Neurotechnologies for Human Cognitive Augmentation: Current State of the Art and Future Prospects

Recent advances in neuroscience have paved the way to innovative applications that cognitively augment and enhance humans in a variety of contexts. This paper aims at providing a snapshot of the current state of the art and a motivated forecast of the most likely developments in the next two decades. Firstly, we survey the main neuroscience technologies for both observing and influencing brain activity, which are necessary ingredients for human cognitive augmentation. We also compare and contrast such technologies, as their individual characteristics (e.g., spatio-temporal resolution, invasiveness, portability, energy requirements, and cost) influence their current and future role in human cognitive augmentation. Secondly, we chart the state of the art on neurotechnologies for human cognitive augmentation, keeping an eye both on the applications that already exist and those that are emerging or are likely to emerge in the next two decades. Particularly, we consider applications in the areas of communication, cognitive enhancement, memory, attention monitoring/enhancement, situation awareness and complex problem solving, and we look at what fraction of the population might benefit from such technologies and at the demands they impose in terms of user training. Thirdly, we briefly review the ethical issues associated with current neuroscience technologies. These are important because they may differentially influence both present and future research on (and adoption of) neurotechnologies for human cognitive augmentation: an inferior technology with no significant ethical issues may thrive while a superior technology causing widespread ethical concerns may end up being outlawed. Finally, based on the lessons learned in our analysis, using past trends and considering other related forecasts, we attempt to forecast the most likely future developments of neuroscience technology for human cognitive augmentation and provide informed recommendations for promising future research and exploitation avenues.

[1]  Jörn M. Horschig,et al.  Hypothesis-driven methods to augment human cognition by optimizing cortical oscillations , 2014, Front. Syst. Neurosci..

[2]  N. Squires,et al.  Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man. , 1975, Electroencephalography and clinical neurophysiology.

[3]  J. Reis,et al.  Pre-Trial EEG-Based Single-Trial Motor Performance Prediction to Enhance Neuroergonomics for a Hand Force Task , 2016, Front. Hum. Neurosci..

[4]  Xu Cui,et al.  NIRS-based hyperscanning reveals increased interpersonal coherence in superior frontal cortex during cooperation , 2012, NeuroImage.

[5]  Kazuhiko Sagara,et al.  Portable single-channel NIRS-based BMI system for motor disabilities' communication tools , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  Nicolas Y. Masse,et al.  Neural Point-and-Click Communication by a Person With Incomplete Locked-In Syndrome , 2015, Neurorehabilitation and neural repair.

[7]  N. Birbaumer,et al.  Enhancement of Planning Ability by Transcranial Direct Current Stimulation , 2009, The Journal of Neuroscience.

[8]  W. H. Dobelle,et al.  Artificial vision for the blind by electrical stimulation of the visual cortex. , 1979, Neurosurgery.

[9]  I. Fried,et al.  Memory enhancement and deep-brain stimulation of the entorhinal area. , 2012, The New England journal of medicine.

[10]  Bijan Pesaran,et al.  Investigating large-scale brain dynamics using field potential recordings: analysis and interpretation , 2018, Nature Neuroscience.

[11]  Lynne M. Coventry,et al.  Human Factors , 2010, Handbook of Financial Cryptography and Security.

[12]  Davide Valeriani,et al.  Past and Future of Multi-Mind Brain-Computer Interfaces , 2018 .

[13]  S. Eickhoff,et al.  Sustaining attention to simple tasks: a meta-analytic review of the neural mechanisms of vigilant attention. , 2013, Psychological bulletin.

[14]  Thomas F Münte,et al.  Errorless and errorful learning modulated by transcranial direct current stimulation , 2011, BMC Neuroscience.

[15]  T. Ilić,et al.  Transcranial direct current stimulation , 2008, Clinical Neurophysiology.

[16]  J. Rothwell,et al.  Variability in Response to Transcranial Direct Current Stimulation of the Motor Cortex , 2014, Brain Stimulation.

[17]  Elisabeth Hildt,et al.  What will this do to me and my brain? Ethical issues in brain-to-brain interfacing , 2015, Front. Syst. Neurosci..

[18]  Daniel J. Strauss,et al.  Neurofeedback by neural correlates of auditory selective attention as possible application for tinnitus therapies , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[19]  Ramon J. Aldag,et al.  Decision Making: A Psychological Analysis of Conflict , 1980 .

[20]  Wolfgang Rosenstiel,et al.  Online use of error-related potentials in healthy users and people with severe motor impairment increases performance of a P300-BCI , 2012, Clinical Neurophysiology.

[21]  Luca T. Mainardi,et al.  Online Detection of P300 and Error Potentials in a BCI Speller , 2010, Comput. Intell. Neurosci..

[22]  William L. Farmer,et al.  From ABLE to TAPAS: A New Generation of Personality Tests to Support Military Selection and Classification Decisions , 2014 .

[23]  Steven Baker,et al.  Mapping Brain Activity During Loss of Situation Awareness , 2014, Hum. Factors.

[24]  G. Woodman,et al.  Event-related potential studies of attention , 2000, Trends in Cognitive Sciences.

[25]  Arto Nurmikko,et al.  An implantable wireless neural interface for recording cortical circuit dynamics in moving primates , 2013, Journal of neural engineering.

[26]  Glenn F. Wilson,et al.  Performance Enhancement in an Uninhabited Air Vehicle Task Using Psychophysiologically Determined Adaptive Aiding , 2007, Hum. Factors.

[27]  Vince D. Calhoun,et al.  TDCS guided using fMRI significantly accelerates learning to identify concealed objects , 2012, NeuroImage.

[28]  J. Polich,et al.  On the relationship between EEG and P300: individual differences, aging, and ultradian rhythms. , 1997, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[29]  Paul B. Fitzgerald,et al.  Investigating the Role of Current Strength in tDCS Modulation of Working Memory Performance in Healthy Controls , 2011, Front. Psychiatry.

