Auditory two-tone suppression from a subcritical Hopf cochlea

Cochlear two-tone suppression is the dominant contrast-sharpening phenomenon of hearing and provides a decisive test for the correct implementation of hearing nonlinearities in models of the cochlea. Although critically tuned Hopf amplifiers were shown recently to be fruitful models of intricate phenomena in the physiology of the human ear, we find that only a model based on subcritical Hopf amplifiers is capable of reproducing physiologically measured two-tone suppression data adequately. In addition, we provide a detailed explanation of the two-tone suppression phenomenon, including its quantitative characterization.

[1]  M. Ruggero Responses to sound of the basilar membrane of the mammalian cochlea , 1992, Current Opinion in Neurobiology.

[2]  D. T. Kemp,et al.  Evidence of mechanical nonlinearity and frequency selective wave amplification in the cochlea , 2004, Archives of oto-rhino-laryngology.

[3]  E. D. Boer,et al.  Mechanics of the Cochlea: Modeling Efforts , 1996 .

[4]  C. D. Geisler,et al.  From Sound to Synapse: Physiology of the Mammalian Ear , 1998 .

[5]  Marcelo O Magnasco A wave traveling over a Hopf instability shapes the cochlear tuning curve. , 2003, Physical review letters.

[6]  W. S. Rhode,et al.  Basilar membrane mechanics in the hook region of cat and guinea-pig cochleae: Sharp tuning and nonlinearity in the absence of baseline position shifts , 1992, Hearing Research.

[7]  L. Chambers Linear and Nonlinear Waves , 2000, The Mathematical Gazette.

[8]  Mario A. Ruggero,et al.  Two-tone distortion in the basilar membrane of the cochlea , 1991, Nature.

[9]  Frank Jülicher,et al.  Active traveling wave in the cochlea. , 2003, Physical review letters.

[10]  Robert Patuzzi,et al.  Cochlear Micromechanics and Macromechanics , 1996 .

[11]  L. Robles,et al.  Two-tone suppression in the basilar membrane of the cochlea: mechanical basis of auditory-nerve rate suppression. , 1992, Journal of neurophysiology.

[12]  C. Daniel Geisler,et al.  A cochlear model using feed-forward outer-hair-cell forces , 1995, Hearing Research.

[13]  B. M. Johnstone,et al.  The modulation of the sensitivity of the mammalian cochlea by low frequency tones. III. Basilar membrane motion , 1984, Hearing Research.

[14]  A J Hudspeth,et al.  Compressive nonlinearity in the hair bundle's active response to mechanical stimulation , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[15]  P. Dallos,et al.  The Cochlea: Springer Handbook of Auditory Research , 1996 .

[16]  Anthony W. Gummer,et al.  Biophysics of the Cochlea From Molecules to Models , 2003 .

[17]  A. Hudspeth,et al.  Essential nonlinearities in hearing. , 2000, Physical review letters.

[18]  Peter Dallos,et al.  Chapter 4 – BIOPHYSICS OF THE COCHLEA* , 1978 .

[19]  R. Stoop,et al.  Essential Role of Couplings between Hearing Nonlinearities. , 2003, Physical review letters.