Laser Polarinetry For Measurement Of Drugs In The Aqueous Humor

We used laser polarimetry for measuring glucose concentrations in buffd saline. The ratio of output voltages were heady related over the 25-250 mg/dl range when plotted by a least squares fit When L-alanine (15 mg/dl), an optically active amino acid. was added to the glucose solutions over the same 25-250 mg/dl range, it caused a near castant shift in optical rotation of linearly polarized light when compared to glucose alone. We determined the optical rotation of a sample by measuring changes in the system output voltage. To calibrate the voltage output voltage, we determined the ratios of a reference signal to different test signals. The lam were measured by using reference samples of glucose over the test range.

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