[30]  R. Wennberg,et al.  Memory enhancement induced by hypothalamic/fornix deep brain stimulation , 2008, Annals of neurology.

[31]  R. Parasuraman,et al.  Auditory evoked potentials and divided attention. , 1978, Psychophysiology.

[32]  Hubert Cecotti,et al.  A Self-Paced and Calibration-Less SSVEP-Based Brain–Computer Interface Speller , 2010, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[33]  Stephan Waldert,et al.  Invasive vs. Non-Invasive Neuronal Signals for Brain-Machine Interfaces: Will One Prevail? , 2016, Front. Neurosci..

[34]  C. Miniussi,et al.  Transcranial brain stimulation studies of episodic memory in young adults, elderly adults and individuals with memory dysfunction: A review , 2012, Brain Stimulation.

[35]  Brendan Z. Allison,et al.  Journal of Neuroscience Methods , 2022 .

[36]  R. Hampson,et al.  Ceramic-based microelectrode neuronal recordings in the rat and monkey , 2003, Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439).

[37]  D. McLoughlin,et al.  Objective Cognitive Performance Associated with Electroconvulsive Therapy for Depression: A Systematic Review and Meta-Analysis , 2010, Biological Psychiatry.

[38]  Dean J Krusienski,et al.  Control of a Visual Keyboard Using an Electrocorticographic Brain–Computer Interface , 2011, Neurorehabilitation and neural repair.

[39]  Paul A. Pope,et al.  Task-Specific Facilitation of Cognition by Anodal Transcranial Direct Current Stimulation of the Prefrontal Cortex , 2015, Cerebral cortex.

[40]  A. Belyavin,et al.  Changes in electrical activity of the brain with vigilance. , 1987, Electroencephalography and clinical neurophysiology.

[41]  G. Riva,et al.  The use of P300-based BCIs in amyotrophic lateral sclerosis: from augmentative and alternative communication to cognitive assessment , 2012, Brain and behavior.

[42]  Anthony J. Ries,et al.  A Cognitive Systems Engineering Evaluation of a Tool to Aid Imagery Analysts , 2015 .

[43]  Christa Neuper,et al.  Future prospects of ERD/ERS in the context of brain-computer interface (BCI) developments. , 2006, Progress in brain research.

[44]  Chris Berka,et al.  Training: Neural systems and intelligence applications , 2011 .

[45]  Anton Nijholt,et al.  Multi-Brain Games: Cooperation and Competition , 2013, HCI.

[46]  P. Sajda,et al.  Response error correction-a demonstration of improved human-machine performance using real-time EEG monitoring , 2003, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[47]  G. Pfurtscheller,et al.  Conversion of EEG activity into cursor movement by a brain-computer interface (BCI) , 2004, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[48]  Janet A. Sniezek,et al.  Groups under uncertainty: An examination of confidence in group decision making☆ , 1992 .

[49]  Ronald H. Stevens,et al.  Neurotechnology to Accelerate Learning: During Marksmanship Training , 2012, IEEE Pulse.

[50]  Wei Tech Ang,et al.  Mobile EEG-based situation awareness recognition for air traffic controllers , 2017, 2017 IEEE International Conference on Systems, Man, and Cybernetics (SMC).

[51]  Felipe Fregni,et al.  Visual memory improved by non-invasive brain stimulation , 2010, Brain Research.

[52]  Rajesh P. N. Rao,et al.  Playing 20 Questions with the Mind: Collaborative Problem Solving by Humans Using a Brain-to-Brain Interface , 2015, PloS one.

[53]  S. Quartz,et al.  Getting to Know You: Reputation and Trust in a Two-Person Economic Exchange , 2005, Science.

[54]  Vincent P. Clark,et al.  The ethical, moral, and pragmatic rationale for brain augmentation , 2014, Front. Syst. Neurosci..

[55]  F. Cincotti,et al.  High Resolution EEG Hyperscanning During a Card Game , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[56]  Miguel A. L. Nicolelis,et al.  Real-time control of a robot arm using simultaneously recorded neurons in the motor cortex , 1999, Nature Neuroscience.

[57]  S. Rothmann,et al.  THE BIG FIVE PERSONALITY DIMENSIONS AND JOB PERFORMANCE , 2003 .

[58]  R. Sparrow on Human Enhancement , 2011 .

[59]  Katsuhiro Kobayashi,et al.  Memory enhancement and deep-brain stimulation of the entorhinal area. , 2012, The New England journal of medicine.

[60]  David M. Santucci,et al.  Learning to Control a Brain–Machine Interface for Reaching and Grasping by Primates , 2003, PLoS biology.

[61]  S Pozzi,et al.  A passive brain-computer interface application for the mental workload assessment on professional air traffic controllers during realistic air traffic control tasks. , 2016, Progress in brain research.

[62]  Robert T. Knight,et al.  Lapses in a Prefrontal-Extrastriate Preparatory Attention Network Predict Mistakes , 2006, Journal of Cognitive Neuroscience.

[63]  G. Pfurtscheller,et al.  Brain-Computer Interfaces for Communication and Control. , 2011, Communications of the ACM.

[64]  Ricardo Chavarriaga,et al.  The timing of exploratory decision-making revealed by single-trial topographic EEGanalyses , 2012, NeuroImage.

[65]  N. Bostrom,et al.  Ethical issues in human enhancement , 2007 .

[66]  N. Birbaumer,et al.  Brain-computer communication: self-regulation of slow cortical potentials for verbal communication. , 2001, Archives of physical medicine and rehabilitation.

[67]  Mica R. Endsley,et al.  Toward a Theory of Situation Awareness in Dynamic Systems , 1995, Hum. Factors.

[68]  Cyrus K. Foroughi,et al.  Activation and inhibition of posterior parietal cortex have bi-directional effects on spatial errors following interruptions , 2015, Front. Syst. Neurosci..

