Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

[1]  James M. Roberts,et al.  Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. , 1996, Genes & development.

[2]  James M. Roberts,et al.  A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 Kip1 -Deficient Mice , 1996, Cell.

[3]  H. Koeffler,et al.  p27/Kip1 mutation found in breast cancer. , 1996, Cancer research.

[4]  James M. Roberts,et al.  Requirement of p27Kip1 for Restriction Point Control of the Fibroblast Cell Cycle , 1996, Science.

[5]  B. Clurman,et al.  Cell cycle and cancer. , 1995, Journal of the National Cancer Institute.

[6]  P. Beer-Romero,et al.  Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. , 1995, Science.

[7]  Anindya Dutta,et al.  Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[8]  James M. Roberts,et al.  Human cyclin E, a nuclear protein essential for the G1-to-S phase transition , 1995, Molecular and cellular biology.

[9]  D. Medina,et al.  Cell cyclins and cyclin-dependent kinase activities in mouse mammary tumor development. , 1995, Carcinogenesis.

[10]  J. Massagué,et al.  p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. , 1995, Cancer research.

[11]  James M. Roberts,et al.  Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. , 1995, Cancer research.

[12]  James M. Roberts,et al.  lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin , 1994, Nature.

[13]  E. Lees,et al.  Cyclin E, a potential prognostic marker for breast cancer. , 1994, Cancer research.

[14]  S. Elledge,et al.  Amplification of cyclin genes in colorectal carcinomas. , 1993, Cancer research.

[15]  James M. Roberts,et al.  Cyclin-dependent regulation of G1 in mammalian fibroblasts. , 1993, Science.

[16]  W. McGuire,et al.  Prognostic factors and therapeutic decisions in axillary node-negative breast cancer. , 1992, Annual review of medicine.

[17]  Z. Ying,et al.  Cox Regression with Incomplete Covariate Measurements , 1993 .

[18]  S. Reed,et al.  Association of human cyclin E with a periodic G1-S phase protein kinase. , 1992, Science.

[19]  J. Gerdes,et al.  Immunohistological detection of tumour growth fraction (Ki-67 antigen) in formalin-fixed and routinely processed tissues. , 1992, The Journal of pathology.

[20]  James M. Roberts,et al.  Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family , 1991, Cell.