Microassembly of complex and three-dimensional microstructures using holographic optical tweezers

In this paper we investigate a flexible method for the fabrication of complex microstructures using binding microparticles. Utilizing optical forces, micro-objects are caught, positioned and used as building blocks to form defined structures, analogous to assembling processes in the macroscopic world. Durable linkage between the individual particles is realized using biomolecules with high affinities applied as particle coatings. Planar structures can be assembled employing optical manipulation as well as three-dimensional patterns by stacking the generated layers. Even the properties of the generated structures can be locally designed as desired by using building blocks from diverse materials exhibiting different properties. This method benefits from its simplicity and the potential extensibility of the fabricated structure at any time of the experiment.

[1]  P. Tavan,et al.  Ligand Binding: Molecular Mechanics Calculation of the Streptavidin-Biotin Rupture Force , 1996, Science.

[2]  Hiroshi Masuhara,et al.  Laser manipulation and assembling of polymer latex particles in solution , 1993 .

[3]  A. Ashkin.  Forces of a single-beam gradient laser trap on a dielectric sphere in the ray optics regime. , 1992, Methods in cell biology.

[4]  B N Chichkov,et al.  Femtosecond laser-induced two-photon polymerization of inorganic-organic hybrid materials for applications in photonics. , 2003, Optics letters.

[5]  Yael Roichman,et al.  Holographic optical trapping. , 2006, Applied optics.

[6]  Properties of Three-Dimensional Precision Objects Fabricated by Using Laser Based Micro Stereo Lithography , 2008 .

[7]  D. Hutmacher,et al.  Scaffolds in tissue engineering bone and cartilage. , 2000, Biomaterials.

[8]  Joakim Lundeberg,et al.  The biotin‐streptavidin interaction can be reversibly broken using water at elevated temperatures , 2005, Electrophoresis.

[9]  Peter Fischer,et al.  The self-assembly, aggregation and phase transitions of food protein systems in one, two and three dimensions , 2013, Reports on progress in physics. Physical Society.

[10]  Jennifer E. Curtis,et al.  Dynamic holographic optical tweezers , 2002 .

[11]  Y. Waseda,et al.  Optical trapping of microscopic metal particles. , 1994, Optics letters.

[12]  Satoshi Kawata,et al.  Rupture force measurement of biotin-streptavidin bonds using optical trapping , 2005 .

[13]  Shoji Maruo,et al.  Optically driven micropump produced by three-dimensional two-photon microfabrication , 2006 .

[14]  H. Tiziani,et al.  Multi-functional optical tweezers using computer-generated holograms , 2000 .

[15]  David W. M. Marr,et al.  Fabrication of linear colloidal structures for microfluidic applications , 2002 .

[16]  In-Yong Park,et al.  Manufacturing micro-scale structures by an optical tweezers system controlled by five finger tips , 2007 .

[17]  R. Gerchberg.  A practical algorithm for the determination of phase from image and diffraction plane pictures , 1972 .

[18]  Johannes Courtial,et al.  Interactive approach to optical tweezers control. , 2006, Applied optics.

[19]  Norman R. Heckenberg,et al.  Optical Particle Trapping with Higher-order Doughnut Beams Produced Using High Efficiency Computer Generated Holograms , 1995 .

[20]  D. Burnham,et al.  Holographic optical trapping of aerosol droplets. , 2006, Optics express.

[21]  A. Ashkin,et al.  Optical trapping and manipulation of neutral particles using lasers. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[22]  Metin Sitti,et al.  Manufacturing of two and three-dimensional micro/nanostructures by integrating optical tweezers with chemical assembly , 2005, Robotica.

[23]  G. Whitesides.  The origins and the future of microfluidics , 2006, Nature.

[24]  Hiroshi Masuhara,et al.  Photothermal fixation of laser-trapped polymer microparticles on polymer substrates , 1999 .

[25]  Giancarlo Ruocco,et al.  Computer generation of optimal holograms for optical trap arrays. , 2007, Optics express.

[26]  H. Gaub,et al.  Intermolecular forces and energies between ligands and receptors. , 1994, Science.

[27]  Mario Surbek,et al.  Optically based Manufacturing with Polymer Particles , 2010 .

[28]  Martin Meister,et al.  Novel approaches to direct search algorithms for the design of diffractive optical elements , 2002 .