Performing technologically advanced work in an environment hostile to human existence on a limited budget necessitates good teamwork, a phenomenon that spaceflight agencies (and countless other organizations) around the world recognize. We suggest that the National Aeronautics and Space Administration (NASA) serves as an exemplar of an organization that has recognized and attempted to respond to many of the challenges articulated by Tannenbaum, Mathieu, Salas, and Cohen (2012). In addition, we suggest that spaceflight operations of the future can serve as an information resource and operational laboratory for future research on teams and teamwork. Historically, NASA has been comprising teams that needed to work together in high criticality situations, which often involved the coordination and cooperation