors at different stages using fluorescence spectroscopy , 1996, Photonics West.

[12]  W. Stahl,et al.  Porphyrins Preferentially Accumulate in a Melanoma Following Intravenous Injection of 5-Aminolevulinic Acid , 1997, Biological chemistry.

[13]  J Moan,et al.  5‐Aminolevulinic acid‐based photodynamic therapy , 1997, Cancer.

[14]  Anthony J. Durkin,et al.  Comparison of methods to determine chromophore concentrations from fluorescence spectra of turbid samples , 1995, Lasers in surgery and medicine.

[15]  M Motamedi,et al.  Evaluation of spectral correction techniques for fluorescence measurements on pigmented lesions in vivo. , 1996, Journal of photochemistry and photobiology. B, Biology.

[16]  K Svanberg,et al.  Photodynamic therapy of non‐melanoma malignant tumours of the skin using topical δ‐amino levulinic acid sensitization and laser irradiation , 1994, The British journal of dermatology.

[17]  L. Guillou,et al.  Clinical evaluation of a method for detecting superficial transitional cell carcinoma of the bladder by light‐induced fluorescence of protoporphyrin IX following topical application of 5‐aminolevulinic acid: Preliminary results , 1997, Lasers in surgery and medicine.

[18]  Thomas S. Mang,et al.  Fluorescence detection of tumors: studies on the early diagnosis of microscopic lesions in preclinical and clinical studies , 1991, Photonics West - Lasers and Applications in Science and Engineering.

[19]  Anthony J. Durkin,et al.  Optically Dilute, Absorbing, and Turbid Phantoms for Fluorescence Spectroscopy of Homogeneous and Inhomogeneous Samples , 1993 .

[20]  Spectral characterization of the benzoporphyrin derivative monoacid ring-A photoproduct formed in fetal calf solutions during irradiation with 694 nm continuous-wave radiation. , 1996, Journal of photochemistry and photobiology. B, Biology.

[21]  B. Wilson,et al.  Monte Carlo modeling of light propagation in highly scattering tissues. I. Model predictions and comparison with diffusion theory , 1989, IEEE Transactions on Biomedical Engineering.

[22]  W Lohmann,et al.  Significance of autofluorescence for the optical demarcation of field cancerisation in the upper aerodigestive tract. , 1997, Acta oto-laryngologica.

[23]  H. Iishi,et al.  3339 Diagnosis of early gastric cancers by an endoscopic autofluorescence imaging system. , 1997 .

[24]  F. Docchio.  Ocular fluorometry: Principles, fluorophores, instrumentation, and clinical applications , 1989, Lasers in surgery and medicine.

[25]  J. Reguła,et al.  Sensitization and photodynamic therapy (PDT) of gastrointestinal tumors with 5-aminolaevulinic acid (ALA) induced protoporphyrin IX (PPIX). A pilot study. , 1995, Neoplasma.

[26]  K. Svanberg,et al.  Laser-induced fluorescence in malignant and normal tissue in mice injected with two different carotenoporphyrins. , 1994, British Journal of Cancer.

[27]  C. Fontolliet,et al.  7,12‐Dimethylbenz[a]anthracene‐induced ‘early’ squamous cell carcinoma in the Golden Syrian hamster: evaluation of an animal model and comparison with ‘early’ forms of human squamous cell carcinoma in the upper aero‐digestive tract , 1996, International journal of experimental pathology.

[28]  M J Gray,et al.  Use of hematoporphyrin derivative in detection and management of cervical cancer. , 1967, American journal of obstetrics and gynecology.

[29]  J E Kaufman,et al.  Photoradiation therapy for the treatment of malignant tumors. , 1978, Cancer research.

[30]  J. Kennedy,et al.  Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. , 1990, Journal of photochemistry and photobiology. B, Biology.

[31]  J Moan,et al.  Build-up of esterified aminolevulinic-acid-derivative-induced porphyrin fluorescence in normal mouse skin. , 1996, Journal of Photochemistry and Photobiology. B: Biology.

[32]  Michael S. Feld,et al.  A model for extraction of diagnostic information from laser induced fluorescence spectra of human artery wall , 1989 .

[33]  M. Gray,et al.  Hematoporphyrin derivative for detection and management of cancer , 1967, Cancer.

[34]  Stefan Andersson-Engels,et al.  Fluorescence diagnostics of head and neck cancer utilizing oral administration of delta-amino levulinic acid , 1994, Other Conferences.

[35]  Henryk Szmacinski,et al.  Fluorescence lifetime-based sensing and imaging. , 1995, Sensors and actuators. B, Chemical.

[36]  Q. Peng,et al.  5‐Aminolevulinic Acid‐Based Photodynamic Therapy: Principles and Experimental Research , 1997, Photochemistry and photobiology.

[37]  A. M. Olsen,et al.  The use of a derivative of hematoporphyrin in tumor detection. , 1961 .

[38]  L. Lilge,et al.  Photodynamic Therapy of 9L Gliosarcoma with Liposome‐Delivered Photofrin , 1997, Photochemistry and photobiology.

[39]  H Stepp,et al.  Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. , 1996, The Journal of urology.

[40]  M. Korbelik,et al.  Photofrin accumulation in malignant and host cell populations of various tumours. , 1996, British Journal of Cancer.

[41]  Donald L. Weaver,et al.  Three-dimensional reconstruction by confocal laser scanning microscopy in routine pathologic specimens of benign and malignant lesions of the human breast , 1997, Histochemistry and Cell Biology.

[42]  T J Dougherty,et al.  Fluorescence detection of tumors early diagnosis of microscopic lesions in preclinical studies , 1993, Cancer.

[43]  Brian C. Wilson,et al.  Confocal fluorescence microscopy, microspectrofluorimetry, and modeling studies of laser-induced fluorescence endoscopy (LIFE) of human colon tissue , 1997, Photonics West - Biomedical Optics.

[44]  Martin Kriegmair,et al.  CELLULAR FLUORESCENCE OF THE ENDOGENOUS PHOTOSENSITIZER PROTOPORPHYRIN IX FOLLOWING EXPOSURE TO 5‐AMINOLEVULINIC ACID , 1995, Photochemistry and photobiology.

[45]  B Palcic,et al.  Detection of squamous cell cancer and pre-cancerous lesions by imaging of tissue autofluorescence in the hamster cheek pouch model. , 1992, Surgical oncology.

[46]  Anthony J. Durkin,et al.  Relation between fluorescence spectra of dilute and turbid samples. , 1994, Applied optics.

[47]  R. Anderson,et al.  Iontophoretic delivery of ALA provides a quantitative model for ALA pharmacokinetics and PpIX phototoxicity in human skin. , 1997, The Journal of investigative dermatology.

[48]  Christopher J. Frank,et al.  Raman spectroscopy of normal and diseased human breast tissues. , 1995, Analytical chemistry.

[49]  G. Rao,et al.  Potential applications of lifetime-based, phase-modulation fluorimetry in bioprocess and clinical monitoring. , 1995, Trends in biotechnology.

[50]  R M Cothren,et al.  Detection of dysplasia at colonoscopy using laser-induced fluorescence: a blinded study. , 1996, Gastrointestinal endoscopy.

[51]  H. Pass,et al.  Photodynamic therapy in oncology: mechanisms and clinical use. , 1993, Journal of the National Cancer Institute.

[52]  H Stepp,et al.  Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity. , 1996, American journal of surgery.