[69]  Colin F Camerer,et al.  Agent-Specific Responses in the Cingulate Cortex During Economic Exchanges , 2006, Science.

[70]  Christa Neuper,et al.  An asynchronously controlled EEG-based virtual keyboard: improvement of the spelling rate , 2004, IEEE Transactions on Biomedical Engineering.

[71]  Nico M Schmidt,et al.  Online detection of error-related potentials boosts the performance of mental typewriters , 2012, BMC Neuroscience.

[72]  José del R. Millán,et al.  An Introduction to Brain-Computer Interfacing , 2007 .

[73]  Rajesh P. N. Rao,et al.  Electrocorticography-based brain computer Interface-the seattle experience , 2006, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[74]  Thorsten O. Zander,et al.  Passive Brain–Computer Interfaces , 2018 .

[75]  Dawn M. Taylor,et al.  Direct Cortical Control of 3D Neuroprosthetic Devices , 2002, Science.

[76]  D J McFarland,et al.  An EEG-based brain-computer interface for cursor control. , 1991, Electroencephalography and clinical neurophysiology.

[77]  Marco Ferrari,et al.  A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application , 2012, NeuroImage.

[78]  Reframing Human Enhancement: A Population Health Perspective , 2017, Front. Sociol..

[79]  Riccardo Poli,et al.  Group Augmentation in Realistic Visual-Search Decisions via a Hybrid Brain-Computer Interface , 2017, Scientific Reports.

[80]  P. Goldman-Rakic,et al.  Segregation of working memory functions within the dorsolateral prefrontal cortex , 2000, Experimental Brain Research.

[81]  José del R. Millán,et al.  BNCI Horizon 2020: Towards a Roadmap for the BCI Community , 2015 .

[82]  F. Guenther,et al.  A Wireless Brain-Machine Interface for Real-Time Speech Synthesis , 2009, PloS one.

[83]  Joel S. Warm,et al.  Enhancing vigilance in operators with prefrontal cortex transcranial direct current stimulation (tDCS) , 2014, NeuroImage.

[84]  Theodore W. Berger,et al.  The Neurobiological Basis of Cognition: Identification by Multi-Input, Multioutput Nonlinear Dynamic Modeling , 2010, Proceedings of the IEEE.

[85]  Å. Hammar,et al.  Cognitive Functioning in Major Depression – A Summary , 2009, Front. Hum. Neurosci..

[86]  Rajesh P. N. Rao,et al.  BrainNet: A Multi-Person Brain-to-Brain Interface for Direct Collaboration Between Brains , 2018, ArXiv.

[87]  A. Mele Direct control , 2017 .

[88]  Gereon R. Fink,et al.  Enhancing language performance with non-invasive brain stimulation—A transcranial direct current stimulation study in healthy humans , 2008, Neuropsychologia.

[89]  A. Murata,et al.  Assessment of mental fatigue during VDT task using event-related potential (P300) , 2000, Proceedings 9th IEEE International Workshop on Robot and Human Interactive Communication. IEEE RO-MAN 2000 (Cat. No.00TH8499).

[90]  Robert E. Hampson,et al.  Prefrontal cortical recordings with biomorphic MEAs reveal complex columnar-laminar microcircuits for BCI/BMI implementation , 2015, Journal of Neuroscience Methods.

[91]  Ethan R. Buch,et al.  Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation , 2009, Proceedings of the National Academy of Sciences.

[92]  B. Cheeran,et al.  Inter-individual Variability in Response to Non-invasive Brain Stimulation Paradigms , 2014, Brain Stimulation.

[93]  M R Endsley,et al.  Sources of situation awareness errors in aviation. , 1996, Aviation, space, and environmental medicine.

[94]  P.R. Kennedy,et al.  Computer control using human intracortical local field potentials , 2004, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[95]  Theodore W Berger,et al.  A cortical neural prosthesis for restoring and enhancing memory , 2011, Journal of neural engineering.

[96]  Eduardo Salas,et al.  Making decisions under stress: Implications for individual and team training. , 1998 .

[97]  H. Price Past and future , 1990, Nature.

[98]  K. R. Ridderinkhof,et al.  Error-related brain potentials are differentially related to awareness of response errors: evidence from an antisaccade task. , 2001, Psychophysiology.

[99]  Alfie Gleeson,et al.  Mapping a brain. , 2018, BioTechniques.

[100]  Rajesh P. N. Rao,et al.  A Direct Brain-to-Brain Interface in Humans , 2014, PloS one.

[101]  Weidong Chen,et al.  Rapid face recognition based on single-trial event-related potential detection over multiple brains , 2015, 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER).

[102]  R A Normann,et al.  The Utah intracortical Electrode Array: a recording structure for potential brain-computer interfaces. , 1997, Electroencephalography and clinical neurophysiology.

[103]  E. Sellers,et al.  How many people are able to control a P300-based brain–computer interface (BCI)? , 2009, Neuroscience Letters.

[104]  S. Perrey,et al.  Does a Combination of Virtual Reality, Neuromodulation and Neuroimaging Provide a Comprehensive Platform for Neurorehabilitation? – A Narrative Review of the Literature , 2016, Front. Hum. Neurosci..

[105]  Atsuo Murata,et al.  Evaluation of mental fatigue using feature parameter extracted from event-related potential , 2002 .

[106]  J. Booth,et al.  Weighing the Cost and Benefit of Transcranial Direct Current Stimulation on Different Reading Subskills , 2016, Front. Neurosci..

[107]  Gottfried Schlaug,et al.  Anodal Transcranial Direct Current Stimulation of the Prefrontal Cortex Enhances Complex Verbal Associative Thought , 2009, Journal of Cognitive Neuroscience.

[108]  Selma Supek,et al.  Magnetoencephalography: From Signals to Dynamic Cortical Networks , 2014 .

