Improving retrospective sorting of 4D computed tomography data.

Respiratory correlated CT is commercially available, and we have implemented its routine clinical use in planning lung tumor patients. Its value is determined by the fidelity of the spatiotemporal data set after processing the acquired reconstructed slices. Retrospective sorting of reconstructed slices is based on respiratory phase. However, the existing commercial software inadequately models respiratory phase for about 30% of the patients, mainly due to irregularities in the respiratory cycle. We have developed software that improves phase determination and consequently leads to an improvement of retrospective data sorting to make 4DCT data acquisition feasible for routine clinical use. Peak inhalation and exhalation respiratory states are selected manually; intermediate phases are interpolated. Residual motion artifacts in the resulting 4DCT volumes are reduced and allow use of the 4D imaging studies for treatment planning.

[1]  Tinsu Pan,et al.  Four-dimensional computed tomography: image formation and clinical protocol. , 2005, Medical physics.

[2]  R. Mohan,et al.  Acquiring a four-dimensional computed tomography dataset using an external respiratory signal. , 2003, Physics in medicine and biology.

[3]  H Shirato,et al.  Impact of respiratory movement on the computed tomographic images of small lung tumors in three-dimensional (3D) radiotherapy. , 2000, International journal of radiation oncology, biology, physics.

[4]  T. Pan,et al.  4D-CT imaging of a volume influenced by respiratory motion on multi-slice CT. , 2004, Medical physics.

[5]  George T. Y. Chen,et al.  Artifacts in computed tomography scanning of moving objects. , 2004, Seminars in radiation oncology.

[6]  C H McCollough,et al.  Motion artifacts in subsecond conventional CT and electron-beam CT: pictorial demonstration of temporal resolution. , 2000, Radiographics : a review publication of the Radiological Society of North America, Inc.

[7]  George T. Y. Chen,et al.  Four-dimensional image-based treatment planning: Target volume segmentation and dose calculation in the presence of respiratory motion. , 2005, International journal of radiation oncology, biology, physics.

[8]  T. Guerrero,et al.  Acquiring 4D thoracic CT scans using a multislice helical method. , 2004, Physics in medicine and biology.

[9]  C. Ling,et al.  Respiration-correlated spiral CT: a method of measuring respiratory-induced anatomic motion for radiation treatment planning. , 2002, Medical physics.

[10]  T. Pan Comparison of helical and cine acquisitions for 4D-CT imaging with multislice CT. , 2005, Medical physics.

[11]  K. Lam,et al.  Uncertainties in CT-based radiation therapy treatment planning associated with patient breathing. , 1996, International journal of radiation oncology, biology, physics.

[12]  G. Christensen,et al.  A method for the reconstruction of four-dimensional synchronized CT scans acquired during free breathing. , 2003, Medical physics.