[53]  M. Soloway.  Editorial Comment: Detection of Early Bladder Cancer by 5-Aminolevulinic Acid Induced Porphyrin Fluorescence , 1996 .

[54]  P. Lenz.  Endoscopic fluorescence detector , 1988 .

[55]  R. Sroka,et al.  In vivo fluorescence kinetics of porphyrins following intravesical instillation of 5-aminolaevulinic acid in normal and tumour-bearing rat bladders. , 1997, Journal of photochemistry and photobiology. B, Biology.

[56]  J. Kennedy,et al.  The possible role of ionic species in selective biodistribution of photochemotherapeutic agents toward neoplastic tissue. , 1990, Journal of photochemistry and photobiology. B, Biology.

[57]  R Birngruber,et al.  Low-coherence optical tomography in turbid tissue: theoretical analysis. , 1995, Applied optics.

[58]  D. Vernon,et al.  Endogenous porphyrin distribution induced by 5-aminolaevulinic acid in the tissue layers of the gastrointestinal tract. , 1993, Journal of photochemistry and photobiology. B, Biology.

[59]  J. H. Kinsey,et al.  Detection of hematoporphyrin fluorescence during fiberoptic bronchoscopy to localize early bronchogenic carcinoma. , 1978, Mayo Clinic proceedings.

[60]  T. Hasan,et al.  In Vivo Tissue Characterization Using Environmentally Sensitive Fluorochromes , 1996 .

[61]  Steven L. Jacques,et al.  Fluorescence of normal and cancerous brain tissues: the excitation/emission matrix , 1994, Photonics West - Lasers and Applications in Science and Engineering.

[62]  Calum MacAulay,et al.  Laser-induced fluorescence spectroscopy at endoscopy: tissue optics, Monte Carlo modeling, and in vivo measurements , 1995 .

[63]  H. Reinhold,et al.  Reoxygenation of tumours in "sandwich" chambers. , 1979, European journal of cancer.

[64]  V. I. Polsachev,et al.  Fluorescent diagnostics of human gastric cancer and sodium fluorescein accumulation in experimental gastric cancer in rats. , 1993, Cancer letters.

[65]  E J BALDES,et al.  FURTHER EVALUATION OF THE USE OF HEMATOPORPHYRIN DERIVATIVE AS A NEW AID FOR THE ENDOSCOPIC DETECTION OF MALIGNANT DISEASE. , 1964, Diseases of the chest.

[66]  B. Wilson,et al.  Monte Carlo modeling of light propagation in highly scattering tissues. II. Comparison with measurements in phantoms , 1989, IEEE Transactions on Biomedical Engineering.

[67]  Michael R Hamblin,et al.  On the mechanism of the tumour-localising effect in photodynamic therapy. , 1994, Journal of photochemistry and photobiology. B, Biology.

[68]  M. Zellweger,et al.  An optical phantom with tissue-like properties in the visible for use in PDT and fluorescence spectroscopy. , 1997, Physics in medicine and biology.

[69]  M W Berns,et al.  Ability of specific monoclonal antibodies and conventional antisera conjugated to hematoporphyrin to label and kill selected cell lines subsequent to light activation. , 1985, Cancer research.

[70]  K König,et al.  Time-resolved in-vivo fluorescence of photosensitizing porphyrins. , 1993, Journal of photochemistry and photobiology. B, Biology.

[71]  J. Mizeret.  Cancer detection by endoscopic frequency-domain fluorescence lifetime imaging , 1998 .

[72]  Daniel Braichotte,et al.  Clinical pharmacokinetic studies of tetra(meta‐hydroxyphenyl)chlorin in squamous cell carcinoma by fluorescence spectroscopy at 2 wavelengths , 1995, International journal of cancer.

[73]  H. van den Bergh,et al.  Antibody–fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice , 1991, Cancer.

[74]  Elie E. Rebeiz,et al.  Diagnostic fluorescence spectroscopy of oral mucosa , 1995, Photonics West.

[75]  H. Bergh,et al.  Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice. , 1994, Cancer research.

[76]  T Takemura,et al.  TUMOR‐LOCALIZING FLUORESCENT DIAGNOSTIC AGENTS WITHOUT PHOTOTOXICITY , 1994, Photochemistry and photobiology.

[77]  C. Depeursinge,et al.  Clinical imaging fluorescence apparatus for the endoscopic photodetection of early cancers by use of Photofrin II. , 1997, Applied optics.

[78]  O. Cussenot,et al.  Argon laser induced autofluorescence may distinguish between normal and tumor human urothelial cells: a microspectrofluorimetric study. , 1996, The Journal of urology.

[79]  D. Kessel,et al.  LIPOPROTEIN‐MEDIATED DISTRIBUTION OF N‐ASPARTYL CHLORIN‐E6 IN THE MOUSE , 1992, Photochemistry and photobiology.

[80]  N Ramanujam,et al.  In vivo diagnosis of cervical intraepithelial neoplasia using 337-nm-excited laser-induced fluorescence. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[81]  Steven L. Jacques,et al.  In vivo fluorescence spectroscopy and imaging of human skin tumors. , 1995 .

[82]  Leon Lagnado,et al.  The retina , 1999, Current Biology.

[83]  T. Hasan,et al.  Mechanism of photosensitization by microsphere-bound chlorin e6 in human bladder carcinoma cells. , 1991, Cancer research.

[84]  A E Profio,et al.  Digital background subtraction for fluorescence imaging. , 1986, Medical physics.

[85]  J. M. Nauta,et al.  In vivo fluorescence kinetics and localisation of aluminum phthalocyanine disulphonate in an autologous tumour model. , 1996, British Journal of Cancer.

[86]  R. Lambert,et al.  Long-term survival after photodynamic therapy for esophageal cancer. , 1995, Gastroenterology.

[87]  G. Papanicolaou,et al.  A microfluorometric scanning method for the detection of cancer cells in smears of exfoliated cells , 1952, Cancer.

[88]  Hubert van den Bergh,et al.  Endoscopic frequency-domain fluorescence lifetime imaging for clinical cancer photodetection: apparatus design , 1995, Photonics West.

[89]  Sigrid Avrillier,et al.  Laser-induced autofluorescence diagnosis of tumors , 1997 .

[90]  J. H. Kinsey,et al.  Endoscopic system for simultaneous visual examination and electronic detection of fluorescence. , 1980, The Review of scientific instruments.

[91]  P. Sharp,et al.  Fundus imaging in patients with cataract: role for a variable wavelength scanning laser ophthalmoscope. , 1995, The British journal of ophthalmology.

[92]  T J Dougherty,et al.  Fluorescence bronchoscopy for detection of lung cancer. , 1979, Chest.

[93]  A. Profio,et al.  Laser excited fluorescence of hematoporphyrin derivative for diagnosis of cancer , 1984 .

[94]  J. H. Kinsey,et al.  Detection and localization of In situ carcinoma of the bladder with hematoporphyrin derivative. , 1982, Mayo Clinic proceedings.

[95]  Patrice Jichlinski,et al.  Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results , 1995, Other Conferences.

[96]  C. Relakis,et al.  Laser-induced fluorescence detection of malignancies in the female genital tract via their natural emission and hypocrellin (HA) probing. , 1997, Journal of photochemistry and photobiology. B, Biology.

[97]  W Lohmann,et al.  Native fluorescence of the cervix uteri as a marker for dysplasia and invasive carcinoma. , 1989, European journal of obstetrics, gynecology, and reproductive biology.

