Inflammatory Fibroid Polyp: An Unusual Cause of Ileoileal Intussusception

Inflammatory fibroid polyp (IFP), or Vanek's tumor, is a rare benign lesion of the gastrointestinal tract. Clinical manifestations of IFP vary based on size and location within the GI tract. This case describes a patient who presented with hematochezia and abdominal pain. Computed tomography revealed ileoileal intussusception without a clear lead point. The patient underwent resection of the intussuscepted small bowel with primary anastomosis. A large polypoid mass was identified as the pathological lead point. Histopathological and immunohistochemical analysis revealed an IFP. Review of the literature indicates that early surgical intervention is the treatment of choice for intussusception caused by IFP. Lesions are typically reported as solitary, and resection is curative.

[1]  B. Abboud Vanek's tumor of the small bowel in adults. , 2015, World journal of gastroenterology.

[2]  A. Fucic,et al.  Estrogen and androgen receptors in inflammatory fibroid polyp (Vanek's tumor): case report. , 2014, Anticancer research.

[3]  Chenghai Zhang,et al.  Massive gastrointestinal bleeding caused by a giant gastric inflammatory fibroid polyp: A case report , 2014, International journal of surgery case reports.

[4]  S. Steigen,et al.  Do Not Be Fooled by Fancy Mutations: Inflammatory Fibroid Polyps Can Harbor Mutations Similar to Those Found in GIST , 2013, Case reports in medicine.

[5]  I. Maleki,et al.  Jejunal intussusception caused by a huge Vanek's tumor: a case report , 2013, Gastroenterology and hepatology from bed to bench.

[6]  R. Shukla,et al.  Inflammatory Fibroid Polyp: A Rare Benign Tumor of the Alimentary Tract in Children Presenting As Intussusception—Case Report and Review of Literature , 2013, European Journal of Pediatric Surgery Reports.

[7]  E. Montgomery,et al.  Inflammatory Fibroid Polyps of the Gastrointestinal Tract: Spectrum of Clinical, Morphologic, and Immunohistochemistry Features , 2013, The American journal of surgical pathology.

[8]  S. Akbulut Intussusception due to inflammatory fibroid polyp: a case report and comprehensive literature review. , 2012, World journal of gastroenterology.

[9]  Ronaldo Nonose,et al.  Ileal Intussusception Caused by Vanek's Tumor: A Case Report , 2011, Case Reports in Gastroenterology.

[10]  S. Yakan,et al.  Intussusception in adults: clinical characteristics, diagnosis and operative strategies. , 2009, World journal of gastroenterology.

[11]  J. Tworek,et al.  Giant ileal inflammatory fibroid polyp causing small bowel obstruction: a case report and review of the literature , 2008, Cases journal.

[12]  E. Wardelmann,et al.  Inflammatory fibroid polyps harbour mutations in the platelet‐derived growth factor receptor alpha (PDGFRA) gene , 2008, The Journal of pathology.

[13]  K. Sugano,et al.  A case of inflammatory fibroid polyp causing small-bowel intussusception in which retrograde double-balloon enteroscopy was useful for the preoperative diagnosis. , 2004, Endoscopy.

[14]  J. Vaněk Gastric submucosal granuloma with eosinophilic infiltration. , 1949, The American journal of pathology.

[15]  K. Mönkemüller,et al.  Endoscopic characterization and resection of Vanek’s tumor of the duodenum , 2015, Endoscopy.

[16]  F. Laurent,et al.  An inflammatory fibroid polyp responsible for an ileal intussusception discovered on an MRI. , 2015, Diagnostic and interventional imaging.

[17]  J. Sola,et al.  Ileal Vanek's tumor mimicking cecal carcinoma. , 2012, Tumori.