[109]  Richard A. Andersen,et al.  A collaborative BCI approach to autonomous control of a prosthetic limb system , 2014, 2014 IEEE International Conference on Systems, Man, and Cybernetics (SMC).

[110]  Francisco J. Pelayo,et al.  A high performance SSVEP-BCI without gazing , 2010, The 2010 International Joint Conference on Neural Networks (IJCNN).

[111]  Chris Berka,et al.  Neural Systems in Intelligence and Training Applications , 2014 .

[112]  Daniel Sánchez Morillo,et al.  Dry EEG Electrodes , 2014, Sensors.

[113]  Fabio Babiloni,et al.  Human Factors and Neurophysiological Metrics in Air Traffic Control: A Critical Review , 2017, IEEE Reviews in Biomedical Engineering.

[114]  J. Polich Updating P300: An integrative theory of P3a and P3b , 2007, Clinical Neurophysiology.

[115]  E. J. Tehovnik,et al.  Transfer of information by BMI , 2013, Neuroscience.

[116]  C. Madan Augmented memory: a survey of the approaches to remembering more , 2014, Front. Syst. Neurosci..

[117]  Riccardo Poli,et al.  Event-Related Potentials induced by cuts in feature movies and their exploitation for understanding cut efficacy , 2015, 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER).

[118]  W. Dobelle,et al.  Phosphenes produced by electrical stimulation of human occipital cortex, and their application to the development of a prosthesis for the blind , 1974, The Journal of physiology.

[119]  S. Gronlund,et al.  Situation Awareness , 2006 .

[120]  Riccardo Poli,et al.  Collaborative brain-computer interfaces for the automatic classification of images , 2013, 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER).

[121]  P R Kennedy,et al.  Direct control of a computer from the human central nervous system. , 2000, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[122]  F Cincotti,et al.  Simultaneous estimation of cortical activity during social interactions by using EEG hyperscannings , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[123]  Riccardo Poli,et al.  Towards cooperative brain-computer interfaces for space navigation , 2013, IUI '13.

[124]  Raja Parasuraman,et al.  Enhancing dual-task performance with verbal and spatial working memory training: Continuous monitoring of cerebral hemodynamics with NIRS , 2014, NeuroImage.

[125]  Sergio P. Rigonatti,et al.  Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory , 2005, Experimental Brain Research.

[126]  Mihaly Benda,et al.  Brain–Computer Interface Spellers: A Review , 2018, Brain sciences.

[127]  Gerwin Schalk,et al.  Rapid Communication with a “P300” Matrix Speller Using Electrocorticographic Signals (ECoG) , 2010, Front. Neurosci..

[128]  Luca Citi,et al.  Augmenting group decision making accuracy in a realistic environment using collaborative brain-computer interfaces based on error-related potentials , 2018 .

[129]  Timothy E. J. Behrens,et al.  Choice, uncertainty and value in prefrontal and cingulate cortex , 2008, Nature Neuroscience.

[130]  Chang S. Nam,et al.  A Collaborative Brain-Computer Interface (BCI) for ALS Patients , 2015 .

[131]  Fanglin Chen,et al.  A novel hybrid BCI speller based on the incorporation of SSVEP into the P300 paradigm , 2013, Journal of neural engineering.

[132]  Eric W. Sellers,et al.  Noninvasive brain-computer interface enables communication after brainstem stroke , 2014, Science Translational Medicine.

[133]  Edward M. Hitchcock,et al.  Automation cueing modulates cerebral blood flow and vigilance in a simulated air traffic control task , 2003 .

[134]  M. Nitsche,et al.  Facilitation of Implicit Motor Learning by Weak Transcranial Direct Current Stimulation of the Primary Motor Cortex in the Human , 2003, Journal of Cognitive Neuroscience.

[135]  Fang Fang,et al.  Lie detection with contingent negative variation. , 2003, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[136]  M. Maragkou,et al.  Real-time control , 2014 .

[137]  George I. Christopoulos,et al.  Risk-dependent reward value signal in human prefrontal cortex , 2009, Proceedings of the National Academy of Sciences.

[138]  Tanja Schultz,et al.  Brain-to-text: decoding spoken phrases from phone representations in the brain , 2015, Front. Neurosci..

[139]  Miguel A. L. Nicolelis,et al.  Building an organic computing device with multiple interconnected brains , 2015, Scientific Reports.

[140]  N. J. Davis,et al.  “Non-invasive” brain stimulation is not non-invasive , 2013, Front. Syst. Neurosci..

[141]  Roberta Sellaro,et al.  Transcranial Alternating Current Stimulation , 2017 .

[142]  Giacomo Koch,et al.  Reading changes in children and adolescents with dyslexia after transcranial direct current stimulation , 2016, Neuroreport.

[143]  Chang-Hwan Im,et al.  Development of an SSVEP-based BCI spelling system adopting a QWERTY-style LED keyboard , 2012, Journal of Neuroscience Methods.

[144]  C. Epstein Promise and perspective in transcranial magnetic stimulation , 2014, Clinical Neurophysiology.

[145]  Brian A. Lopez,et al.  P3a from visual stimuli: task difficulty effects. , 2006, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[146]  R. Parasuraman,et al.  Continuous monitoring of brain dynamics with functional near infrared spectroscopy as a tool for neuroergonomic research: empirical examples and a technological development , 2013, Front. Hum. Neurosci..

[147]  L. Astolfi,et al.  Social neuroscience and hyperscanning techniques: Past, present and future , 2014, Neuroscience & Biobehavioral Reviews.

[148]  Gyrd Skraaning,et al.  Distinguishing Three Accounts of Situation Awareness based on their Domains of Origin , 2013 .

[149]  Yang Yu,et al.  A Dynamically Optimized SSVEP Brain–Computer Interface (BCI) Speller , 2015, IEEE Transactions on Biomedical Engineering.