[98]  T. Muto,et al.  The evolution of cancer of the colon and rectum , 1974, Cancer.

[99]  H E Savage,et al.  Native cellular fluorescence can identify changes in epithelial thickness in-vivo in the upper aerodigestive tract. , 1995, American journal of surgery.

[100]  J C Kennedy,et al.  Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy. , 1992, Journal of photochemistry and photobiology. B, Biology.

[101]  S. Contini,et al.  Vital staining of oesophagus in patients with head and neck cancer: still a worthwhile procedure. , 1991, The Italian journal of gastroenterology.

[102]  P. McDonnell,et al.  Laser-induced fluorescence during photorefractive keratectomy: a method for controlling epithelial removal. , 1997, American journal of ophthalmology.

[103]  S. Schantz,et al.  Polarization Filter for Biomedical Tissue Optical Imaging , 1997, Photochemistry and photobiology.

[104]  H. Kato,et al.  Early detection of lung cancer by means of hematoporphyrin derivative fluorescence and laser photoradiation. , 1985, Clinics in chest medicine.

[105]  Daniel Braichotte,et al.  Clinical Evaluation of the Cutaneous Phototoxicity of 5,10,15,20‐Tetra (m‐hydroxyphenyl)chlorin , 1998, Photochemistry and photobiology.

[106]  W. Star,et al.  In vivo fluorescence and photodynamic activity of zinc phthalocyanine administered in liposomes. , 1994, British Journal of Cancer.

[107]  H. Nauta,et al.  Difficulties in diagnosis of supratentorial gliomas by CAT scan. , 1979, Journal of neurology, neurosurgery, and psychiatry.

[108]  L. Salford,et al.  Ten-year survival among patients with supratentorial astrocytomas grade III and IV. , 1988, Journal of neurosurgery.

[109]  R M Cothren,et al.  Laser-induced fluorescence microscopy of normal colon and dysplasia in colonic adenomas: implications for spectroscopic diagnosis. , 1995, The American journal of gastroenterology.

[110]  D I McLean,et al.  Reconstruction of in vivo skin autofluorescence spectrum from microscopic properties by Monte Carlo simulation. , 1997, Journal of photochemistry and photobiology. B, Biology.

[111]  A E Profio,et al.  A feasibility study of the use of fluorescence bronchoscopy for localization of small lung tumours. , 1977, Physics in medicine and biology.

[112]  R Marchesini,et al.  Light-induced fluorescence spectroscopy of adenomas, adenocarcinomas and non-neoplastic mucosa in human colon. I. In vitro measurements. , 1992, Journal of photochemistry and photobiology. B, Biology.

[113]  L. Lilge,et al.  Real time light induced fluorescence endoscopy (life) in the gastrointestinal (GI) tract , 1997 .

[114]  A. Goetz,et al.  Photodynamic therapy with 5-aminolaevulinic acid-induced porphyrins of an amelanotic melanoma in vivo. , 1997, Journal of photochemistry and photobiology. B, Biology.

[115]  J. Mourant,et al.  Ultraviolet and visible spectroscopies for tissue diagnostics: fluorescence spectroscopy and elastic-scattering spectroscopy. , 1997, Physics in medicine and biology.

[116]  M. Snell,et al.  Hematoporphyrin derivative: a possible aid in the diagnosis and therapy of carcinoma of the bladder. , 1976, The Journal of urology.

[117]  I Itzkan,et al.  Rapid multiexcitation fluorescence spectroscopy system for in vivo tissue diagnosis. , 1996, Applied optics.

[118]  M. Sivak,et al.  Methylene blue selectively stains intestinal metaplasia in Barrett's esophagus. , 1996, Gastrointestinal endoscopy.

[119]  Distribution of aluminum phthalocyanine disulfonate in an oral squamous cell carcinoma model. In vivo fluorescence imaging compared with ex vivo analytical methods. , 1997, Photochemistry and photobiology.

[120]  W. S. Andrus,et al.  Cystoscopic fluorescence detector for photodetection of bladder carcinoma with hematoporphyrin derivative. , 1984, The Journal of urology.

[121]  Craig Gardner,et al.  Propagation of fluorescent light , 1997, Lasers in surgery and medicine.

[122]  H Anholt,et al.  Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture. , 1997, Cancer research.

[123]  Hubert van den Bergh,et al.  Clinical comparison of the pharmacokinetics of m-THPC and Photofrin II as observed by light-induced fluorescence , 1994, Other Conferences.

[124]  P. Monnier,et al.  Further appraisal of PDI and PDT of early squamous cell carcinomas of the pharynx, oesophagus and bronchi , 1992 .

[125]  B. Overholt,et al.  Photodynamic therapy with porfimer sodium versus thermal ablation therapy with Nd:YAG laser for palliation of esophageal cancer: a multicenter randomized trial. , 1995, Gastrointestinal endoscopy.

[126]  Steven L. Jacques,et al.  How photobleaching affects dosimetry and fluorescence monitoring of PDT in turbid media , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[127]  K Svanberg,et al.  Fluorescence diagnosis and photochemical treatment of diseased tissue using lasers: Part I. , 1989, Analytical chemistry.

[128]  Haishan Zeng,et al.  SPECTROSCOPIC AND MICROSCOPIC CHARACTERISTICS OF HUMAN SKIN AUTOFLUORESCENCE EMISSION , 1995, Photochemistry and photobiology.

[129]  S. Majumder,et al.  Breast cancer diagnosis using N2 laser excited autofluorescence spectroscopy , 1997, Lasers in surgery and medicine.

[130]  Stuart L. Marcus,et al.  Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): current clinical and development status. , 1996 .

[131]  C. Chabannon,et al.  Photophysical and Redox Properties of a Series of Phthalocyanines: Relation with Their Photodynamic Activities on TF‐1 and Daudi Leukemic Cells , 1996, Photochemistry and photobiology.

[132]  H. Iishi,et al.  Diagnosis of early gastric cancers by an endoscopic autofluorescence imaging system: Study of red and white color autofluorescence , 1998 .

[133]  K Svanberg,et al.  Fluorescence studies of hematoporphyrin derivative in normal and malignant rat tissue. , 1986, Cancer research.

[134]  G. Moore,et al.  The clinical use of fluorescein in neurosurgery; the localization of brain tumors. , 1948, Journal of neurosurgery.

[135]  R Baumgartner,et al.  Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer. , 1996, British journal of urology.

[136]  R. Rava,et al.  Analytical model for extracting intrinsic fluorescence in turbid media. , 1993, Applied optics.

[137]  F. Figge,et al.  Cancer detection and therapy. III. Affinity of lymphatic tissues for hematoporphyrin. , 1953, Bulletin of the School of Medicine.

[138]  S. C. Chang,et al.  5‐aminolevulinic acid (ALA)‐induced protoporphyrin IX fluorescence and photodynamic effects in the rat bladder: An in vivo study comparing oral and intravesical ALA administration , 1997, Lasers in surgery and medicine.

[139]  K. Kincade.  Optical diagnostics image tissues and tumors , 1996 .

[140]  M. Ochsner.  Photophysical and photobiological processes in the photodynamic therapy of tumours. , 1997, Journal of photochemistry and photobiology. B, Biology.

[141]  L. Kiemeney,et al.  Prognostic factors in superficial bladder cancer. A review. , 1992, European urology.

