NSUN2 stimulates tumor progression via enhancing TIAM2 mRNA stability in pancreatic cancer
暂无分享,去创建一个
W. Xue | R. Sun | Yun Wang | G. Cui | Jianhao Li | Liwen Liu | Yize Zhang | Zihui Dong | Yu Chen | Guizhen Zhang
[1] F. Dong,et al. NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration , 2022, Epigenetics.
[2] Holger Knaut,et al. Focal adhesion-mediated cell anchoring and migration: from in vitro to in vivo. , 2022, Development.
[3] Peng-Chieh Chen,et al. RNA bisulfite sequencing reveals NSUN2-mediated suppression of epithelial differentiation in pancreatic cancer , 2022, Oncogene.
[4] Mariana Cooke. Novel insights into the RTK-dependent metastatic phenotype of KRAS-mutant lung adenocarcinoma , 2021, Molecular & Cellular Oncology.
[5] M. Kazanietz,et al. FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma. , 2021, Cell reports.
[6] Libing Wang,et al. m5C RNA methyltransferase-related gene NSUN4 stimulates malignant progression of hepatocellular carcinoma and can be a prognostic marker. , 2021, Cancer biomarkers : section A of Disease markers.
[7] Y. Hu,et al. NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation , 2021, Cell Death & Disease.
[8] D. Lin,et al. NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization , 2021, Oncogene.
[9] Xiaoting Lin,et al. lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling , 2021, Molecular therapy : the journal of the American Society of Gene Therapy.
[10] Huaizhi Wang,et al. N6-methyladenosine (m6A) in pancreatic cancer: Regulatory mechanisms and future direction , 2021, International journal of biological sciences.
[11] A. Jemal,et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries , 2021, CA: a cancer journal for clinicians.
[12] S. Blanco,et al. The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities , 2021, Molecular Cancer.
[13] Yu-Sheng Chen,et al. Dynamic transcriptomic m5C and its regulatory role in RNA processing , 2021, Wiley interdisciplinary reviews. RNA.
[14] Chengxi Liu,et al. Elevated TIAM2 expression promotes tumor progression and is associated with unfavorable prognosis in pancreatic cancer , 2020, Scandinavian journal of gastroenterology.
[15] R. Kohli,et al. TET-mediated 5-methylcytosine oxidation in tRNA promotes translation , 2020, The Journal of biological chemistry.
[16] Xin Xu,et al. NSun2 promotes cell migration through methylating autotaxin mRNA , 2020, The Journal of Biological Chemistry.
[17] H. Cui,et al. Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma , 2020, Oncogene.
[18] J. T. Tseng,et al. TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis , 2020, Cancers.
[19] Yun Feng,et al. RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner , 2020, Molecular Cancer.
[20] Jiang Chang,et al. N6-methyladenosine mRNA methylation of PIK3CB regulates AKT signalling to promote PTEN-deficient pancreatic cancer progression , 2020, Gut.
[21] T. Kouzarides,et al. Role of RNA modifications in cancer , 2020, Nature Reviews Cancer.
[22] Ming-Hai Wang,et al. RNA methyltransferase NSUN2 promotes gastric cancer cell proliferation by repressing p57Kip2 by an m5C-dependent manner , 2020, Cell Death & Disease.
[23] Heshui Wu,et al. Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway , 2020, Molecular therapy oncolytics.
[24] T. Preiss,et al. Multiple links between 5-methylcytosine content of mRNA and translation , 2020, BMC Biology.
[25] Shikui Tu,et al. Integrated analysis of transcriptome-wide m6A methylome of osteosarcoma stem cells enriched by chemotherapy. , 2019, Epigenomics.
[26] T. H. Nguyen,et al. The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 , 2019, The lancet. Gastroenterology & hepatology.
[27] Zheng Wang,et al. NOP2/Sun RNA methyltransferase 2 promotes tumor progression via its interacting partner RPL6 in gallbladder carcinoma , 2019, Cancer science.
[28] Jun Xia,et al. RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay. , 2019, Molecular cell.
[29] R. Sun,et al. N6-methyladenosine-related Genomic Targets are Altered in Breast Cancer Tissue and Associated with Poor Survival , 2019, Journal of Cancer.
[30] Dan Xie,et al. 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs , 2019, Nature Cell Biology.
[31] H. Cui,et al. Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells. , 2019, Epigenomics.
[32] M. Bohnsack,et al. Eukaryotic 5-methylcytosine (m5C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease , 2019, Genes.
[33] P. Gallo,et al. Promoting genetics in non-alcoholic fatty liver disease: Combined risk score through polymorphisms and clinical variables , 2018, World journal of gastroenterology.
[34] K. Hahn,et al. STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap , 2018, Nature Communications.
[35] N. Gray,et al. Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia. , 2017, Blood.
[36] Samir Adhikari,et al. 5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader , 2017, Cell Research.
[37] T. N. Gaitanos,et al. Tiam–Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion , 2016, The Journal of cell biology.
[38] Steven L Salzberg,et al. HISAT: a fast spliced aligner with low memory requirements , 2015, Nature Methods.
[39] Tsonwin Hai,et al. PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS ATF3 is a novel regulator of mouse neutrophil migration , 2016 .
[40] Juntao Liu,et al. TIAM2 enhances non-small cell lung cancer cell invasion and motility. , 2013, Asian Pacific journal of cancer prevention : APJCP.
[41] E. Nestler,et al. diffReps: Detecting Differential Chromatin Modification Sites from ChIP-seq Data with Biological Replicates , 2013, PloS one.
[42] M. Tatsuka,et al. Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers. , 2012, DNA and cell biology.
[43] Kung-Chia Young,et al. Expression of T‐cell lymphoma invasion and metastasis 2 (TIAM2) promotes proliferation and invasion of liver cancer , 2012, International journal of cancer.
[44] Chuan He,et al. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine , 2011, Science.
[45] A. Malliri,et al. The Rac activator STEF (Tiam2) regulates cell migration by microtubule‐mediated focal adhesion disassembly , 2010, EMBO reports.
[46] Clifford A. Meyer,et al. Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.
[47] F. Watt,et al. The RNA Methyltransferase Misu (NSun2) Mediates Myc-Induced Proliferation and Is Upregulated in Tumors , 2006, Current Biology.
[48] E. Kim,et al. Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1. , 1999, Genomics.