Metabolomic analysis of Shiga toxin 2a-induced injury in conditionally immortalized glomerular endothelial cells

[1]  V. Frémeaux-Bacchi,et al.  Haemolytic uraemic syndrome , 2017, The Lancet.

[2]  H. Karch,et al.  Shiga Toxin 2a-Induced Endothelial Injury in Hemolytic Uremic Syndrome: A Metabolomic Analysis. , 2016, The Journal of infectious diseases.

[3]  T. Ng,et al.  Shiga toxins: from structure and mechanism to applications , 2015, Applied Microbiology and Biotechnology.

[4]  J. Debnath,et al.  Autophagy at the crossroads of catabolism and anabolism , 2015, Nature Reviews Molecular Cell Biology.

[5]  M. Zou,et al.  Tryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation. , 2015, Frontiers in bioscience.

[6]  J. Gu,et al.  Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway , 2015, Autophagy.

[7]  A. Engelman,et al.  Retroviral Integrase Structure and DNA Recombination Mechanism , 2014, Microbiology spectrum.

[8]  Angela R Melton-Celsa,et al.  Shiga Toxin (Stx) Classification, Structure, and Function , 2014, Microbiology spectrum.

[9]  M. Lila,et al.  Serum metabolic signatures induced by a three-day intensified exercise period persist after 14 h of recovery in runners. , 2013, Journal of proteome research.

[10]  G. Fernández,et al.  The oxidative stress induced in vivo by Shiga toxin‐2 contributes to the pathogenicity of haemolytic uraemic syndrome , 2013, Clinical and experimental immunology.

[11]  H. Karch,et al.  Expression of Shiga toxin 2e glycosphingolipid receptors of primary porcine brain endothelial cells and toxin-mediated breakdown of the blood-brain barrier. , 2013, Glycobiology.

[12]  V. L. Tesh,et al.  Activation of cell stress response pathways by Shiga toxins , 2012, Cellular microbiology.

[13]  D. Leyva-Illades,et al.  Shiga toxins induce autophagy leading to differential signalling pathways in toxin‐sensitive and toxin‐resistant human cells , 2011, Cellular microbiology.

[14]  C. Paz,et al.  Oxidative stress status during the acute phase of haemolytic uraemic syndrome. , 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[15]  Patrik Langehanenberg,et al.  Differential cytotoxic actions of Shiga toxin 1 and Shiga toxin 2 on microvascular and macrovascular endothelial cells , 2010, Thrombosis and Haemostasis.

[16]  Anne M. Evans,et al.  Organization of GC/MS and LC/MS metabolomics data into chemical libraries , 2010, J. Cheminformatics.

[17]  L. Johannes,et al.  Shiga toxins — from cell biology to biomedical applications , 2010, Nature Reviews Microbiology.

[18]  Corey D. DeHaven,et al.  Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems. , 2009, Analytical chemistry.

[19]  Yoshiaki Kamada,et al.  Dynamics and diversity in autophagy mechanisms: lessons from yeast , 2009, Nature Reviews Molecular Cell Biology.

[20]  M. Czaja,et al.  Autophagy regulates lipid metabolism , 2009, Nature.

[21]  J. Kopp,et al.  Conditionally immortalized human , 2009 .

[22]  A. Gvozdjáková Mitochondrial medicine : Mitochondrial metabolism, diseases, diagnosis and therapy , 2008 .

[23]  D. Klionsky,et al.  Protein turnover via autophagy: implications for metabolism. , 2007, Annual review of nutrition.

[24]  G. Remuzzi,et al.  Hemolytic uremic syndrome. , 2005, Journal of the American Society of Nephrology : JASN.

[25]  L. V. D. Heuvel,et al.  Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF. , 2006, Kidney international.

[26]  Masaaki Komatsu,et al.  Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice , 2005, The Journal of cell biology.

[27]  C. Lingwood,et al.  Induction by Sphingomyelinase of Shiga Toxin Receptor and Shiga Toxin 2 Sensitivity in Human Microvascular Endothelial Cells , 2003, Infection and Immunity.

[28]  D. Kohan,et al.  Induction of apoptosis of human brain microvascular endothelial cells by shiga toxin 1. , 2003, The Journal of infectious diseases.

[29]  D. Kohan,et al.  Effect of shigatoxin-1 on arachidonic acid release by human glomerular epithelial cells. , 2001, Kidney international.

[30]  P. Stricklett,et al.  Cytotoxic effect of Shiga toxin-1 on human glomerular epithelial cells. , 2000, Kidney international.

[31]  C. Lingwood,et al.  Endothelial heterogeneity in Shiga toxin receptors and responses. , 1993, The Journal of biological chemistry.

[32]  P. Berk,et al.  Mechanisms of cellular uptake of free fatty acids. , 1989, Annual review of nutrition.