[142]  K Svanberg,et al.  FLUORESCENCE IMAGING AND POINT MEASUREMENTS OF TISSUE: APPLICATIONS TO THE DEMARCATION OF MALIGNANT TUMORS AND ATHEROSCLEROTIC LESIONS FROM NORMAL TISSUE , 1991, Photochemistry and photobiology.

[143]  J Moan,et al.  Pharmacokinetic studies on 5-aminolevulinic acid-induced protoporphyrin IX accumulation in tumours and normal tissues. , 1997, Cancer Letters.

[144]  D. Slaughter,et al.  “Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin , 1953, Cancer.

[145]  A Coldman,et al.  Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. , 1998, Chest.

[146]  Joris Kloek,et al.  Prodrugs of 5‐Aminolevullinic Acid for Photodynamic Therapy , 1996, Photochemistry and photobiology.

[147]  B Palcic,et al.  Detection and localization of early lung cancer by imaging techniques. , 1993, Chest.

[148]  Hubert van den Bergh,et al.  In-vivo measurement of fluorescence bleaching of meso-tetra hydroxy phenyl chlorin (mTHPC) in the esophagus and the oral cavity , 1995, European Conference on Biomedical Optics.

[149]  A E Profio,et al.  Laser fluorescence bronchoscope for localization of occult lung tumors. , 1979, Medical physics.

[150]  J Hanania,et al.  The effect of EDTA and serum on endogenous porphyrin accumulation and photodynamic sensitization of human K562 leukemic cells. , 1992, Cancer letters.

[151]  F. D. de Gruijl,et al.  Dose-time dependency of tumor formation by chronic UV exposure. , 1983, Photochemistry and photobiology.

[152]  F. Figge,et al.  Use of hematoporphyrin fluorescence in biliary and cancer surgery. , 1955, The American surgeon.

[153]  Stefan Andersson-Engels,et al.  In vivo fluorescence in clinical oncology: fundamental and practical issues , 1992 .

[154]  Britton Chance,et al.  Precision localization of hidden absorbers in body tissues with phased-array optical systems , 1996 .

[155]  D. W. Rogers,et al.  Fluorescence photography: a diagnostic tool for the surgical setting. , 1990, Journal of biological photography.

[156]  R. Webb,et al.  In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast. , 1995, The Journal of investigative dermatology.

[157]  Robert R. Alfano,et al.  Ultraviolet excited fluorescence spectra from non-malignant and malignant tissues of the gynecological tract , 1992 .

[158]  P. Disaia,et al.  Selective photosensitizer localization in the human endometrium after intrauterine application of 5-aminolevulinic acid. , 1996, American journal of obstetrics and gynecology.

[159]  Pratt Jh,et al.  HEMATOPORPHYRINE DERIVATIVE FOR DETECTION OF CERVICAL CANCER. , 1964 .

[160]  R. Alfano,et al.  Raman, fluorescence, and time-resolved light scattering as optical diagnostic techniques to separate diseased and normal biomedical media. , 1992, Journal of photochemistry and photobiology. B, Biology.

[161]  Branko Palcic,et al.  Detection of lung cancer by ratio fluorometry with and without Photofrin II , 1990, Photonics West - Lasers and Applications in Science and Engineering.

[162]  K. Svanberg,et al.  Laser‐induced fluorescence studies of normal and malignant tumour tissue of rat following intravenous injection of δ‐amino levulinic acid , 1997, Lasers in surgery and medicine.

[163]  J R Leonard,et al.  Hematoporphyrin fluorescence: An aid in diagnosis of malignant neoplasms , 1971, The Laryngoscope.

[164]  L. Deckelbaum,et al.  Laser-induced fluorescence spectroscopy of human colonic mucosa. Detection of adenomatous transformation. , 1990, Gastroenterology.

[165]  P. Nowell.  Mechanisms of tumor progression. , 1986, Cancer research.

[166]  G. Kuhnle,et al.  In vivo kinetics and spectra of 5-aminolaevulinic acid-induced fluorescence in an amelanotic melanoma of the hamster. , 1994, British Journal of Cancer.

[167]  Y Wang,et al.  Fluorescence endoscopic imaging of human colonic adenomas. , 1996, Gastroenterology.

[168]  Y F Li,et al.  Characteristic autofluorescence for cancer diagnosis and its origin. , 1987, Lasers in surgery and medicine.

[169]  B. Wilson,et al.  Development of an In Vivo Raman Spectroscopic System for Diagnostic Applications , 1997 .

[170]  A. Michael-Titus,et al.  Distribution and Excretion of Radiolabeled Temoporfin in a Murine Tumor Model , 1996, Photochemistry and photobiology.

[171]  M S Patterson,et al.  Imaging of fluorescent yield and lifetime from multiply scattered light reemitted from random media. , 1997, Applied optics.

[172]  K. I. Pravdenko,et al.  In vivo optical coherence tomography of human skin microstructure , 1994, Other Conferences.

[173]  R Baumgartner,et al.  Pharmacokinetics of 5-aminolevulinic-acid-induced porphyrins in tumour-bearing mice. , 1996, Journal of photochemistry and photobiology. B, Biology.

[174]  D. Kessel,et al.  Side effects and photosensitization of human tissues after aminolevulinic acid. , 1997, The Journal of surgical research.

[175]  Thanassis Papaioannou,et al.  Intraoperative metastases detection by laser-induced fluorescence spectroscopy , 1991, Photonics West - Lasers and Applications in Science and Engineering.

[176]  C. L. Hutchinson,et al.  Fluorescence and Absorption Contrast Mechanisms for Biomedical Optical Imaging Using Frequency‐Domain Techniques , 1997, Photochemistry and photobiology.

[177]  Richard P. Haugland,et al.  Handbook of fluorescent probes and research chemicals , 1996 .

[178]  Christian D. Depeursinge,et al.  Photodetection of early cancer in the upper aerodigestive tract and the bronchi using photofrin II and colorectal adenocarcinoma with fluoresceinated monoclonal antibodies , 1991, MedTech.

[179]  P. Monnier,et al.  Photofrin II Pharmacokinetics and Optical Dosing in Tissue: Apparatus and Clinical Measurements for the Pharynx, Esophagus, and Tracheobronchial Tree , 1991 .

[180]  Robert R. Alfano,et al.  Optical spectroscopic diagnosis of cancer and normal breast tissues: erratum , 1990 .

[181]  S. Kimel,et al.  In vivo damage to chorioallantoic membrane blood vessels by porphycene-induced photodynamic therapy. , 1995, Journal of photochemistry and photobiology. B, Biology.

[182]  K D Paulsen,et al.  Initial assessment of a simple system for frequency domain diffuse optical tomography. , 1995, Physics in medicine and biology.

[183]  N Ramanujam,et al.  Fluorescence spectroscopy: a diagnostic tool for cervical intraepithelial neoplasia (CIN). , 1994, Gynecologic oncology.

[184]  E. Sevick-Muraca,et al.  Quantitative optical spectroscopy for tissue diagnosis. , 1996, Annual review of physical chemistry.

[185]  E J BALDES,et al.  The photodynamic properties of a particular hematoporphyrin derivative. , 1960, Archives of dermatology.

[186]  Thomas Dreyer,et al.  Breast cancer: in vitro measurements of native fluorescence , 1996, European Conference on Biomedical Optics.

[187]  H. Bergh,et al.  In Vivo Fluence Rate Effect in Photodynamic Therapy of Early Cancers with Tetra(m‐hydroxyphenyl)chlorin , 1996, Photochemistry and photobiology.