[150]  Thibault Gateau,et al.  Processing Functional Near Infrared Spectroscopy Signal with a Kalman Filter to Assess Working Memory during Simulated Flight , 2016, Front. Hum. Neurosci..

[151]  Kevin A. Brown,et al.  Development of semi-chronic microdrive system for large-scale circuit mapping in macaque mesolimbic and basal ganglia systems , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[152]  Alvaro Pascual-Leone,et al.  Temporal Lobe Cortical Electrical Stimulation during the Encoding and Retrieval Phase Reduces False Memories , 2009, PloS one.

[153]  N. Birbaumer,et al.  A New Method for Self-Regulation of Slow Cortical Potentials in a Timed Paradigm , 1997, Applied psychophysiology and biofeedback.

[154]  M. Lavidor,et al.  Transcranial Alternating Current Stimulation Increases Risk-Taking Behavior in the Balloon Analog Risk Task , 2011, Front. Neurosci..

[155]  N. Birbaumer,et al.  The thought translation device: a neurophysiological approach to communication in total motor paralysis , 1999, Experimental Brain Research.

[156]  Allan W. Snyder,et al.  Brain stimulation enables the solution of an inherently difficult problem , 2012, Neuroscience Letters.

[157]  L. Tashi,et al.  Transfer of Information. , 1986 .

[158]  Peng Yuan,et al.  Study on an online collaborative BCI to accelerate response to visual targets , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[159]  C. Freitag,et al.  Neurofeedback of Slow Cortical Potentials in Children with Attention-Deficit/Hyperactivity Disorder: A Multicenter Randomized Trial Controlling for Unspecific Effects , 2017, Front. Hum. Neurosci..

[160]  S. Yoo,et al.  Non-Invasive Brain-to-Brain Interface (BBI): Establishing Functional Links between Two Brains , 2013, PloS one.

[161]  Riccardo Poli,et al.  Collaborative brain-computer interfaces for target localisation in rapid serial visual presentation , 2014, 2014 6th Computer Science and Electronic Engineering Conference (CEEC).

[162]  Frank H. Guenther,et al.  Brain-computer interfaces for speech communication , 2010, Speech Commun..

[163]  R Parasuraman,et al.  Brain events underlying detection and recognition of weak sensory signals. , 1980, Science.

[164]  H. Oka,et al.  A new planar multielectrode array for extracellular recording: application to hippocampal acute slice , 1999, Journal of Neuroscience Methods.

[165]  Tzyy-Ping Jung,et al.  A Collaborative Brain-Computer Interface for Improving Human Performance , 2011, PloS one.

[166]  Shirley M Coyle,et al.  Brain–computer interface using a simplified functional near-infrared spectroscopy system , 2007, Journal of neural engineering.

[167]  M. Nitsche,et al.  Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation , 2000, The Journal of physiology.

[168]  M. Lavidor,et al.  Improved reading measures in adults with dyslexia following transcranial direct current stimulation treatment , 2015, Neuropsychologia.

[169]  N. Bolognini,et al.  Brain polarization of parietal cortex augments training-induced improvement of visual exploratory and attentional skills , 2010, Brain Research.

[170]  Mikhail A. Lebedev,et al.  Neurofeedback Therapy for Enhancing Visual Attention: State-of-the-Art and Challenges , 2016, Front. Neurosci..

[171]  Laurens R. Krol,et al.  Passive Brain–Computer Interfaces: A Perspective on Increased Interactivity , 2018 .

[172]  Adrian Stoica MultiMind: Multi-Brain Signal Fusion to Exceed the Power of a Single Brain , 2012, 2012 Third International Conference on Emerging Security Technologies.

[173]  Anton Nijholt Competing and Collaborating Brains: Multi-brain Computer Interfacing , 2015, Brain-Computer Interfaces.

[174]  R Andy McKinley,et al.  Acceleration of image analyst training with transcranial direct current stimulation. , 2013, Behavioral neuroscience.

[175]  E. Haffen,et al.  Transcranial direct current stimulation for memory enhancement: from clinical research to animal models , 2014, Front. Syst. Neurosci..

[176]  Iñaki Iturrate,et al.  Shared-control brain-computer interface for a two dimensional reaching task using EEG error-related potentials , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[177]  I. Janis,et al.  Decision Making: A Psychological Analysis of Conflict, Choice, and Commitment , 1977 .

[178]  Riccardo Poli,et al.  A collaborative Brain-Computer Interface for improving group detection of visual targets in complex natural environments , 2015, 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER).

[179]  Thibault Gateau,et al.  In silico vs. Over the Clouds: On-the-Fly Mental State Estimation of Aircraft Pilots, Using a Functional Near Infrared Spectroscopy Based Passive-BCI , 2018, Front. Hum. Neurosci..

[180]  E. Donchin,et al.  Talking off the top of your head: toward a mental prosthesis utilizing event-related brain potentials. , 1988, Electroencephalography and clinical neurophysiology.

[181]  C. Tesche,et al.  Transcranial direct current stimulation modulates shifts in global/local attention , 2009, Neuroreport.

[182]  Riccardo Poli,et al.  Augmenting group performance in target-face recognition via collaborative brain-computer interfaces for surveillance applications , 2017, 2017 8th International IEEE/EMBS Conference on Neural Engineering (NER).

[183]  Miguel Nicolelis Beyond Boundaries: The New Neuroscience of Connecting Brains with Machines---and How It Will Change Our Lives , 2011 .

[184]  Eric J. Blumberg,et al.  Enhancing multiple object tracking performance with noninvasive brain stimulation: a causal role for the anterior intraparietal sulcus , 2015, Front. Syst. Neurosci..

[185]  R Parasuraman,et al.  Detection and recognition: Concurrent processes in perception , 1982, Perception & psychophysics.

