Alcohol-induced metabolomic differences in humans

[1]  Fabian J Theis,et al.  Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study , 2013, BMC Medicine.

[2]  Alireza Moayyeri,et al.  COHORT PROFILE Cohort Profile : TwinsUK and Healthy Ageing Twin Study , 2013 .

[3]  W. R. Wikoff,et al.  Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo , 2013, Translational Psychiatry.

[4]  C. Gieger,et al.  Human serum metabolic profiles are age dependent , 2012, Aging cell.

[5]  Christian Gieger,et al.  Novel biomarkers for pre-diabetes identified by metabolomics , 2012, Molecular systems biology.

[6]  D. Rujescu,et al.  Schizophrenia shows a unique metabolomics signature in plasma , 2012, Translational Psychiatry.

[7]  Fabian J Theis,et al.  Body Fat Free Mass Is Associated with the Serum Metabolite Profile in a Population-Based Study , 2012, PloS one.

[8]  Fabian J Theis,et al.  The dynamic range of the human metabolome revealed by challenges , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[9]  K. Suhre,et al.  Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics , 2012, Metabolomics.

[10]  Stef van Buuren,et al.  MICE: Multivariate Imputation by Chained Equations in R , 2011 .

[11]  H. Soininen,et al.  Metabolome in progression to Alzheimer's disease , 2011, Translational Psychiatry.

[12]  S. Ferrara,et al.  Quantitative profiling of phosphatidylethanol molecular species in human blood by liquid chromatography high resolution mass spectrometry. , 2011, Journal of chromatography. A.

[13]  C. Gieger,et al.  Human metabolic individuality in biomedical and pharmaceutical research , 2011, Nature.

[14]  W. Rathmann,et al.  Association between Markers of Fatty Liver Disease and Impaired Glucose Regulation in Men and Women from the General Population: The KORA-F4-Study , 2011, PloS one.

[15]  Fabian J Theis,et al.  Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers , 2011, PLoS genetics.

[16]  Florian Kronenberg,et al.  Differences between Human Plasma and Serum Metabolite Profiles , 2011, PloS one.

[17]  Yuqin Wang,et al.  Targeted metabolomics for biomarker discovery. , 2010, Angewandte Chemie.

[18]  Guangju Zhai,et al.  Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis , 2010, Annals of the rheumatic diseases.

[19]  Christian Gieger,et al.  A genome-wide perspective of genetic variation in human metabolism , 2010, Nature Genetics.

[20]  N. Wareham,et al.  Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study , 2010, Journal of Lipid Research.

[21]  P. Miller,et al.  Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. , 2009, Alcohol and alcoholism.

[22]  Yufang Zheng,et al.  Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS. , 2009, Clinical chemistry.

[23]  Y. Hannun,et al.  Roles and regulation of secretory and lysosomal acid sphingomyelinase. , 2009, Cellular signalling.

[24]  Christian Gieger,et al.  Metabolic Profiling Reveals Distinct Variations Linked to Nicotine Consumption in Humans — First Results from the KORA Study , 2008, PloS one.

[25]  V. Yurkiv,et al.  Effects of Ethanol and Lipopolysaccharide on the Sphingomyelin Cycle in Rat Hepatocytes , 2008, Bulletin of Experimental Biology and Medicine.

[26]  K. Kamata,et al.  Role of lysophosphatidylcholine (LPC) in atherosclerosis. , 2007, Current medicinal chemistry.

[27]  D. Peake,et al.  Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization. , 2007, Biochimica et biophysica acta.

[28]  K. Krishnan,et al.  Metabolomic mapping of atypical antipsychotic effects in schizophrenia , 2007, Molecular Psychiatry.

[29]  A. Cederbaum,et al.  Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity. , 2006, Free radical biology & medicine.

[30]  R Holle,et al.  KORA - A Research Platform for Population Based Health Research , 2005, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

[31]  C. Meisinger,et al.  The MONICA Augsburg surveys--basis for prospective cohort studies. , 2005, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

[32]  T. Cooper,et al.  Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons. , 2005, Alcoholism, clinical and experimental research.

[33]  C. Gieger,et al.  KORA-gen - Resource for Population Genetics, Controls and a Broad Spectrum of Disease Phenotypes , 2005 .

[34]  M. Laposata,et al.  Effects of alcohol on hemostasis. , 2005, American journal of clinical pathology.

[35]  B. Thorand,et al.  Food and Nutrient Intake, Anthropometric Measurements and Smoking according to Alcohol Consumption in the EPIC Heidelberg Study , 2005, Annals of Nutrition and Metabolism.

[36]  S. Rosalki.  Carbohydrate‐deficient transferrin: a marker of alcohol abuse , 2004, International journal of clinical practice.