[188]  Yang Yuanlong,et al.  Characteristic autofluorescence for cancer diagnosis and its origin , 1987, Lasers in surgery and medicine.

[189]  J Wu,et al.  Time-resolved multichannel imaging of fluorescent objects embedded in turbid media. , 1995, Optics letters.

[190]  B. C. Wilson,et al.  The sensitivity of normal brain and intracranially implanted VX2 tumour to interstitial photodynamic therapy. , 1996, British Journal of Cancer.

[191]  Harvey Lui,et al.  Monitoring of benzoporphyrin derivative monoacid ring A (BPD-MA) in skin tumors by fluorescence during photodynamic therapy: preliminary observations , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[192]  S. Svanberg,et al.  Medical diagnostic system based on simultaneous multispectral fluorescence imaging. , 1994, Applied optics.

[193]  E. Reddi.  Role of delivery vehicles for photosensitizers in the photodynamic therapy of tumours. , 1997, Journal of photochemistry and photobiology. B, Biology.

[194]  J. Mattiello,et al.  Hematoporphyrin‐derivative optical‐fluorescence‐detection instrument for localization of bladder and bronchous carcinoma in situ , 1986 .

[195]  Louis Guillou,et al.  Usefulness of fluorescence photodetection of neoplastic urothelial foci in bladder cancer following intravesical instillation of delta-aminolevulinic acid (5-ALA) , 1996, Photonics West.

[196]  G. Zonios,et al.  Morphological model of human colon tissue fluorescence , 1996, IEEE Transactions on Biomedical Engineering.

[197]  K Svanberg,et al.  Detection of adenocarcinoma in Barrett's oesophagus by means of laser induced fluorescence. , 1996, Gut.

[198]  Sharon Thomsen,et al.  Spectroscopic diagnosis of cervical intraepithelial neoplasia (CIN) in vivo using laser‐induced fluorescence spectra at multiple excitation wavlengths , 1996, Lasers in surgery and medicine.

[199]  H. Sterenborg,et al.  Quantification of the hematoporphyrin derivative by fluorescence measurementusing dual-wavelength excitation anddual-wavelength detection. , 1993, Applied optics.

[200]  R. Jindra,et al.  Hypericin in phototherapy. , 1996, Journal of photochemistry and photobiology. B, Biology.

[201]  H Stepp,et al.  Inhalation of 5-aminolevulinic acid: a new technique for fluorescence detection of early stage lung cancer. , 1996, Journal of photochemistry and photobiology. B, Biology.

[202]  A E Profio,et al.  Fluorescence of HpD for tumor detection and dosimetry in photoradiation therapy. , 1984, Progress in clinical and biological research.

[203]  H. Messmann,et al.  Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster. , 1996, British Journal of Cancer.

[204]  A. Profio,et al.  Fluorescence bronchoscopy in the localization of bronchogenic carcinoma , 1982, Cancer.

[205]  J. Marescaux,et al.  Photodynamic Imaging of a Rat Pancreatic Cancer with Pheophorbide a , 1996, Photochemistry and photobiology.

[206]  P van Hoogevest,et al.  Pharmacokinetics and body distribution of liposomal zinc phthalocyanine in tumor-bearing mice: influence of aggregation state, particle size, and composition. , 1995, Journal of pharmaceutical sciences.

[207]  J. Krasiński,et al.  The two-photon laser-induced fluorescence of the tumor-localizing photosensitizer hematoporphyrin derivative. Resonance-enhanced 750 nm two-photon excitation into the near-UV Soret band. , 1986, The Journal of biological chemistry.

[208]  Uwe Sukowski,et al.  Delayed observation of laser-induced fluorescence for imaging of tumors , 1993 .

[209]  J. Lakowicz,et al.  Fluorescence detection of the anticancer drug topotecan in plasma and whole blood by two-photon excitation. , 1996, Analytical biochemistry.

[210]  T. Papazoglou,et al.  Malignancies and atherosclerotic plaque diagnosis--is laser induced fluorescence spectroscopy the ultimate solution? , 1995, Journal of photochemistry and photobiology. B, Biology.

[211]  E J BALDES,et al.  Hematoporphyrin derivative: a new aid for endoscopic detection of malignant disease. , 1961, The Journal of thoracic and cardiovascular surgery.

[212]  K J Brodbeck,et al.  A system for real time fluorescence imaging in color for tumor diagnosis. , 1987, Medical physics.

[213]  B Palcic,et al.  Detection of squamous neoplasia by fluorescence imaging comparing porfimer sodium fluorescence to tissue autofluorescence in the hamster cheek-pouch model. , 1995, American journal of surgery.

[214]  D. Kessel,et al.  Localization and Efficacy Analysis of the Phototherapeutic Lutetium Texaphyrin (PCI‐0123) in the Murine EMT6 Sarcoma Model , 1997, Photochemistry and photobiology.

[215]  C. L. Hutchinson,et al.  Fluorescence lifetime-based sensing in tissues: a computational study. , 1995, Biophysical journal.

[216]  B. Tromberg,et al.  Photosensitization of the rat endometrium following 5‐aminolevulinic acid induced photodynamic therapy , 1996, Lasers in surgery and medicine.

[217]  Y. Garini,et al.  Fourier Transform Multipixel Spectroscopy and Spectral Imaging of Protoporphyrin in Single Melanoma Cells , 1996, Photochemistry and photobiology.

[218]  B. Palcic,et al.  Autofluorescence of normal and malignant bronchial tissue , 1991, Lasers in surgery and medicine.

[219]  E. Applebaum,et al.  Porphyrin fluorescence and photosensitization in head and neck cancer. , 1986, Archives of otolaryngology--head & neck surgery.

[220]  H. Bergh,et al.  Photodynamic Therapy for Choroidal Neovascularisation in Age-Related Macular Degeneration , 1998 .

[221]  J. E. Hansen,et al.  Validity of ear oximetry in clinical exercise testing. , 1987, Chest.

[222]  R. Martuza,et al.  Laser-induced fluorescence: experimental intraoperative delineation of tumor resection margins. , 1992, Journal of neurosurgery.

[223]  R Cubeddu,et al.  Fluorescence Lifetime Imaging of Experimental Tumors in Hematoporphyrin Derivative‐Sensitized Mice , 1997, Photochemistry and photobiology.

[224]  S. Minkin,et al.  Diet, aberrant crypt foci and colorectal cancer. , 1993, Mutation research.

[225]  F. R.DeGruijl,et al.  DOSE‐TIME DEPENDENCY OF TUMOR FORMATION BY CHRONIC UV EXPOSURE , 1983 .

[226]  C. L. Hutchinson,et al.  Fluorescence-lifetime determination in tissues or other scattering media from measurement of excitation and emission kinetics. , 1996, Applied optics.

[227]  Robert A. Glasgold,et al.  Tissue autofluorescence as an intermediate endpoint in NMBA-induced esophageal carcinogenesis. , 1994, Cancer letters.

[228]  R. Richards-Kortum,et al.  Study of the fluorescence properties of normal and neoplastic human cervical tissue , 1993, Lasers in surgery and medicine.

[229]  R Brancato,et al.  Iris fluorescein angiography in clinical practice. , 1997, Survey of ophthalmology.

[230]  Brian W. Pogue,et al.  Mathematical model for time-resolved and frequency-domain fluorescence spectroscopy in biological tissues. , 1994, Applied optics.