[186]  E Donchin,et al.  Brain-computer interface technology: a review of the first international meeting. , 2000, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[187]  Gytis Baranauskas,et al.  What limits the performance of current invasive brain machine interfaces? , 2014, Front. Syst. Neurosci..

[188]  Paul McCullagh,et al.  Ethical Challenges Associated with the Development and Deployment of Brain Computer Interface Technology , 2014 .

[189]  N. Logothetis,et al.  Neurophysiological investigation of the basis of the fMRI signal , 2001, Nature.

[190]  Roi Cohen Kadosh,et al.  Not all brains are created equal: the relevance of individual differences in responsiveness to transcranial electrical stimulation , 2014, Front. Syst. Neurosci..

[191]  Frank H. Guenther,et al.  Artificial speech synthesizer control by brain-computer interface , 2009, INTERSPEECH.

[192]  Camilla L. Nord,et al.  Does excitatory fronto-extracephalic tDCS lead to improved working memory performance? , 2013, F1000Research.

[193]  G. Woodman,et al.  The surprising temporal specificity of direct-current stimulation , 2015, Trends in Neurosciences.

[194]  Roy H. Hamilton,et al.  An open letter concerning do‐it‐yourself users of transcranial direct current stimulation , 2016, Annals of neurology.

[195]  Raja Parasuraman,et al.  Neuroergonomics: The Brain at Work , 2006 .

[196]  Craig K. Abbey,et al.  Neural decoding of collective wisdom with multi-brain computing , 2012, NeuroImage.

[197]  S. Knecht,et al.  Non-invasive brain stimulation improves object-location learning in the elderly , 2012, Neurobiology of Aging.

[198]  José del R. Millán,et al.  Noninvasive brain-actuated control of a mobile robot by human EEG , 2004, IEEE Transactions on Biomedical Engineering.

[199]  Michael G. Rumsey Military Selection and Classification in the United States , 2012 .

[200]  F Babiloni,et al.  Passive BCI beyond the lab: current trends and future directions , 2018, Physiological measurement.

[201]  Itzhak Fried,et al.  Deep brain stimulation for enhancement of learning and memory , 2014, NeuroImage.

[202]  G. Pfurtscheller,et al.  Motor imagery activates primary sensorimotor area in humans , 1997, Neuroscience Letters.

[203]  Wim Vanduffel,et al.  A practical application of text mining to literature on cognitive rehabilitation and enhancement through neurostimulation , 2014, Front. Syst. Neurosci..

[204]  E. Parens Is better always good? The Enhancement Project. , 1998, The Hastings Center report.

[205]  O. Carter,et al.  Transcranial direct current stimulation: five important issues we aren't discussing (but probably should be) , 2014, Front. Syst. Neurosci..

[206]  Tzyy-Ping Jung,et al.  A collaborative brain-computer interface , 2011, 2011 4th International Conference on Biomedical Engineering and Informatics (BMEI).

[207]  Jing Wang,et al.  A Brain-to-Brain Interface for Real-Time Sharing of Sensorimotor Information , 2013, Scientific Reports.

[208]  Riccardo Poli,et al.  Brain–Computer Interfaces for Detection and Localization of Targets in Aerial Images , 2017, IEEE Transactions on Biomedical Engineering.

[209]  S. Yoo,et al.  Image-Guided Transcranial Focused Ultrasound Stimulates Human Primary Somatosensory Cortex , 2015, Scientific Reports.

[210]  Motoaki Kawanabe,et al.  Decoding spatial attention by using cortical currents estimated from electroencephalography with near-infrared spectroscopy prior information , 2014, NeuroImage.

[211]  Riccardo Poli,et al.  Collaborative Brain-Computer Interface for Aiding Decision-Making , 2014, PloS one.

[212]  Rui Xu,et al.  Toward a minimally invasive brain–computer interface using a single subdural channel: A visual speller study , 2013, NeuroImage.

[213]  Riccardo Poli,et al.  A collaborative Brain-Computer Interface to improve human performance in a visual search task , 2015, 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER).

[214]  Murray R. Barrick,et al.  THE BIG FIVE PERSONALITY DIMENSIONS AND JOB PERFORMANCE: A META-ANALYSIS , 1991 .

[215]  E. Vogel,et al.  Visual working memory capacity: from psychophysics and neurobiology to individual differences , 2013, Trends in Cognitive Sciences.

[216]  A. K. Basu A Theory of Decision-Making , 1973, The Journal of Sociology & Social Welfare.

[217]  Jonas Lundberg,et al.  Situation awareness systems, states and processes: a holistic framework , 2015 .

[218]  Nitish Thakor,et al.  Brain enhancement through cognitive training: a new insight from brain connectome , 2015, Front. Syst. Neurosci..

[219]  H. Flor,et al.  A spelling device for the paralysed , 1999, Nature.

[220]  Raja Parasuraman,et al.  Neuroergonomics: Research and practice , 2003 .

[221]  Ricardo Chavarriaga,et al.  Detection of anticipatory brain potentials during car driving , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[222]  Miguel A. L. Nicolelis,et al.  Extracting Kinematic Parameters for Monkey Bipedal Walking from Cortical Neuronal Ensemble Activity , 2009, Front. Integr. Neurosci..

[223]  Y. Kim,et al.  Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory , 2008, Neuroreport.

[224]  K. Doya Modulators of decision making , 2008, Nature Neuroscience.

[225]  Xuedong Chen,et al.  Decoding human motor activity from EEG single trials for a discrete two-dimensional cursor control , 2009, Journal of neural engineering.

[226]  L. Koran,et al.  Electroconvulsive therapy. , 1996, Psychiatric services.

[227]  N. Birbaumer Breaking the silence: brain-computer interfaces (BCI) for communication and motor control. , 2006, Psychophysiology.

[228]  Robert E. Hampson,et al.  Donor/recipient enhancement of memory in rat hippocampus , 2013, Front. Syst. Neurosci..

