Functionally graded additive manufacturing to achieve functionality specifications of osteochondral scaffolds

The authors would like to thank H2020-MSCARISE programme, as this work is part of developments carried out in BAMOS project, funded from the European Union’s Horizon 2020 research and innovation programme under Grant Agreement No. 734156.

[1]  Eujin Pei,et al.  A study of 4D printing and functionally graded additive manufacturing , 2017 .

[2]  Jerry C. Hu,et al.  Articular Cartilage Tissue Engineering , 2009 .

[3]  S. Clockaerts,et al.  TruFit Plug for Repair of Osteochondral Defects—Where Is the Evidence? Systematic Review of Literature , 2015, Cartilage.

[4]  J. Oliveira,et al.  Basic science of osteoarthritis , 2016, Journal of Experimental Orthopaedics.

[5]  S Zaffagnini,et al.  Osteochondral scaffold reconstruction for complex knee lesions: a comparative evaluation. , 2013, The Knee.

[6]  M. Lind,et al.  Poor osteochondral repair by a biomimetic collagen scaffold: 1- to 3-year clinical and radiological follow-up , 2016, Knee Surgery, Sports Traumatology, Arthroscopy.

[7]  K. Vincken,et al.  Articular Cartilage Evaluation After TruFit Plug Implantation Analyzed by Delayed Gadolinium-Enhanced MRI of Cartilage (dGEMRIC) , 2013, The American journal of sports medicine.

[8]  M. Monzón,et al.  Anisotropy of Photopolymer Parts Made by Digital Light Processing , 2017, Materials.

[9]  Luis Suárez,et al.  Lightweight parametric design optimization for 4D printed parts , 2017, Integr. Comput. Aided Eng..

[10]  M. Marcacci,et al.  Tibial plateau lesions. Surface reconstruction with a biomimetic osteochondral scaffold: Results at 2 years of follow-up. , 2014, Injury.

[11]  C K Chua,et al.  Investigation of the mechanical properties and porosity relationships in selective laser-sintered polyhedral for functionally graded scaffolds. , 2011, Acta biomaterialia.

[12]  Maurilio Marcacci,et al.  Treatment of Knee Osteochondritis Dissecans With a Cell-Free Biomimetic Osteochondral Scaffold , 2013, The American journal of sports medicine.

[13]  Tomiharu Matsushita,et al.  Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: An in vivo experiment. , 2016, Materials science & engineering. C, Materials for biological applications.

[14]  Yong Woo Cho,et al.  Piezoelectric inkjet printing of polymers: Stem cell patterning on polymer substrates , 2010 .

[15]  M. D. Monzón,et al.  Standardization in additive manufacturing: activities carried out by international organizations and projects , 2015 .

[16]  S. Matsuda,et al.  Title Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: An in vivo , 2017 .

[17]  Jaesung Park,et al.  Development of a hybrid scaffold with synthetic biomaterials and hydrogel using solid freeform fabrication technology , 2011, Biofabrication.

[18]  Marta Ondrésik,et al.  Management of knee osteoarthritis. Current status and future trends , 2017, Biotechnology and bioengineering.

[19]  S. Van Vlierberghe,et al.  Bioink properties before, during and after 3D bioprinting , 2016, Biofabrication.

[20]  Maurilio Marcacci,et al.  Novel Nano-composite Multilayered Biomaterial for Osteochondral Regeneration , 2011, The American journal of sports medicine.

[21]  Xuesi Chen,et al.  Biomimetic biphasic scaffolds for osteochondral defect repair , 2015, Regenerative biomaterials.

[22]  P. Verdonk,et al.  A novel aragonite-based scaffold for osteochondral regeneration: early experience on human implants and technical developments. , 2016, Injury.

[23]  David Dean,et al.  Stereolithographic bone scaffold design parameters: osteogenic differentiation and signal expression. , 2010, Tissue engineering. Part B, Reviews.

[24]  M. Marcacci,et al.  A one-step treatment for chondral and osteochondral knee defects: clinical results of a biomimetic scaffold implantation at 2 years of follow-up , 2014, Journal of Materials Science: Materials in Medicine.

[25]  Dong-Jin Yoo,et al.  Heterogeneous porous scaffold design using the continuous transformations of triply periodic minimal surface models , 2013 .

[26]  R. Reis,et al.  Cartilage and Bone Regeneration—How Close Are We to Bedside? , 2016 .

[27]  Kyriacos A Athanasiou,et al.  Chondroitinase ABC treatment results in greater tensile properties of self-assembled tissue-engineered articular cartilage. , 2009, Tissue engineering. Part A.

[28]  D. Kaplan,et al.  Porosity of 3D biomaterial scaffolds and osteogenesis. , 2005, Biomaterials.

[29]  D. Flanigan,et al.  New and Emerging Techniques in Cartilage Repair: Other Scaffold-Based Cartilage Treatment Options , 2013 .