[231]  P. Pairolero,et al.  Roentgenographically occult lung cancer: pathologic findings and frequency of multicentricity during a 10-year period. , 1984, Mayo Clinic proceedings.

[232]  D L Farkas,et al.  Tumor Detection and Visualization Using Cyanine Fluorochrome‐Labeled Antibodies , 1997, Biotechnology progress.

[233]  T J Flotte,et al.  Ultraviolet laser-induced fluorescence of colonic polyps. , 1992, Gastroenterology.

[234]  S Mordon,et al.  Characterization of tumorous and normal tissue using a pH-sensitive fluorescence indicator (5,6-carboxyfluorescein) in vivo. , 1992, Journal of photochemistry and photobiology. B, Biology.

[235]  Patrice Jichlinski,et al.  Fluorescence excitation and emission spectra of ALA-induced protoporphyrin IX in normal and tumoral tissue of the human bladder , 1995, Other Conferences.

[236]  M. V. van Gemert,et al.  Fluorescence localization in tumour and normal brain after intratumoral injection of haematoporphyrin derivative into rat brain tumour. , 1995, Journal of photochemistry and photobiology. B, Biology.

[237]  J. M. Nauta,et al.  In vivo photo-detection of chemically induced premalignant lesions and squamous cell carcinoma of the rat palatal mucosa. , 1997, Journal of photochemistry and photobiology. B, Biology.

[238]  Z. Diwu.  NOVEL THERAPEUTIC AND DIAGNOSTIC APPLICATIONS OF HYPOCRELLINS AND HYPERICINS , 1995, Photochemistry and photobiology.

[239]  J Moan,et al.  Uptake of the components of hematoporphyrin derivative by cells and tumours. , 1983, Cancer letters.

[240]  J. Kennedy,et al.  Detection of Early Stages of Carcinogenesis in Adenomas of Murine Lung by 5‐Aminolevulinic Acid‐Induced Protoporphyrin IX Fluorescence , 1996, Photochemistry and photobiology.

[241]  A. J. MacRobert,et al.  Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy. , 1993, British Journal of Cancer.

[242]  C. Vernold,et al.  Tucson Organizations Bring Optics into Schools , 1996 .

[243]  B. Wilson,et al.  Light propagation in animal tissues in the wavelength range 375-825 nanometers. , 1984, Progress in clinical and biological research.

[244]  Bartow Sa,et al.  DNA flow cytometry in solid tumors: practical aspects and clinical applications. , 1989 .

[245]  M. Kitagawa,et al.  The frequency of a concomitant early esophageal cancer in male patients with oral and oropharyngeal cancer. Screening results using lugol dye endoscopy , 1994, Cancer.

[246]  Haishan Zeng,et al.  System for fast measurement of in-vivo tissue fluorescence spectra under multiple wavelength excitations , 1996, Photonics West.

[247]  H. Tajiri,et al.  Fluorescent diagnosis of experimental gastric cancer using a tumor-localizing photosensitizer. , 1997, Cancer letters.

[248]  Y. Furuya,et al.  Fluorescence photography as a diagnostic method for oral cancer. , 1996, Cancer letters.

[249]  G. Wagnières,et al.  Clinical pharmacokinetic studies of photofrin by fluorescence spectroscopy in the oral cavity, the esophagus, and the bronchi , 1995, Cancer.

[250]  T. Moore,et al.  Carotenoporphyrins as selective photodiagnostic agents for tumours. , 1994, British Journal of Cancer.

[251]  Stanley B. Brown,et al.  Fluorescence Photobleaching of ALA‐induced Protoporphyrin IX during Photodynamic Therapy of Normal Hairless Mouse Skin: The Effect of Light Dose and Irradiance and the Resulting Biological Effect , 1998, Photochemistry and photobiology.

[252]  Patrice Jichlinski,et al.  Tissue characterization by time-resolved fluorescence spectroscopy of endogenous and exogenous fluorochromes: apparatus design and preliminary results , 1996, European Conference on Biomedical Optics.

[253]  T M Jovin,et al.  Time resolved imaging microscopy. Phosphorescence and delayed fluorescence imaging. , 1991, Biophysical journal.

[254]  S L Jacques,et al.  Fluorescence spectroscopy of tissue: recovery of intrinsic fluorescence from measured fluorescence. , 1996, Applied optics.

[255]  K Svanberg,et al.  Clinical fluorescence diagnosis of human bladder carcinoma following low-dose Photofrin injection. , 1993, Urology.

[256]  D. Choy,et al.  Fluorescence spectra from cancerous and normal human breast and lung tissues , 1987, Annual Meeting Optical Society of America.

[257]  Study on the absorption properties of sulphonated aluminum phthalocyanine in vivo and ex vivo in murine tumor models. , 1997, Journal of biomedical optics.

[258]  A. Cincotta,et al.  Novel photodynamic effects of a benzophenothiazine on two different murine sarcomas. , 1994, Cancer research.

[259]  R. Alfano,et al.  Optical spectroscopic diagnosis of cancer and normal breast tissues , 1989 .

[260]  D. Jocham,et al.  A FLUORESCENCE IMAGING DEVICE FOR ENDOSCOPIC DETECTION OF EARLY STAGE CANCER – INSTRUMENTAL and EXPERIMENTAL STUDIES , 1987, Photochemistry and photobiology.

[261]  N. Brasseur,et al.  Photodynamic activities and biodistribution of fluorinated zinc phthalocyanine derivatives in the murine EMT‐6 tumour model , 1997, International journal of cancer.

[262]  Michael R Hamblin,et al.  Photosensitizer targeting in photodynamic therapy. I. Conjugates of haematoporphyrin with albumin and transferrin. , 1994, Journal of photochemistry and photobiology. B, Biology.

[263]  A. Katz,et al.  Innate cellular fluorescence reflects alterations in cellular proliferation , 1997, Lasers in surgery and medicine.

[264]  Georges Wagnières,et al.  AN ENDOSCOPIC FLUORESCENCE IMAGING SYSTEM FOR SIMULTANEOUS VISUAL EXAMINATION AND PHOTODETECTION OF CANCERS , 1997 .

[265]  U. Schmidt-Erfurth,et al.  Photodynamic targeting of human retinoblastoma cells using covalent low-density lipoprotein conjugates. , 1997, British Journal of Cancer.

[266]  Michael R Hamblin,et al.  Photosensitizer targeting in photodynamic therapy. II. Conjugates of haematoporphyrin with serum lipoproteins. , 1994, Journal of photochemistry and photobiology. B, Biology.

[267]  O. Balchum,et al.  Fluorescence bronchoscopy for localization of carcinoma in situ. , 1983, Medical physics.

[268]  L. Guillou,et al.  ©1999 Cancer Research Campaign Article no. bjoc.1998.0338 , 2022 .

[269]  R Baumgartner,et al.  Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid. , 1994, Urology.

[270]  G. Colice,et al.  Detecting lung cancer as a cause of hemoptysis in patients with a normal chest radiograph: bronchoscopy vs CT. , 1997, Chest.

[271]  L Lilgel,et al.  The sensitivity of normal brain and intracranially implanted VX2 tumour to interstitial photodynamic therapy , 1996, British Journal of Cancer.

[272]  C. Heusser,et al.  Immunophotodiagnosis of colon carcinomas in patients injected with fluoresceinated chimeric antibodies against carcinoembryonic antigen. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[273]  E. Gragoudas,et al.  Digital angiography of experimental choroidal melanomas using benzoporphyrin derivative. , 1997, American journal of ophthalmology.

