Translating Innate Immunity into Immunological Memory: Implications for Vaccine Development

[1]  B. Pulendran,et al.  Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. , 2006, The Journal of clinical investigation.

[2]  S. Akira,et al.  Pathogen Recognition and Innate Immunity , 2006, Cell.

[3]  Bali Pulendran,et al.  Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity , 2006, The Journal of experimental medicine.

[4]  G. Freeman,et al.  Restoring function in exhausted CD8 T cells during chronic viral infection , 2006, Nature.

[5]  H. S. Warren,et al.  Toll-like receptors. , 2005, Critical care medicine.

[6]  S. Wessely,et al.  Analysis of Anthrax and Plague Biowarfare Vaccine Interactions with Human Monocyte-Derived Dendritic Cells1 , 2005, The Journal of Immunology.

[7]  R. Koup,et al.  HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[8]  F. Guirakhoo,et al.  New developments in flavivirus vaccines with special attention to yellow fever , 2005, Current opinion in infectious diseases.

[9]  J. Sprent,et al.  Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection , 2005, The Journal of experimental medicine.

[10]  Weiyi Peng,et al.  Toll-Like Receptor 8-Mediated Reversal of CD4+ Regulatory T Cell Function , 2005, Science.

[11]  E. Butcher,et al.  Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues , 2005, Nature Immunology.

[12]  Francesco Bertoni,et al.  Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells , 2005, Nature Immunology.

[13]  Renate Kunert,et al.  Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies , 2005, Science.

[14]  M. Chamaillard,et al.  NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. , 2005, Annual review of biochemistry.

[15]  A. Aderem.  Systems Biology: Its Practice and Challenges , 2005, Cell.

[16]  R. Steinman,et al.  Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients , 2005, The Journal of experimental medicine.

[17]  S. Plotkin,et al.  Vaccines: past, present and future , 2005, Nature Medicine.

[18]  B. Pulendran.  Variegation of the Immune Response with Dendritic Cells and Pathogen Recognition Receptors1 , 2005, The Journal of Immunology.

[19]  E. Wherry,et al.  Bone Marrow Is a Preferred Site for Homeostatic Proliferation of Memory CD8 T Cells , 2005, The Journal of Immunology.

[20]  Yong‐jun Liu,et al.  IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. , 2005, Annual review of immunology.

[21]  L. McHeyzer-Williams,et al.  Antigen-specific memory B cell development. , 2005, Annual review of immunology.

[22]  G. Freeman,et al.  The B7 family revisited. , 2005, Annual review of immunology.

[23]  L. Herzenberg,et al.  Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion , 2005, Springer Seminars in Immunopathology.

[24]  R. Germain.  An innately interesting decade of research in immunology , 2004, Nature Medicine.

[25]  L. Glimcher,et al.  Signaling pathways in Th2 development , 2004, Immunological reviews.

[26]  Lei Shen,et al.  Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity , 2004, Nature Biotechnology.

[27]  R. Rappuoli.  From Pasteur to genomics: progress and challenges in infectious diseases , 2004, Nature Medicine.

[28]  Si-young Song,et al.  Retinoic acid imprints gut-homing specificity on T cells. , 2004, Immunity.

[29]  R. Germain,et al.  Illuminating the landscape of in vivo immunity: insights from dynamic in situ imaging of secondary lymphoid tissues. , 2004, Immunity.

[30]  A. O’Garra,et al.  Regulatory T cells and mechanisms of immune system control , 2004, Nature Medicine.

[31]  B. Beutler,et al.  Inferences, questions and possibilities in Toll-like receptor signalling , 2004, Nature.

[32]  B. Pulendran.  Modulating vaccine responses with dendritic cells and Toll‐like receptors , 2004, Immunological reviews.

[33]  B. Pulendran,et al.  A Toll-Like Receptor 2 Ligand Stimulates Th2 Responses In Vivo, via Induction of Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and c-Fos in Dendritic Cells 1 , 2004, The Journal of Immunology.

[34]  R. Ward,et al.  Activated Primary and Memory CD8 T Cells Migrate to Nonlymphoid Tissues Regardless of Site of Activation or Tissue of Origin1 , 2004, The Journal of Immunology.

[35]  Antonio Lanzavecchia,et al.  Central memory and effector memory T cell subsets: function, generation, and maintenance. , 2004, Annual review of immunology.

[36]  T. Geijtenbeek,et al.  Self- and nonself-recognition by C-type lectins on dendritic cells. , 2004, Annual review of immunology.