[37]  J. Renau‐Piqueras,et al.  Ceramide pathways modulate ethanol‐induced cell death in astrocytes , 2003, Journal of neurochemistry.

[38]  S. Yokoyama,et al.  Plasma concentrations of LPL and LCAT are in putative association with females and alcohol use which are independent negative risk factors for coronary atherosclerosis among Japanese. , 2003, Clinica chimica acta; international journal of clinical chemistry.

[39]  Eric R. Ziegel,et al.  Generalized Linear Models , 2002, Technometrics.

[40]  Baofeng Yang,et al.  Phospholipid Metabolite 1-Palmitoyl-Lysophosphatidylcholine Enhances Human Ether-a-Go-Go-Related Gene (HERG) K+ Channel Function , 2001, Circulation.

[41]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[42]  F. Clavel-Chapelon,et al.  Do eating habits differ according to alcohol consumption? Results of a study of the French cohort of the European Prospective Investigation into Cancer and Nutrition (E3N-EPIC). , 2001, The American journal of clinical nutrition.

[43]  N. Nagan,et al.  Plasmalogens: biosynthesis and functions. , 2001, Progress in lipid research.

[44]  M. Laposata,et al.  Fatty acid ethyl esters in liver and adipose tissues as postmortem markers for ethanol intake. , 2001, Clinical chemistry.

[45]  G. Macfarlane,et al.  Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles , 2001, Gut.

[46]  A. Nilsson,et al.  Activation of neutral sphingomyelinase participates in ethanol-induced apoptosis in Hep G2 cells. , 2000, Alcohol and alcoholism.

[47]  C. McClain,et al.  Apoptosis and dysregulated ceramide metabolism in a murine model of alcohol-enhanced lipopolysaccharide hepatotoxicity. , 2000, Alcoholism, clinical and experimental research.

[48]  S. Shapiro,et al.  The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption , 1999, American Journal of Gastroenterology.

[49]  A. Wolk,et al.  Evaluation of a biological marker of dairy fat intake. , 1998, The American journal of clinical nutrition.

[50]  F. Snyder,et al.  Platelet-activating factor: the biosynthetic and catabolic enzymes. , 1995, The Biochemical journal.

[51]  Z. Wu,et al.  Synthesis and biohydrogenation of fatty acids by ruminal microorganisms in vitro. , 1991, Journal of dairy science.

[52]  K. J. Barry,et al.  Synthesis of phosphatidylethanol--a potential marker for adult males at risk for alcoholism. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[53]  M. Hillbom,et al.  Platelet thromboxane formation capacity after ethanol withdrawal in chronic alcoholics. , 1988, Haemostasis.

[54]  J. Kanfer,et al.  Phosphatidylethanol Formation via Transphosphatidylation by Rat Brain Synaptosomal Phospholipase D , 1987, Journal of neurochemistry.

[55]  L. Gustavsson,et al.  Formation of phosphatidylethanol in rat brain by phospholipase D. , 1987, Biochemical and biophysical research communications.

[56]  D. Mikhailidis,et al.  Platelet function defects in chronic alcoholism. , 1986, British medical journal.

[57]  J. Royston.  An Extension of Shapiro and Wilk's W Test for Normality to Large Samples , 1982 .

[58]  H. Weltzien.  Cytolytic and membrane-perturbing properties of lysophosphatidylcholine. , 1979, Biochimica et biophysica acta.

[59]  D. Bauer.  Constructing Confidence Sets Using Rank Statistics , 1972 .

[60]  J. Kornhuber,et al.  Increased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence. , 2010, Alcoholism, clinical and experimental research.

[61]  Y Wang,et al.  Targeted metabolomics and mass spectrometry. , 2010, Advances in protein chemistry and structural biology.

[62]  Peter Filzmoser,et al.  Outlier identification in high dimensions , 2008, Comput. Stat. Data Anal..

[63]  O. Fiehn.  Metabolomics – the link between genotypes and phenotypes , 2004, Plant Molecular Biology.

[64]  Katja Jachau,et al.  Concentration of fatty acid ethyl esters in hair of alcoholics: comparison to other biological state markers and self reported-ethanol intake. , 2004, Alcohol and alcoholism.

[65]  Karen Peterson,et al.  Biomarkers for Alcohol Use and Abuse , 2004, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

[66]  M. Lagarde,et al.  Characterization of plasma unsaturated lysophosphatidylcholines in human and rat. , 2000, The Biochemical journal.

[67]  L. Berglund,et al.  Pentadecanoic acid in serum as a marker for intake of milk fat: relations between intake of milk fat and metabolic risk factors. , 1999, The American journal of clinical nutrition.

[68]  L. Beilin,et al.  The effects of alcohol on coagulation and fibrinolytic factors: a controlled trial. , 1998, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

[69]  T. Hastie,et al.  Statistical Models in S , 1991 .