Therapeutic angiogenesis inhibits or rescues chemotherapy-induced peripheral neuropathy: taxol- and thalidomide-induced injury of vasa nervorum is ameliorated by VEGF.

[1]  Y. Yoon,et al.  Antiangiogenesis Mediates Cisplatin-Induced Peripheral Neuropathy: Attenuation or Reversal by Local Vascular Endothelial Growth Factor Gene Therapy Without Augmenting Tumor Growth , 2005, Circulation.

[2]  J. Berlin,et al.  Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. , 2004, The New England journal of medicine.

[3]  J. Isner,et al.  Transcutaneous ultrasound augments naked DNA transfection of skeletal muscle. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

[4]  J. Isner,et al.  Plasma vascular endothelial growth factor (VEGF) levels after intramuscular and intramyocardial gene transfer of VEGF-1 plasmid DNA. , 2002, Human gene therapy.

[5]  G. Mills,et al.  Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models. , 2002, Cancer research.

[6]  G. Christofori,et al.  Overexpression of Vascular Endothelial Growth Factor-a165 Updated Version Cited Articles Citing Articles E-mail Alerts Overexpression of Vascular Endothelial Growth Factor-a165 Enhances Tumor Angiogenesis but Not Metastasis during ␤-cell Carcinogenesis , 2013 .

[7]  M. Floeter,et al.  Thalidomide neuropathy in patients treated for metastatic prostate cancer , 2001, Muscle & nerve.

[8]  S. Rajkumar.  Thalidomide in the treatment of multiple myeloma , 2001, Expert review of anticancer therapy.

[9]  A. Rustgi,et al.  Paclitaxel Induces Prolonged Activation of the Ras/MEK/ERK Pathway Independently of Activating the Programmed Cell Death Machinery* , 2001, The Journal of Biological Chemistry.

[10]  J. Isner,et al.  Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia. , 2001, Archives of neurology.

[11]  J. Isner,et al.  Reversal of experimental diabetic neuropathy by VEGF gene transfer. , 2001, The Journal of clinical investigation.

[12]  Stephen J. Williams,et al.  The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel. , 2000, Cancer research.

[13]  J. Alroy,et al.  Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy , 2000, Nature Medicine.

[14]  A. Zeiher,et al.  Akt takes center stage in angiogenesis signaling. , 2000, Circulation research.

[15]  G. Lundborg,et al.  Vascular endothelial growth factor stimulates Schwann cell invasion and neovascularization of acellular nerve grafts , 1999, Brain Research.

[16]  G. Lundborg,et al.  Vascular Endothelial Growth Factor Has Neurotrophic Activity and Stimulates Axonal Outgrowth, Enhancing Cell Survival and Schwann Cell Proliferation in the Peripheral Nervous System , 1999, The Journal of Neuroscience.

[17]  Y. Fujio,et al.  Akt Mediates Cytoprotection of Endothelial Cells by Vascular Endothelial Growth Factor in an Anchorage-dependent Manner* , 1999, The Journal of Biological Chemistry.

[18]  J. Isner,et al.  Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. , 1999, The American journal of pathology.

[19]  J. Isner,et al.  Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. , 1998, Circulation.

[20]  Vishva Dixit,et al.  Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway , 1998, The Journal of Biological Chemistry.

[21]  K Walsh,et al.  Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. , 1998, Circulation.

[22]  J. Isner,et al.  Arterial gene transfer of naked DNA for therapeutic angiogenesis: early clinical results. , 1998, Advanced drug delivery reviews.

[23]  P. Huang,et al.  Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. , 1998, The Journal of clinical investigation.

[24]  P. Distefano,et al.  Physiological characterization of taxol‐induced large‐fiber sensory neuropathy in the rat , 1998, Annals of neurology.

[25]  R. Saura,et al.  A mechanism of cisplatin action: antineoplastic effect through inhibition of neovascularization. , 1997, The Kobe journal of medical sciences.

[26]  J. Isner,et al.  Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion. , 1996, Circulation.

[27]  G. Viale,et al.  The microtubule-affecting drug paclitaxel has antiangiogenic activity. , 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

[28]  Takayuki Asahara,et al.  Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb , 1996, The Lancet.

[29]  K Walsh,et al.  Arterial gene transfer for therapeutic angiogenesis in patients with peripheral artery disease. , 1996, Human gene therapy.

[30]  Atsushi Namiki,et al.  Hypoxia Induces Vascular Endothelial Growth Factor in Cultured Human Endothelial Cells (*) , 1995, The Journal of Biological Chemistry.

[31]  H. Dvorak,et al.  Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. , 1995, The American journal of pathology.

[32]  G. Cavaletti,et al.  Peripheral neurotoxicity of taxol in patients previously treated with cisplatin , 1995 .

[33]  A. Harris,et al.  Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells. , 1995, Journal of the National Cancer Institute.

[34]  R. Donehower,et al.  Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies , 1994, Annals of neurology.

[35]  J. Arezzo,et al.  Nerve growth factor prevents toxic neuropathy in mice , 1991, Annals of neurology.

[36]  D. Goeddel,et al.  Vascular endothelial growth factor is a secreted angiogenic mitogen. , 1989, Science.

[37]  J. Arezzo,et al.  Rabbit sural nerve responses to chronic treatment with thalidomide and supidimide , 1984, Muscle & nerve.

[38]  J. Folkman.  Tumor angiogenesis: therapeutic implications. , 1971, The New England journal of medicine.

[39]  J. Schröder,et al.  Experimental thalidomide neuropathy: The morphological correlate of reduced conduction velocity , 2004, Acta Neuropathologica.

[40]  H. Hartung,et al.  Chemotherapy-induced peripheral neuropathy , 2002, Journal of Neurology.

[41]  R. D'Amato,et al.  Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. , 1997, Cancer research.