Sensory Maps on the Move

The auditory and visual space maps of barn owls are closely connected, enabling the birds to precisely locate prey. If prism spectacles are placed over the eyes of juvenile owls, the visual and auditory space maps rearrange so that both maps remain ALIGNED. In his Perspective, [Michael Stryke][1] r explains new findings reported in this issue ([Zheng and Knudsen][2]) that show that this neural plasticity results not only from the addition of new inputs but also from the selective inhibition of the inputs responsible for the old map, the connections for which remain in place but are overwhelmed by new inhibition. He further posits that combined plasticity of both excitatory and inhibitory inputs may be involved in rearrangements of other types of sensory maps. [1]: http://www.sciencemag.org/cgi/content/full/284/5416/925 [2]: http://www.sciencemag.org/cgi/content/short/284/5416/962

[1]  M. Stryker,et al.  Local GABA circuit control of experience-dependent plasticity in developing visual cortex. , 1998, Science.

[2]  D. Feldman,et al.  An Anatomical Basis for Visual Calibration of the Auditory Space Map in the Barn Owl’s Midbrain , 1997, The Journal of Neuroscience.

[3]  E I Knudsen,et al.  Newly Learned Auditory Responses Mediated by NMDA Receptors in the Owl Inferior Colliculus , 1996, Science.

[4]  E. Knudsen,et al.  Functional selection of adaptive auditory space map by GABAA-mediated inhibition. , 1999, Science.

[5]  Colin Blakemore,et al.  The role of GABAergic inhibition in the cortical effects of monocular deprivation , 1981, Nature.

[6]  K Saberi,et al.  How do owls localize interaurally phase-ambiguous signals? , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[7]  M. Konishi The neural algorithm for sound localization in the owl. , 1990, Harvey lectures.

[8]  H. Wagner,et al.  Representation of interaural time difference in the central nucleus of the barn owl's inferior colliculus , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[9]  G. Recanzone,et al.  Adaptive mechanisms in cortical networks underlying cortical contributions to learning and nondeclarative memory. , 1990, Cold Spring Harbor symposia on quantitative biology.

[10]  S. Nelson,et al.  BDNF Has Opposite Effects on the Quantal Amplitude of Pyramidal Neuron and Interneuron Excitatory Synapses , 1998, Neuron.