Celastrus orbiculatus extract suppresses gastric cancer stem cells through the TGF-β/Smad signaling pathway

[1]  Yanqing Liu,et al.  Celastrus Orbiculatus Extract Inhibits the Epithelial-mesenchymal Transition Process by Transforming Growth Factor-β Signaling Pathway in Gastric Cancer. , 2021, Anti-cancer agents in medicinal chemistry.

[2]  Yi-xue Gu,et al.  Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis , 2021, Journal of experimental & clinical cancer research : CR.

[3]  Li Tao,et al.  CD133+/CD166+ human gastric adenocarcinoma cells present the properties of neoplastic stem cells and emerge more malignant features. , 2021, Life sciences.

[4]  Yao-dong Zhu,et al.  Celastrus orbiculatus Extract Reduces Stemness of Gastric Cancer Stem Cells by Targeting PDCD4 and EIF3H , 2021, Integrative cancer therapies.

[5]  R. Derynck,et al.  TGFβ biology in cancer progression and immunotherapy , 2020, Nature Reviews Clinical Oncology.

[6]  U. Ganswindt,et al.  The Role of Cancer Stem Cells in Radiation Resistance , 2020, Frontiers in Oncology.

[7]  Ping Li,et al.  MiR-326 inhibits inflammation and promotes autophagy in silica-induced pulmonary fibrosis through targeting TNFSF14 and PTBP1. , 2019, Chemical research in toxicology.

[8]  Q. Zhang,et al.  Traditional uses, secondary metabolites, and pharmacology of Celastrus species - a review. , 2019, Journal of ethnopharmacology.

[9]  A. Samadani,et al.  Therapeutic approach of Cancer stem cells (CSCs) in gastric adenocarcinoma; DNA methyltransferases enzymes in cancer targeted therapy. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[10]  Li Tao,et al.  Cytotoxic abietane and kaurane diterpenoids from Celastrus orbiculatus , 2019, Journal of Natural Medicines.

[11]  J. Capp.  Cancer Stem Cells: From Historical Roots to a New Perspective , 2019, Journal of oncology.

[12]  Tianxin Lin,et al.  Polypyrimidine tract binding protein 1 promotes lymphatic metastasis and proliferation of bladder cancer via alternative splicing of MEIS2 and PKM. , 2019, Cancer letters.

[13]  Masahiro Shibata,et al.  Targeting Cancer Stem Cells: A Strategy for Effective Eradication of Cancer , 2019, Cancers.

[14]  M. Seno,et al.  Conversion of Stem Cells to Cancer Stem Cells: Undercurrent of Cancer Initiation , 2019, Cancers.

[15]  Ç. Biray Avcı,et al.  Cancer stem cells: A brief review of the current status. , 2019, Gene.

[16]  K. Mortezaee.  Human hepatocellular carcinoma: Protection by melatonin , 2018, Journal of cellular physiology.

[17]  M. Najafi,et al.  Adjuvant chemotherapy with melatonin for targeting human cancers: A review , 2018, Journal of cellular physiology.

[18]  K. Akashi,et al.  Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer , 2018, Oncogene.

[19]  Stephan Marquardt,et al.  Emerging functional markers for cancer stem cell-based therapies: Understanding signaling networks for targeting metastasis. , 2018, Seminars in cancer biology.

[20]  W. Shen,et al.  Senescence and Cancer , 2018, Cancer translational medicine.

[21]  Tao Li,et al.  Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα , 2018, Front. Pharmacol..

[22]  T. S. Ramasamy,et al.  Cancer stem cells as key drivers of tumour progression , 2018, Journal of Biomedical Science.

[23]  Ita Novita Sari,et al.  Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment , 2018, Stem cells international.

[24]  H. Kuang,et al.  Pharmacological Effect of Caulophyllum robustum on Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-κB, and Proinflammatory Cytokines In Vivo and In Vitro , 2017, Evidence-based complementary and alternative medicine : eCAM.

[25]  Jianguo Wu,et al.  Long noncoding RNA H19 interacts with polypyrimidine tract‐binding protein 1 to reprogram hepatic lipid homeostasis , 2017, Hepatology.

[26]  H. Clevers,et al.  Cancer stem cells revisited , 2017, Nature Medicine.

[27]  Yayun Qian,et al.  Anticancer efficacy of the ethyl acetate extract from the traditional Chinese medicine herb Celastrus orbiculatus against human gastric cancer. , 2017, Journal of ethnopharmacology.

[28]  X. Q. Wang,et al.  Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells , 2017, Oncotarget.

[29]  H. Xi,et al.  A unified model of the hierarchical and stochastic theories of gastric cancer , 2017, British Journal of Cancer.

[30]  Yayun Qian,et al.  Celastrus orbiculatus extract inhibits the migration and invasion of human glioblastoma cells in vitro , 2016, BMC Complementary and Alternative Medicine.

[31]  R. Palmqvist,et al.  SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer , 2016, BMC Cancer.

[32]  Bao-Xin Li,et al.  TGF-β1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells , 2016, Tumor Biology.

[33]  P. Korošec,et al.  BMI1, ALDH1A1, and CD133 Transcripts Connect Epithelial-Mesenchymal Transition to Cancer Stem Cells in Lung Carcinoma , 2015, Stem cells international.

[34]  Panagiota Arampatzi,et al.  Common stemness regulators of embryonic and cancer stem cells. , 2015, World journal of stem cells.

[35]  Michael Kahn,et al.  Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update , 2015, Nature Reviews Clinical Oncology.

[36]  Jason G. Jin,et al.  Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes , 2015, Nature Medicine.

[37]  Steven J. M. Jones,et al.  Comprehensive molecular characterization of gastric adenocarcinoma , 2014, Nature.

[38]  Zhong Li,et al.  CD133: a stem cell biomarker and beyond , 2013, Experimental Hematology & Oncology.

[39]  S. Lipkin,et al.  Asymmetric division: a marker for cancer stem cells? , 2013, Oncotarget.

[40]  T. Efferth.  Stem Cells, Cancer Stem-Like Cells, and Natural Products , 2012, Planta Medica.

[41]  Peter Dirks,et al.  Cancer stem cells: an evolving concept , 2012, Nature Reviews Cancer.

[42]  Karnail Singh,et al.  Polypyrimidine Tract-Binding Protein Is Critical for the Turnover and Subcellular Distribution of CD40 Ligand mRNA in CD4+ T Cells , 2011, The Journal of Immunology.

[43]  M. Henderson,et al.  CANCER STEM CELLS: A REVIEW , 2007, ANZ journal of surgery.

[44]  I. Weissman,et al.  Stem cells, cancer, and cancer stem cells , 2001, Nature.

[45]  Peter W. J. Rigby,et al.  A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo , 1990, Nature.

[46]  Y. Lee,et al.  miR-106b modulates cancer stem cell characteristics through TGF-β/Smad signaling in CD44-positive gastric cancer cells , 2014, Laboratory Investigation.