[274]  Robert M. Clegg,et al.  Rapid acquisition, analysis, and display of fluorescence lifetime-resolved images for real-time applications , 1997 .

[275]  A E Profio,et al.  FLUORESCENCE SPECTRA IN LUNG WITH PORPHYRIN INJECTION , 1989, Photochemistry and photobiology.

[276]  H Stepp,et al.  Fluorescence cystoscopy following intravesical instillation of 5-aminolevulinic acid: a new procedure with high sensitivity for detection of hardly visible urothelial neoplasias. , 1995, Urologia internationalis.

[277]  Tuan Vo-Dinh,et al.  Laser-Induced Differential Fluorescence for Cancer Diagnosis without Biopsy , 1997 .

[278]  N Ramanujam,et al.  Development of a multivariate statistical algorithm to analyze human cervical tissue fluorescence spectra acquired in vivo , 1996, Lasers in surgery and medicine.

[279]  I Itzkan,et al.  Autofluorescence characteristics of oral mucosa , 1997, Head & neck.

[280]  R R Alfano,et al.  Pulsed and cw laser fluorescence spectra from cancerous, normal, and chemically treated normal human breast and lung tissues. , 1989, Applied optics.

[281]  A E Profio,et al.  Fluorometer for endoscopic diagnosis of tumors. , 1984, Medical physics.

[282]  R. Boyle,et al.  Structure and Biodistribution Relationships of Photodynamic Sensitizers * , 1996, Photochemistry and photobiology.

[283]  A. Batlle,et al.  Porphyrins, porphyrias, cancer and photodynamic therapy--a model for carcinogenesis. , 1993, Journal of photochemistry and photobiology. B, Biology.

[284]  T. Hasan,et al.  Biodistribution and phototoxicity of 5-aminolevulinic acid-induced PpIX in an orthotopic rat bladder tumor model. , 1995, The Journal of urology.

[285]  W. Star,et al.  In vivo fluorescence kinetics and photodynamic therapy using 5-aminolaevulinic acid-induced porphyrin: increased damage after multiple irradiations. , 1994, British Journal of Cancer.

[286]  T. Mang,et al.  Evaluation of porfimer sodium fluorescence for measuring tissue transformation , 1993, Cancer.

[287]  J. Gariépy,et al.  Loligomers: design of de novo peptide-based intracellular vehicles. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[288]  E Unsöld,et al.  Spectral variations of laser-induced tissue emission during in vivo detection of malignancies in the female genital tract. , 1997, Journal of photochemistry and photobiology. B, Biology.

[289]  B. Pogue,et al.  Fluorophore quantitation in tissue-simulating media with confocal detection , 1996 .

[290]  R R Alfano,et al.  Effect of multiple light scattering and self-absorption on the fluorescence and excitation spectra of dyes in random media. , 1994, Applied optics.

[291]  Thomas S. Mang,et al.  Fiber optic fluorescence detection of low-level porphyrin concentrations in preclinical and clinical studies , 1990, Photonics West - Lasers and Applications in Science and Engineering.

[292]  T J Flotte,et al.  Ultraviolet laser‐induced fluorescence of colonic tissue: Basic biology and diagnostic potential , 1992, Lasers in surgery and medicine.

[293]  Z. Malik,et al.  Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins. , 1987, British Journal of Cancer.

[294]  N. Bressler,et al.  The use of fundus photographs and fluorescein angiograms in the identification and treatment of choroidal neovascularization in the Macular Photocoagulation Study. The Macular Photocoagulation Study Group. , 1989, Ophthalmology.

[295]  B F Overholt,et al.  Endoscopic fluorescence detection of high-grade dysplasia in Barrett's esophagus. , 1996, Gastroenterology.

[296]  H Stepp,et al.  Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence. , 1998, Neurosurgery.

[297]  Sergiy M. Dets,et al.  Laser-induced fluorescence detection of stomach cancer using hypericin , 1996, European Conference on Biomedical Optics.

[298]  R Cubeddu,et al.  Study of porphyrin fluorescence in tissue samples of tumour-bearing mice. , 1995, Journal of photochemistry and photobiology. B, Biology.

[299]  N Ikeda,et al.  Photodynamic diagnosis in respiratory tract malignancy using an excimer dye laser system. , 1990, Journal of photochemistry and photobiology. B, Biology.

[300]  W. Star,et al.  In vivo FLUORESCENCE KINETICS OF PHTHALOCYANINES IN A SKIN‐FOLD OBSERVATION CHAMBER MODEL: ROLE OF CENTRAL METAL ION AND DEGREE OF SULFONATION , 1993, Photochemistry and photobiology.

[301]  T J Dougherty,et al.  Photoradiation in the treatment of recurrent breast carcinoma. , 1979, Journal of the National Cancer Institute.

[302]  T. Hasan,et al.  Role of neovasculature and vascular permeability on the tumor retention of photodynamic agents. , 1992, Cancer research.

[303]  William R. Potter,et al.  Fiberoptic Fluorescence Detection Of Low Level Porphyrin Concentrations In Occult Metastases Of Lymph Nodes , 1989, Photonics West - Lasers and Applications in Science and Engineering.

[304]  L. Dressler,et al.  DNA flow cytometry in solid tumors: practical aspects and clinical applications. , 1989, Seminars in diagnostic pathology.

[305]  F. Figge,et al.  Fluorescence of human lymphatic and cancer tissues following high doses of intravenous hematoporphyrin , 1955, Surgical forum.

[306]  H. C. Robertson,et al.  Hematoporphyrin‐Derivative Fluorescence in Malignant Neoplasms , 1968, Journal of the South Carolina Medical Association.

[307]  J. Duker,et al.  The digital indocyanine green videoangiography characteristics of well-defined choroidal neovascularization. , 1995, Ophthalmology.

[308]  H. Sterenborg,et al.  Mathematical description of photobleaching in vivo describing the influence of tissue optics on measured fluorescence signals. , 1997, Physics in medicine and biology.

[309]  L. Lilge,et al.  Laser induced fluorescence endoscopy (life) during photodynamic therapy (PDT) for esophageal cancer , 1997 .

[310]  Tayyaba Hasan,et al.  Quantitative fluorescence measurements from tissue using confocal detection , 1997, Photonics West - Biomedical Optics.

[311]  Massoud Motamedi,et al.  Spectroscopic detection of oral and skin tissue transformation in a model for squamous cell carcinoma: autofluorescence versus systemic aminolevulinic acid-induced fluorescence , 1996 .

[312]  K Svanberg,et al.  In vivo fluorescence imaging for tissue diagnostics. , 1997, Physics in medicine and biology.

[313]  D. Harris,et al.  Endogenous porphyrin fluorescence in tumors , 1987, Lasers in surgery and medicine.

[314]  H. S. de Bruijn,et al.  Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice. , 1996, British Journal of Cancer.

[315]  I Itzkan,et al.  Early diagnosis of upper aerodigestive tract cancer by autofluorescence. , 1996, Archives of otolaryngology--head & neck surgery.

[316]  F. Sieber,et al.  The alkyl-lysophospholipid, ET-18-OCH3 synergistically enhances the Merocyanine 540-mediated photoinactivation of leukemia cells: implications for the extracorporeal purging of autologous hematopoietic stem cells , 1997, Bone Marrow Transplantation.