[37]  E. Raz,et al.  Cutting Edge: Activation of Toll-Like Receptor 2 Induces a Th2 Immune Response and Promotes Experimental Asthma1 , 2004, The Journal of Immunology.

[38]  J. Kearney,et al.  Development and selection of marginal zone B cells , 2004, Immunological reviews.

[39]  S. Henrickson,et al.  T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases , 2004, Nature.

[40]  R. Jove,et al.  Hyperactivation of STAT3 Is Involved in Abnormal Differentiation of Dendritic Cells in Cancer , 2004, The Journal of Immunology.

[41]  P. Marrack,et al.  Control of T cell viability. , 2003, Annual review of immunology.

[42]  L. Thomsen,et al.  Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. , 2004, Nature immunology.

[43]  D. Robinson,et al.  Development and function of T helper 1 cells. , 2004, Advances in immunology.

[44]  E. Wherry,et al.  Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells , 2003, Nature Immunology.

[45]  P. Schneider,et al.  BAFF AND APRIL: a tutorial on B cell survival. , 2003, Annual review of immunology.

[46]  T. Mueller,et al.  Timing of IFN-β Exposure during Human Dendritic Cell Maturation and Naive Th Cell Stimulation Has Contrasting Effects on Th1 Subset Generation: A Role for IFN-β-Mediated Regulation of IL-12 Family Cytokines and IL-18 in Naive Th Cell Differentiation1 , 2003, The Journal of Immunology.

[47]  B. Pulendran,et al.  Cutting Edge: Different Toll-Like Receptor Agonists Instruct Dendritic Cells to Induce Distinct Th Responses via Differential Modulation of Extracellular Signal-Regulated Kinase-Mitogen-Activated Protein Kinase and c-Fos 1 , 2003, The Journal of Immunology.

[48]  Luis Villarreal,et al.  Cutting Edge: Long-Term B Cell Memory in Humans after Smallpox Vaccination 1 , 2003, The Journal of Immunology.

[49]  James E. Evans,et al.  Molecular identification of a danger signal that alerts the immune system to dying cells , 2003, Nature.

[50]  P. Borrow,et al.  Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon , 2003, Nature Immunology.

[51]  S. Hansen,et al.  Duration of antiviral immunity after smallpox vaccination , 2003, Nature Medicine.

[52]  Virginia Pascual,et al.  Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. , 2003, Immunity.

[53]  K. Toellner,et al.  Extrafollicular antibody responses , 2003, Immunological reviews.

[54]  Bali Pulendran,et al.  Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin , 2003, Nature.

[55]  A. Rudensky,et al.  Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. , 2003, Immunity.

[56]  Antonio Lanzavecchia,et al.  T cell fitness determined by signal strength , 2003, Nature Immunology.

[57]  I. Haga,et al.  The Poxvirus Protein A52R Targets Toll-like Receptor Signaling Complexes to Suppress Host Defense , 2003, The Journal of experimental medicine.

[58]  Ruslan Medzhitov,et al.  Toll Pathway-Dependent Blockade of CD4+CD25+ T Cell-Mediated Suppression by Dendritic Cells , 2003, Science.

[59]  Antonio Lanzavecchia,et al.  Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells , 2002, Science.

[60]  L. Kobzik,et al.  Functional Activity of Natural Antibody is Altered in Cr2-Deficient Mice1 , 2002, The Journal of Immunology.

[61]  W. Agace,et al.  CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa. , 2002, The Journal of clinical investigation.

[62]  A. Santoni,et al.  Bone marrow CD8 T cells are in a different activation state than those in lymphoid periphery , 2002, European journal of immunology.

[63]  Kathleen M. Smith,et al.  Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP , 2002, Nature Immunology.

[64]  Mark J. Miller,et al.  Two-Photon Imaging of Lymphocyte Motility and Antigen Response in Intact Lymph Node , 2002, Science.

[65]  Michael Loran Dustin,et al.  The immunological synapse , 2002, Arthritis research.

[66]  Rustom Antia,et al.  Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells , 2002, The Journal of experimental medicine.

[67]  Yong‐jun Liu,et al.  Mouse and human dendritic cell subtypes , 2002, Nature Reviews Immunology.

[68]  J. Yewdell,et al.  Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo , 2002, Nature Immunology.

[69]  C. Bogdan,et al.  Repetitive Injections of Dendritic Cells Matured with Tumor Necrosis Factor α Induce Antigen-specific Protection of Mice from Autoimmunity , 2002, The Journal of experimental medicine.

[70]  Susan M. Kaech,et al.  Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol. , 2002 .

[71]  P. Srivastava,et al.  Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. , 2002, Annual review of immunology.

