A New Testing Strategy to Identify Rare Variants with Either Risk or Protective Effect on Disease
暂无分享,去创建一个
Iuliana Ionita-Laza | Christoph Lange | Nan M. Laird | Joseph D. Buxbaum | J. Buxbaum | N. Laird | I. Ionita-Laza | C. Lange
[1] Lee-Jen Wei,et al. Pooled Association Tests for Rare Variants in Exon-Resequencing Studies , 2010 .
[2] Judy H. Cho,et al. Finding the missing heritability of complex diseases , 2009, Nature.
[3] Bruce Winney,et al. Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[4] E. Mardis. The impact of next-generation sequencing technology on genetics. , 2008, Trends in genetics : TIG.
[5] Joshua M. Korn,et al. Association between microdeletion and microduplication at 16p11.2 and autism. , 2008, The New England journal of medicine.
[6] E. Mayr. Adaptation and selection , 1981 .
[7] S. Leal,et al. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. , 2008, American journal of human genetics.
[8] M. Metzker. Sequencing technologies — the next generation , 2010, Nature Reviews Genetics.
[9] Gonçalo R. Abecasis,et al. GENOME: a rapid coalescent-based whole genome simulator , 2007, Bioinform..
[10] M. Marra,et al. Massively parallel sequencing: the next big thing in genetic medicine. , 2009, American journal of human genetics.
[11] Jonathan C. Cohen,et al. Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[12] Shamil R Sunyaev,et al. Pooled association tests for rare variants in exon-resequencing studies. , 2010, American journal of human genetics.
[13] Hongyu Zhao,et al. Rare independent mutations in renal salt handling genes contribute to blood pressure variation , 2008, Nature Genetics.
[14] W. Bodmer,et al. Rare Variant Hypothesis for Multifactorial Inheritance: Susceptibility to Colorectal Adenomas as a Model , 2005, Cell cycle.
[15] Christian E Elger,et al. 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy , 2009, Nature Genetics.
[16] B. Maher. Personal genomes: The case of the missing heritability , 2008, Nature.
[17] E. Zeggini,et al. An Evaluation of Statistical Approaches to Rare Variant Analysis in Genetic Association Studies , 2009, Genetic epidemiology.
[18] P. Shannon,et al. Exome sequencing identifies the cause of a Mendelian disorder , 2009, Nature Genetics.
[19] P. Buckley. Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia , 2009 .
[20] Hanlee P. Ji,et al. Next-generation DNA sequencing , 2008, Nature Biotechnology.
[21] J. Pritchard,et al. The allelic architecture of human disease genes: common disease-common variant...or not? , 2002, Human molecular genetics.
[22] A. Singleton,et al. Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia , 2008, Science.
[23] S. Browning,et al. A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic , 2009, PLoS genetics.
[24] J. Pritchard. Are rare variants responsible for susceptibility to complex diseases? , 2001, American journal of human genetics.
[25] E. Lander,et al. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results , 1995, Nature Genetics.
[26] Thomas W. Mühleisen,et al. Large recurrent microdeletions associated with schizophrenia , 2008, Nature.
[27] G. Simpson,et al. Genetics, paleontology, and evolution. , 1949 .
[28] M. McCarthy,et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges , 2008, Nature Reviews Genetics.
[29] J. Todd,et al. Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes , 2009, Science.
[30] Jonathan C. Cohen,et al. Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol , 2004, Science.