Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects
暂无分享,去创建一个
E. Wagner | R. Eferl | L. Kenner | F. Karreth | P. Angel | M. Amling | M. Schorpp-Kistner | A. Hoebertz | H. Scheuch | Agnieszka P Szremska | N. Keon | Timo Beil | Marina Schorpp-Kistner
[1] W. Reith,et al. Conditional gene targeting in macrophages and granulocytes using LysMcre mice , 1999, Transgenic Research.
[2] P. Angel,et al. Defective endochondral ossification in mice with strongly compromised expression of JunB , 2003, Journal of Cell Science.
[3] E. Wagner,et al. AP-1: a double-edged sword in tumorigenesis , 2003, Nature Reviews Cancer.
[4] E. Wagner,et al. Impaired intervertebral disc formation in the absence of Jun , 2003, Development.
[5] Hiroshi Takayanagi,et al. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. , 2002, Developmental cell.
[6] E. Wagner,et al. JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms , 2002, Journal of Cell Science.
[7] A. Kolbus,et al. Cell Cycle Promoting Activity of JunB through Cyclin A Activation* , 2002, The Journal of Biological Chemistry.
[8] M. Karin,et al. AP-1 as a regulator of cell life and death , 2002, Nature Cell Biology.
[9] E. Wagner,et al. Reaching a genetic and molecular understanding of skeletal development. , 2002, Developmental cell.
[10] E. Wagner,et al. JunB can substitute for Jun in mouse development and cell proliferation , 2002, Nature Genetics.
[11] P. Plinkert,et al. The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation. , 2001, Experimental cell research.
[12] N. Kanatani,et al. Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures , 2001, The Journal of cell biology.
[13] R. Baron,et al. Carbonic anhydrase II is an AP‐1 target gene in osteoclasts , 2001, Journal of cellular physiology.
[14] E. Wagner,et al. AP-1 in mouse development and tumorigenesis , 2001, Oncogene.
[15] E. Wagner,et al. Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage , 2001, Cell.
[16] R. Baron,et al. Progressive increase in bone mass and development of odontomas in aging osteopetrotic c-src-deficient mice. , 2000, Bone.
[17] E. Wagner,et al. Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 , 2000, Nature Medicine.
[18] M. Kelz,et al. Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis , 2000, Nature Medicine.
[19] M. Wani,et al. A role for TGFbeta(1) in osteoclast differentiation and survival. , 2000, Journal of cell science.
[20] E. Wagner,et al. JunB suppresses cell proliferation by transcriptional activation of p16INK4a expression , 2000, The EMBO journal.
[21] E. Bossy‐Wetzel,et al. Cell cycle‐dependent variations in c‐Jun and JunB phosphorylation: a role in the control of cyclin D1 expression , 2000, The EMBO journal.
[22] Philippe Soriano,et al. Epiblast‐restricted Cre expression in MORE mice: A tool to distinguish embryonic vs. extra‐embryonic gene function , 2000, Genesis.
[23] E. Wagner,et al. Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation , 2000, Nature Genetics.
[24] J. Weitzman,et al. Targeted disruption of the murine junD gene results in multiple defects in male reproductive function. , 2000, Development.
[25] J. Aubin,et al. Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro , 1999, Journal of cellular biochemistry.
[26] Frank Hilberg,et al. Functions of c-Jun in Liver and Heart Development , 1999, The Journal of cell biology.
[27] G. Karsenty,et al. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. , 1999, Genes & development.
[28] E. Wagner,et al. JunB is essential for mammalian placentation , 1999, The EMBO journal.
[29] A. Lassar,et al. Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling. , 1999, Genes & development.
[30] R. Johnson,et al. c‐Jun regulates cell cycle progression and apoptosis by distinct mechanisms , 1999, The EMBO journal.
[31] R. Baron,et al. Printed in U.S.A. Copyright © 1999 by The Endocrine Society Rescue of the Skeletal Phenotype of Vitamin D Receptor- Ablated Mice in the Setting of Normal Mineral Ion , 2022 .
[32] B. Frenkel,et al. AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation. , 1999, Endocrinology.
[33] R. Baron,et al. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[34] Makoto Sato,et al. Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts , 1997, Cell.
[35] G. Karsenty,et al. Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation , 1997, Cell.
[36] L. Freedman,et al. AP-1 regulation of the rat bone sialoprotein gene transcription is mediated through a TPA response element within a glucocorticoid response unit in the gene promoter. , 1996, Matrix biology : journal of the International Society for Matrix Biology.
[37] E. Wagner,et al. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. , 1996, Nucleic acids research.
[38] G. Stein,et al. Selective expression of fos- and jun-related genes during osteoblast proliferation and differentiation. , 1995, Experimental cell research.
[39] E. Wagner,et al. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. , 1994, Science.
[40] E. Wagner,et al. Osteoblasts are target cells for transformation in c-fos transgenic mice , 1993, The Journal of cell biology.
[41] M. Karin,et al. Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun , 1989, Cell.
[42] M. Drezner,et al. Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee , 1987, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[43] M. Wani,et al. A role for TGF β 1 in osteoclast differentiation and survival , 2022 .