[72]  C. Janeway,et al.  Innate immune recognition. , 2002, Annual review of immunology.

[73]  Michel C. Nussenzweig,et al.  Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo , 2001, The Journal of experimental medicine.

[74]  J. Lieberman,et al.  Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. , 2001, The Journal of clinical investigation.

[75]  Dirk Homann,et al.  Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory , 2001, Nature Medicine.

[76]  F. Sallusto,et al.  Antigen decoding by T lymphocytes: from synapses to fate determination , 2001, Nature Immunology.

[77]  Stephen P. Schoenberger,et al.  Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation , 2001, Nature Immunology.

[78]  Susan M. Kaech,et al.  Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells , 2001, Nature Immunology.

[79]  A. Iwasaki,et al.  Unique Functions of CD11b+, CD8α+, and Double-Negative Peyer’s Patch Dendritic Cells1 , 2001, The Journal of Immunology.

[80]  L. Lefrançois,et al.  Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue , 2001, Science.

[81]  A. Iwasaki,et al.  Unique functions of CD11b+, CD8 alpha+, and double-negative Peyer's patch dendritic cells. , 2001, Journal of immunology.

[82]  Eric G. Pamer,et al.  Early Programming of T Cell Populations Responding to Bacterial Infection1 , 2000, The Journal of Immunology.

[83]  K. Rajewsky,et al.  Memory B-cell persistence is independent of persisting immunizing antigen , 2000, Nature.

[84]  R. Ahmed,et al.  Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses. , 2000, Current opinion in immunology.

[85]  J. Altman,et al.  Cutting Edge: Increased Expression of Bcl-2 in Antigen-Specific Memory CD8+ T Cells1 , 2000, The Journal of Immunology.

[86]  R. Steinman,et al.  Trance, a Tumor Necrosis Factor Family Member, Enhances the Longevity and Adjuvant Properties of Dendritic Cells in Vivo , 2000, The Journal of experimental medicine.

[87]  C Caux,et al.  Immunobiology of dendritic cells. , 2000, Annual review of immunology.

[88]  G. Kelsoe.  Studies of the humoral immune response , 2000, Immunologic research.

[89]  D. Fearon,et al.  Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. , 2000, Annual review of immunology.

[90]  J. Altman,et al.  Persistence of memory CD8 T cells in MHC class I-deficient mice. , 1999, Science.

[91]  James J. Campbell,et al.  Human G Protein–Coupled Receptor Gpr-9-6/Cc Chemokine Receptor 9 Is Selectively Expressed on Intestinal Homing T Lymphocytes, Mucosal Lymphocytes, and Thymocytes and Is Required for Thymus-Expressed Chemokine–Mediated Chemotaxis , 1999, The Journal of experimental medicine.

[92]  B. Bloom,et al.  Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. , 1999, Science.

[93]  C. Elson,et al.  Differential homing commitments of antigen-specific T cells after oral or parenteral immunization in humans. , 1999, Journal of immunology.

[94]  J. Cyster,et al.  Chemokine Up-regulation and activated T cell attraction by maturing dendritic cells. , 1999, Science.

[95]  N. Kadowaki,et al.  Reciprocal control of T helper cell and dendritic cell differentiation. , 1999, Science.

[96]  B. Pulendran,et al.  Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[97]  R. Maldonado-López,et al.  CD8α+ and CD8α− Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo , 1999, The Journal of experimental medicine.

[98]  J. Altman,et al.  Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function , 1998, The Journal of experimental medicine.

[99]  R. Ahmed,et al.  Humoral immunity due to long-lived plasma cells. , 1998, Immunity.

[100]  J. Altman,et al.  Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. , 1998, Immunity.

[101]  M. Bevan,et al.  Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. , 1998, Immunity.

[102]  K. Rajewsky,et al.  In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death , 1997, Cell.

[103]  Andreas Radbruch,et al.  Lifetime of plasma cells in the bone marrow , 1997, Nature.

[104]  David Gray,et al.  Immunological Memory and Protective Immunity: Understanding Their Relation , 1996, Science.

[105]  Christopher C. Goodnow,et al.  C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity , 1996, Science.

[106]  E. Butcher,et al.  Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo. , 1994, Journal of immunology.

[107]  P. Matzinger.  Tolerance, danger, and the extended family. , 1994, Annual review of immunology.

[108]  R. Zinkernagel,et al.  Peripheral clonal deletion of antiviral memory CD8+ T cells , 1993, European journal of immunology.

[109]  AC Tose.  Cell , 1993, Cell.

[110]  D. Gray,et al.  B-cell memory is short-lived in the absence of antigen. , 1991, Nature.