论文信息 - Toxicokinetics in Risk Evaluations

Toxicokinetics in Risk Evaluations

Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen.

Ans Punt | A. Punt

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[3] Ans Punt,et al. Non-animal approaches for toxicokinetics in risk evaluations of food chemicals. , 2017, ALTEX.

[4] Masoud Jamei,et al. Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory Acceptance , 2016, Current Pharmacology Reports.