[317]  Localization and treatment of transformed tissues using the photodynamic sensitizer 2‐[1‐hexyloxyethyl]‐2‐devinyl pyropheophorbide‐a , 1996, Lasers in surgery and medicine.

[318]  Hubert van den Bergh,et al.  Endoscopic tissue autofluorescence measurements in the upper aerodigestive tract and the bronchi , 1991, MedTech.

[319]  W. Star,et al.  Light dosimetry in vivo. , 1997, Physics in medicine and biology.

[320]  J. Rousseau,et al.  Photodynamic therapy of tumours with hexadecafluoro zinc phthalocyanine formulated in PEG‐coated poly(lactic acid) nanoparticles , 1996, International journal of cancer.

[321]  S. Svanberg,et al.  Fluorescence endoscopy instrumentation for improved tissue characterization. , 1987, Medical physics.

[322]  H. Reinhold,et al.  Tumour microcirculation as a target for hyperthermia. , 1986, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[323]  D. Bjorkman,et al.  Computer-assisted fluorescence identification of colon cancer in rats. , 1993, The American journal of gastroenterology.

[324]  G. Wagnières,et al.  Measurements by fluorescence microscopy of the time-dependent distribution of meso-tetra-hydroxyphenylchlorin in healthy tissues and chemically induced "early" squamous cell carcinoma of the Syrian hamster cheek pouch. , 1996, Journal of photochemistry and photobiology. B, Biology.

[325]  Gregg Staerkel,et al.  Cervical Precancer Detection Using a Multivariate Statistical Algorithm Based on Laser‐Induced Fluorescence Spectra at Multiple Excitation Wavelengths , 1996, Photochemistry and photobiology.

[326]  J. Rapkin,et al.  Digital fundus imaging of subretinal neovascularization. , 1992, Annals of ophthalmology.

[327]  J. J. Schuitmaker,et al.  Fluorescence and photodynamic effects of bacteriochlorin a observed in vivo in 'sandwich' observation chambers. , 1993, British Journal of Cancer.

[328]  David G. Whitten,et al.  PHOTOOXIDATION AND SINGLET OXYGEN SENSITIZATION BY PROTOPORPHYRIN IX AND ITS PHOTOOXIDATION PRODUCTS , 1982 .

[329]  R Cubeddu,et al.  TIME‐GATED FLUORESCENCE IMAGING FOR THE DIAGNOSIS OF TUMORS IN A MURINE MODEL , 1993, Photochemistry and photobiology.

[330]  B Palcic,et al.  Diagnostic imaging of the larynx: autofluorescence of laryngeal tumours using the helium-cadmium laser , 1995, The Journal of Laryngology & Otology.

[331]  S. Avrillier,et al.  Influence of the emission-reception geometry in laser-induced fluorescence spectra from turbid media. , 1998, Applied optics.

[332]  N Ramanujam,et al.  In vivo fluorescence spectroscopy: potential for non-invasive, automated diagnosis of cervical intraepithelial neoplasia and use as a surrogate endpoint biomarker. , 1994, Journal of cellular biochemistry. Supplement.

[333]  Alexander A. Stratonnikov,et al.  Spectral fluorescent properties of tissues in vivo with excitation in the red wavelength range , 1997, European Conference on Biomedical Optics.

[334]  A E Profio,et al.  Detection of dysplasia and carcinoma in situ with a lung imaging fluorescence endoscope device. , 1993, The Journal of thoracic and cardiovascular surgery.

[335]  Rick E. Sneed,et al.  In vivo cancer diagnosis of the esophagus using differential normalized fluorescence (DNF) indices , 1995, Lasers in surgery and medicine.

[336]  T. Hasan,et al.  Localization of lipoprotein-delivered benzoporphyrin derivative in the rabbit eye. , 1997, Current eye research.

[337]  Kristian Berg,et al.  Photobleaching of protoporphyrin IX in cells incubated with 5‐aminolevulinic acid , 1997, International journal of cancer.

[338]  J Marescaux,et al.  In vivo Laser‐induced Fluorescence Imaging of a Rat Pancreatic Cancer with Pheophorbide‐a , 1997, Photochemistry and photobiology.

[339]  C. Puliafito,et al.  Phthalocyanine photodynamic therapy: New strategy for closure of choroidal neovascularization , 1994, Lasers in surgery and medicine.

[340]  O. Cussenot,et al.  Laser induced autofluorescence diagnosis of bladder tumors: dependence on the excitation wavelength. , 1996, The Journal of urology.

[341]  Georgi Graschew,et al.  Imaging of tumors by time-delayed laser-induced fluorescence , 1991, MedTech.

[342]  H. Kato,et al.  Fiberoptic bronchoscopic photoradiation in experimentally induced canine lung cancer , 1983, Cancer.

[343]  Sanford H Barsky,et al.  Breast-duct endoscopy to study stages of cancerous breast disease , 1996, The Lancet.

[344]  A. Spigelman,et al.  Photodynamic therapy for polyps in familial adenomatous polyposis--a pilot study. , 1995, European journal of cancer.

[345]  C. L. Hutchinson,et al.  Optical Tissue Biodiagnostics Using Fluorescence Lifetime , 1996 .

[346]  B. Miller,et al.  Photodynamic therapy of subretinal neovascularization in the monkey eye. , 1993, Archives of ophthalmology.

[347]  M. Jackowski,et al.  Ultraviolet laser‐induced fluorescence of human stomach tissues: Detection of cancer tissues by imaging techniques , 1997, Lasers in surgery and medicine.

[348]  A. Welch,et al.  A review of the optical properties of biological tissues , 1990 .

[349]  A. Goetz,et al.  Targeting of the tumor microcirculation by photodynamic therapy with a synthetic porphycene. , 1997, Journal of photochemistry and photobiology. B, Biology.

[350]  H. S. de Bruijn,et al.  Photobleaching during and re‐appearance after photodynamic therapy of topical ALA‐induced fluorescence in UVB‐treated mouse skin , 1997, International journal of cancer.

[351]  S. J. Thomas,et al.  Slaked lime and betel nut cancer in Papua New Guinea , 1992, The Lancet.

[352]  Rapkin Js,et al.  Digital fundus imaging of subretinal neovascularization. , 1992 .

[353]  R. Marchesini,et al.  Natural fluorescence of normal and neoplastic human colon: A comprehensive “ex vivo” study , 1995, Lasers in surgery and medicine.

[354]  B. Khoobehi,et al.  Photodynamic therapy for choriocapillaris using tin ethyl etiopurpurin (SnET2). , 1997, Ophthalmic surgery and lasers.

[355]  A. Elsner,et al.  Indocyanine green videoangiography for the imaging of choroidal neovascularization associated with macular degeneration. , 1994, International ophthalmology clinics.

[356]  Christian D. Depeursinge,et al.  Photodetection of early cancer by laser-induced fluorescence of a tumor-selective dye: apparatus design and realization , 1990, Photonics West - Lasers and Applications in Science and Engineering.

[357]  J. Mourant,et al.  Elastic scattering spectroscopy as a diagnostic tool for differentiating pathologies in the gastrointestinal tract: preliminary testing. , 1996, Journal of biomedical optics.

[358]  A. Bohorfoush.  Tissue Spectroscopy for Gastrointestinal Diseases , 1996, Endoscopy.

[359]  K. Schomacker,et al.  Laser induced autofluorescence diagnosis of bladder cancer. , 1996, The Journal of urology.

[360]  J. Pawley,et al.  Handbook of Biological Confocal Microscopy , 1990, Springer US.