Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene.

[1]  E. Arner,et al.  Adipocyte lipases and defect of lipolysis in human obesity. , 2005, Diabetes.

[2]  Frank Eisenhaber,et al.  Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase , 2004, Science.

[3]  W. Saris,et al.  Impaired β-adrenergically mediated lipolysis in skeletal muscle of obese subjects , 2004, Diabetologia.

[4]  L. Qi,et al.  Genetic variation at the hormone sensitive lipase: gender‐specific association with plasma lipid and glucose concentrations , 2004, Clinical genetics.

[5]  C. Bouchard,et al.  Obesity – is it a genetic disorder? , 2003, Journal of internal medicine.

[6]  M. Rydén,et al.  The hormone‐sensitive lipase i6 gene polymorphism and body fat accumulation , 2002, European journal of clinical investigation.

[7]  P. Talmud,et al.  Variation in the promoter of the human hormone sensitive lipase gene shows gender specific effects on insulin and lipid levels: results from the Ely study. , 2001, Biochimica et biophysica acta.

[8]  E. Blaak,et al.  Gender differences in fat metabolism , 2001, Current opinion in clinical nutrition and metabolic care.

[9]  N. Pedersen,et al.  A common hormone-sensitive lipase i6 gene polymorphism is associated with decreased human adipocyte lipolytic function. , 2001, Diabetes.

[10]  W. Saris,et al.  Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise. , 2000, Diabetes.

[11]  W. Saris,et al.  Beta-adrenergically stimulated fat oxidation is diminished in middle-aged compared to young subjects. , 1999, The Journal of clinical endocrinology and metabolism.

[12]  D J Schaid,et al.  Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions. , 1999, American journal of epidemiology.

[13]  P. Amouyel,et al.  β2-adrenoceptor gene polymorphism, body weight, and physical activity , 1999, The Lancet.

[14]  P. Arner Catecholamine-induced lipolysis in obesity , 1999, International Journal of Obesity.

[15]  M. Walker,et al.  Identification of genetic variation in the human hormone-sensitive lipase gene and 5' sequences: homology of 5' sequences with mouse promoter and identification of potential regulatory elements. , 1998, Biochemical and biophysical research communications.

[16]  L. Groop,et al.  The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity , 1998, Diabetologia.

[17]  C. Fizames,et al.  Human Hormone-Sensitive Lipase: Genetic Mapping, Identification of a New Dinucleotide Repeat, and Association With Obesity and NIDDM , 1998, Diabetes.

[18]  N. Risch,et al.  A comparison of linkage disequilibrium measures for fine-scale mapping. , 1995, Genomics.

[19]  H. Mohrenweiser,et al.  The hormone-sensitive lipase (LIPE) gene located on chromosome 19q13.1-->13.2 is not duplicated on 19p13.3. , 1995, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[20]  W. Saris,et al.  Beta-adrenergic stimulation of energy expenditure and forearm skeletal muscle metabolism in lean and obese men. , 1994, The American journal of physiology.

[21]  W. Saris,et al.  beta-Adrenergic stimulation of skeletal muscle metabolism in relation to weight reduction in obese men. , 1994, The American journal of physiology.

[22]  S. Reynisdottir,et al.  Multiple lipolysis defects in the insulin resistance (metabolic) syndrome. , 1994, The Journal of clinical investigation.

[23]  M. Jensen,et al.  Fatty acid kinetic responses to exercise. Effects of obesity, body fat distribution, and energy-restricted diet. , 1993, The Journal of clinical investigation.

[24]  T. Mohandas,et al.  Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3. , 1988, Science.

[25]  J. B. Weir New methods for calculating metabolic rate with special reference to protein metabolism , 1949, The Journal of physiology.

[26]  Y. Chagnon,et al.  The hormone-sensitive lipase gene and body composition: the HERITAGE Family Study , 2002, International Journal of Obesity.

[27]  E. Wouters,et al.  beta-Adrenoceptor-mediated thermogenesis and lipolysis in patients with chronic obstructive pulmonary disease. , 2001, American journal of physiology. Endocrinology and metabolism.

[28]  B. Wolffenbuttel,et al.  The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society , 2000 .

[29]  W. Saris,et al.  Substrate utilization and thermogenic responses to β-adrenergic stimulation in obese subjects with NIDDM , 1999, International Journal of Obesity.

[30]  W. Siri,et al.  The gross composition of the body. , 1956, Advances in biological and medical physics.