[229]  A. Brunoni,et al.  Cognitive outcomes of TMS treatment in bipolar depression: Safety data from a randomized controlled trial. , 2018, Journal of affective disorders.

[230]  E. Garcia-Rill,et al.  Gamma Band Activity , 2015 .

[231]  M. V. Gerven,et al.  Attention modulations of posterior alpha as a control signal for two-dimensional brain–computer interfaces , 2009, Journal of Neuroscience Methods.

[232]  Raja Parasuraman,et al.  Battery powered thought: Enhancement of attention, learning, and memory in healthy adults using transcranial direct current stimulation , 2014, NeuroImage.

[233]  G K Gilbert,et al.  An open letter. , 1886, Science.

[234]  Christian Kothe,et al.  Towards passive brain–computer interfaces: applying brain–computer interface technology to human–machine systems in general , 2011, Journal of neural engineering.

[235]  M. Loeb,et al.  The Psychology of Vigilance , 1982 .

[236]  Roi Cohen Kadosh,et al.  The effect of transcranial direct current stimulation: a role for cortical excitation/inhibition balance? , 2013, Front. Hum. Neurosci..

[237]  Giulio Ruffini,et al.  Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies , 2015, Brain Stimulation.

[238]  Á. Pascual-Leone,et al.  Enhanced visual spatial attention ipsilateral to rTMS-induced 'virtual lesions' of human parietal cortex , 2001, Nature Neuroscience.

[239]  T. Hirano,et al.  Rapid Communication , 2007, Gastroenterologia Japonica.

[240]  Amit P. Mulgaonkar,et al.  A review of low-intensity focused ultrasound pulsation , 2011, Brain Stimulation.

[241]  S. Small,et al.  AN INTRODUCTION TO FUNCTIONAL MAGNETIC RESONANCE IMAGING , 1999 .

[242]  R. Ilmoniemi,et al.  Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain , 1993 .

[243]  Dennis J. McFarland,et al.  Brain–computer interfaces for communication and control , 2002, Clinical Neurophysiology.

[244]  Brendan Z. Allison,et al.  BCIs That Use Steady-State Visual Evoked Potentials or Slow Cortical Potentials , 2012 .

[245]  Raja Parasuraman,et al.  Using Noninvasive Brain Stimulation to Accelerate Learning and Enhance Human Performance , 2014, Hum. Factors.

[246]  Justin C. Sanchez,et al.  DARPA-funded efforts in the development of novel brain–computer interface technologies , 2015, Journal of Neuroscience Methods.

[247]  Max A. Viergever,et al.  Real-Time Decoding of Brain Responses to Visuospatial Attention Using 7T fMRI , 2011, PloS one.

[248]  David Tartakover,et al.  How many people? , 2007, Lancet.

[249]  M. Viergever,et al.  Real-time decoding of the direction of covert visuospatial attention. , 2012, Journal of neural engineering.

[250]  Abhishek Datta,et al.  Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: A basis for high-definition tDCS , 2013, NeuroImage.

[251]  S. Hillyard,et al.  Event-related brain potentials in the study of visual selective attention. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[252]  Paul Root Wolpe,et al.  When “I” becomes “We”: ethical implications of emerging brain-to-brain interfacing technologies , 2014, Front. Neuroeng..

[253]  Pete Moore,et al.  Enhancing Me: The Hope and the Hype of Human Enhancement , 2008 .

[254]  Tzyy-Ping Jung,et al.  A Collaborative Brain-Computer Interface for Accelerating Human Decision Making , 2013, HCI.

[255]  Stephen H. Fairclough,et al.  Editorial: Trends in Neuroergonomics , 2017, Front. Hum. Neurosci..

[256]  Elaine Astrand,et al.  Selective visual attention to drive cognitive brain–machine interfaces: from concepts to neurofeedback and rehabilitation applications , 2014, Front. Syst. Neurosci..

[257]  Michael E. Smith,et al.  Neurophysiological measures of cognitive workload during human-computer interaction , 2003 .

[258]  D. Reato,et al.  Gyri-precise head model of transcranial direct current stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad , 2009, Brain Stimulation.

[259]  Raja Parasuraman,et al.  Neuroenhancement: Enhancing brain and mind in health and in disease , 2014, NeuroImage.

[260]  Riccardo Poli,et al.  Enhancement of Group Perception via a Collaborative Brain–Computer Interface , 2017, IEEE Transactions on Biomedical Engineering.

[261]  F. Fregni,et al.  Enhancement of selective attention by tDCS: Interaction with interference in a Sternberg task , 2012, Neuroscience Letters.

[262]  Ali Bahramisharif,et al.  Brain-computer interfacing using modulations of alpha activity induced by covert shifts of attention , 2011, Journal of NeuroEngineering and Rehabilitation.

[263]  Wolfgang Rosenstiel,et al.  An MEG-based brain–computer interface (BCI) , 2007, NeuroImage.

[264]  T.W. Berger,et al.  Restoring lost cognitive function , 2005, IEEE Engineering in Medicine and Biology Magazine.

[265]  R Kakigi,et al.  [Event-related brain potentials]. , 1997, Nihon rinsho. Japanese journal of clinical medicine.

[266]  Raja Parasuraman,et al.  Wearable functional near infrared spectroscopy (fNIRS) and transcranial direct current stimulation (tDCS): expanding vistas for neurocognitive augmentation , 2015, Front. Syst. Neurosci..

[267]  Kathleen M. Carley,et al.  Workgroup Members , 2022 .

[268]  Paul Sacco,et al.  Modulation of internal model formation during force field‐induced motor learning by anodal transcranial direct current stimulation of primary motor cortex , 2009, The Journal of physiology.

[269]  Neurofeedback of Slow Cortical Potentials in Children with Attention-Deficit/Hyperactivity Disorder: A Multicenter Randomized Trial Controlling for Unspecific Effects , 2017, Front. Hum. Neurosci..

