Ethical issues in research on control of the HIV/AIDS epidemic: report from a workshop of the World Federation of Scientists, Erice, Sicily, Italy, 22–24 August 2003

In research on control of the HIV/AIDS epidemic there are many ethical issues to be considered. The problem of personal autonomy versus the interest of society to prevent the spread of the disease in various settings makes it difficult to follow the regulations of the Declaration of Helsinki in all respects. This is particularly clear in the evaluation of trials aimed at preventing mother‐to‐child transmission of HIV. The interest of the child does not always conform to the policy of avoiding stigmatization of the mother.

[1]  H. Coovadia,et al.  Morbidity in children born to women infected with human immunodeficiency virus in South Africa: does mode of feeding matter? , 2003, Acta paediatrica.

[2]  Kofi Annan,et al.  A Challenge to the World's Scientists , 2003, Science.

[3]  Richard Horton,et al.  Medical journals: evidence of bias against the diseases of poverty , 2003, The Lancet.

[4]  J. Guilbert The world health report 2002 - reducing risks, promoting healthy life. , 2003, Education for health.

[5]  P. Hunt The right to health: from the margins to the mainstream , 2002, The Lancet.

[6]  R. Hogg,et al.  Time to act: global apathy towards HIV/AIDS is a crime against humanity , 2002, The Lancet.

[7]  R. Zetterström,et al.  Prospects of vaccination as a means of preventing mother‐to‐child transmission of HIV‐I * , 2002, Acta paediatrica.

[8]  Human immunodeficiency virus type‐1: mother‐to‐child transmission , 2000 .

[9]  F. Barré-Sinoussi,et al.  Human immunodeficiency virus type-1: mother-to-child transmission. Meeting of World Federation of Scientists in Erice, Italy, August 2000. Joint report of AIDS/Infectious Diseases PMP and Mother and Child PMP. , 2000, Acta paediatrica.

[10]  J. Hutton Ethics of medical research in developing countries: the role of international codes of conduct , 2000, Statistical methods in medical research.

[11]  T. Brennan Proposed revisions to the Declaration of Helsinki--will they weaken the ethical principles underlying human research? , 1999, The New England journal of medicine.

[12]  G. Annas,et al.  Human rights and maternal-fetal HIV transmission prevention trials in Africa. , 1998, American journal of public health.

[13]  L. Gilson,et al.  Cost-effectiveness of improved treatment services for sexually transmitted diseases in preventing HIV-1 infection in Mwanza Region, Tanzania , 1997, The Lancet.

[14]  J A Jacquez,et al.  Mother-to-child transmission of HIV-1. , 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

[15]  H. Varmus,et al.  Ethical complexities of conducting research in developing countries. , 1997, The New England journal of medicine.

[16]  W. Fawzi,et al.  The double burden of HIV infection and tuberculosis in sub-Saharan Africa. , 1997, The New England journal of medicine.

[17]  P. Lurie,et al.  Unethical trials of interventions to reduce perinatal transmission of the human immunodeficiency virus in developing countries. , 1997, The New England journal of medicine.

[18]  J. Hutton Statistics is Essential for Professional Ethics , 1995 .

[19]  P. Perre Postnatal transmission of human immunodeficiency virus type 1: The breast-feeding dilemma☆ , 1995 .

[20]  P. Van de Perre Postnatal transmission of human immunodeficiency virus type 1: the breast-feeding dilemma. , 1995, American journal of obstetrics and gynecology.