[270]  Wolfgang Grodd,et al.  Principles of a brain-computer interface (BCI) based on real-time functional magnetic resonance imaging (fMRI) , 2004, IEEE Transactions on Biomedical Engineering.

[271]  B. Oken,et al.  Vigilance, alertness, or sustained attention: physiological basis and measurement , 2006, Clinical Neurophysiology.

[272]  L. Parra,et al.  Inter-Individual Variation during Transcranial Direct Current Stimulation and Normalization of Dose Using MRI-Derived Computational Models , 2012, Front. Psychiatry.

[273]  Dae C. Shin,et al.  Facilitation of memory encoding in primate hippocampus by a neuroprosthesis that promotes task-specific neural firing , 2013, Journal of neural engineering.

[274]  Ingrid Moreno-Duarte,et al.  Transcranial Electrical Stimulation: Transcranial Direct Current Stimulation (tDCS), Transcranial Alternating Current Stimulation (tACS), Transcranial Pulsed Current Stimulation (tPCS), and Transcranial Random Noise Stimulation (tRNS) , 2014 .

[275]  A. Brunoni,et al.  Working memory improvement with non-invasive brain stimulation of the dorsolateral prefrontal cortex: A systematic review and meta-analysis , 2014, Brain and Cognition.

[276]  Á. Pascual-Leone,et al.  Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies , 2014, Brain Stimulation.

[277]  Laura Astolfi,et al.  Defecting or Not Defecting: How to “Read” Human Behavior during Cooperative Games by EEG Measurements , 2010, PloS one.

[278]  Niels Birbaumer,et al.  Insula and inferior frontal triangularis activations distinguish between conditioned brain responses using emotional sounds for basic BCI communication , 2014, Front. Behav. Neurosci..

[279]  S. Hillyard,et al.  The division of attention and the human auditory evoked potential , 1977, Neuropsychologia.

[280]  Werner Lutzenberger,et al.  BIOFEEDBACK OF EVENT‐RELATED SLOW POTENTIALS OF THE BRAIN , 1981 .

[281]  Atsuo Murata,et al.  Evaluation of mental fatigue using feature parameter extracted from event-related potential , 2002 .

[282]  N. Agar Liberal Eugenics: In Defence of Human Enhancement , 2004 .

[283]  Á. Pascual-Leone,et al.  Diminishing Risk-Taking Behavior by Modulating Activity in the Prefrontal Cortex: A Direct Current Stimulation Study , 2007, The Journal of Neuroscience.

[284]  C. Cinel,et al.  Multi-brain fusion and applications to intelligence analysis , 2013, Defense, Security, and Sensing.

[285]  T. Demiralp,et al.  What if you are not sure? Electroencephalographic correlates of subjective confidence level about a decision , 2012, Clinical Neurophysiology.

[286]  J W Hedge,et al.  Personnel selection. , 1997, Annual review of psychology.

[287]  W. H. Dobelle Artificial vision for the blind by connecting a television camera to the visual cortex. , 2000, ASAIO journal.

[288]  Dong Song,et al.  Developing a hippocampal neural prosthetic to facilitate human memory encoding and recall , 2018, Journal of neural engineering.

[289]  J. H. Hong,et al.  Gamma band activity associated with BCI performance: simultaneous MEG/EEG study , 2013, Front. Hum. Neurosci..

[290]  Marina Schmid,et al.  An Introduction To The Event Related Potential Technique , 2016 .

[291]  Hussein A. Abbass,et al.  Augmented Cognition using Real-time EEG-based Adaptive Strategies for Air Traffic Control , 2014 .

[292]  G. Pfurtscheller,et al.  Event-related cortical desynchronization detected by power measurements of scalp EEG. , 1977, Electroencephalography and clinical neurophysiology.

[293]  N. Bostrom In defense of posthuman dignity. , 2005, Bioethics.

[294]  Fabien Lotte,et al.  Brain-Computer Interfaces: Beyond Medical Applications , 2012, Computer.

[295]  Szczepan Paszkiel,et al.  Brain–Computer Interface Technology , 2019, Analysis and Classification of EEG Signals for Brain–Computer Interfaces.

[296]  Keum-Shik Hong,et al.  fNIRS-based brain-computer interfaces: a review , 2015, Front. Hum. Neurosci..

[297]  Chris Berka,et al.  Evaluation of an EEG workload model in an Aegis simulation environment , 2005, SPIE Defense + Commercial Sensing.

[298]  Gert Pfurtscheller,et al.  Brain-computer interface: a new communication device for handicapped persons , 1993 .

[299]  Ernst Fernando Lopes Da Silva Niedermeyer,et al.  Electroencephalography, basic principles, clinical applications, and related fields , 1982 .

[300]  Walter Paulus,et al.  Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human , 2004, Neuropsychologia.

[301]  Lindsey K. McIntire,et al.  Augmenting Visual Search Performance With Transcranial Direct Current Stimulation (tDCS) , 2015 .

[302]  Gary E. Birch,et al.  A brain-controlled switch for asynchronous control applications , 2000, IEEE Trans. Biomed. Eng..

[303]  Riccardo Poli,et al.  Towards the automated localisation of targets in rapid image-sifting by collaborative brain-computer interfaces , 2017, PloS one.

[304]  C. Cinel,et al.  P300-Based BCI Mouse With Genetically-Optimized Analogue Control , 2008, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[305]  C. G. Lim,et al.  Effectiveness of a brain-computer interface based programme for the treatment of ADHD: a pilot study. , 2010, Psychopharmacology bulletin.

[306]  Giulia Neri-Castracane DOES THE BUSINESS JUDGMENT RULE HELP PROMOTE CORPORATE SOCIAL RESPONSIBILITY , 2015 .

[307]  M. Hallett,et al.  Modulation of muscle responses evoked by transcranial magnetic stimulation during the acquisition of new fine motor skills. , 1995, Journal of neurophysiology.