Occurrence of Candida Species Colonization in a Population of Denture-Wearing Immigrants

Infection of the oral cavity and dentures by Candida species are frequent in denture wearers. C. albicans is the most common pathogen; however, other emerging Candida species are also responsible for this condition. Few data are available about the occurrence of Candida species in the oral cavities of denture-wearing immigrants to Italy. In this study, we compare the Candida species found in the oral mucosa and on dentures from a population of denture wearing immigrants to Italy to a matched Italian group. Oral swabs were collected from dentures and the underlying mucosa of patients enrolled in the study and were then cultured to test for the presence of Candida species in each sample. Out of 168 patients enrolled (73 Italians and 95 immigrants), 51 Italians (69.8%) and 75 immigrants (78.9%) tested positive for the presence of Candida. Candida albicans was the most frequently observed species overall; however, we found a higher occurrence of C. glabrata among immigrants than among Italians. In addition, immigrants displayed a higher incidence of Candida – associated stomatitis and a lower mean age than Candida-positive individuals from the Italian group. Immigrants are more prone to longer colonization of the oral mucosa and dentures by Candida. In these patients, dentures must be checked periodically to prevent the presence of Candida.

[1]  K. Zomorodian,et al.  Determination of Antifungal Susceptibility Patterns Among the Clinical Isolates of Candida Species , 2011, Journal of global infectious diseases.

[2]  G. Quindós,et al.  In Vitro Activities of New Triazole Antifungal Agents, Posaconazole and Voriconazole, Against Oral Candida Isolates from Patients Suffering from Denture Stomatitis , 2011, Mycopathologia.

[3]  Z. Loewy,et al.  Epidemiology and etiology of denture stomatitis. , 2011, Journal of prosthodontics : official journal of the American College of Prosthodontists.

[4]  D. Bandyopadhyay,et al.  Oral health knowledge and behavior among adults with diabetes. , 2009, Diabetes research and clinical practice.

[5]  F. Çağlayan,et al.  Differential diagnosis of denture‐induced stomatitis, Candida, and their variations in patients using complete denture: a clinical and mycological study , 2009, Mycoses.

[6]  G. Quindós,et al.  Isolation of Candida dubliniensis in denture stomatitis. , 2009, Archives of oral biology.

[7]  S. Kuştımur,et al.  Surface roughness and adherence of Candida albicans on soft lining materials as influenced by accelerated aging. , 2007, The journal of contemporary dental practice.

[8]  Gordon Ramage,et al.  Candida biofilms on implanted biomaterials: a clinically significant problem. , 2006, FEMS yeast research.

[9]  E. Mierzwińska-Nastalska,et al.  Candida-associated denture stomatitis in patients after immunosuppression therapy. , 2006, Transplantation proceedings.

[10]  G. Moran,et al.  Candida dubliniensis: ten years on. , 2005, FEMS microbiology letters.

[11]  M. Ghannoum,et al.  Human Beta-defensins: Differential Activity against Candidal Species and Regulation by Candida albicans , 2005, Journal of dental research.

[12]  P. Bories,et al.  Oral candidiasis and nutritional deficiencies in elderly hospitalised patients , 2004, British Journal of Nutrition.

[13]  B. Wickes,et al.  Denture stomatitis: a role for Candida biofilms. , 2004, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[14]  A. Shehabi,et al.  Oral Candidosis in patients with removable dentures , 2003, Mycoses.

[15]  D. Coleman,et al.  Casein Agar: a Useful Medium for Differentiating Candida dubliniensis from Candida albicans , 2003, Journal of Clinical Microbiology.

[16]  E. Kazazoğlu,et al.  Oral hygiene habits, denture cleanliness, presence of yeasts and stomatitis in elderly people. , 2002, Journal of oral rehabilitation.

[17]  S. Redding.  The role of yeasts other than Candida albicans in oropharyngeal candidiasis , 2001, Current opinion in infectious diseases.

[18]  L. Samaranayake,et al.  Candida Species Exhibit Differential In Vitro Hemolytic Activities , 2001, Journal of Clinical Microbiology.

[19]  C. W. Bailey,et al.  Epidemiology of Oropharyngeal CandidaColonization and Infection in Patients Receiving Radiation for Head and Neck Cancer , 1999, Journal of Clinical Microbiology.

[20]  S. Donnelly,et al.  Phylogenetic analysis and rapid identification of Candida dubliniensis based on analysis of ACT1 intron and exon sequences. , 1999, Microbiology.

[21]  D. Soll,et al.  Natural Defenses against Candida Colonization Breakdown in the Oral Cavities of the Elderly , 1999, Journal of dental research.

[22]  J. Sobel,et al.  Candida glabrata: Review of Epidemiology, Pathogenesis, and Clinical Disease with Comparison toC. albicans , 1999, Clinical Microbiology Reviews.

[23]  C. W. Bailey,et al.  Epidemiology of Oropharyngeal CandidaColonization and Infection in Patients Receiving Radiation for Head and Neck Cancer , 1999, Journal of Clinical Microbiology.

[24]  S. Landahl,et al.  The prevalence of Staphylococcus aureus, Enterobacteriaceae species, and Candida species and their relation to oral mucosal lesions in a group of 79-year-olds in Göteborg. , 1995, Acta odontologica Scandinavica.

[25]  L. Samaranayake,et al.  Oral candidosis in the elderly in long term hospital care. , 1991, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[26]  E. Budtz-Jørgensen,et al.  Oral mucosal lesions associated with the wearing of removable dentures. , 1981, Journal of oral pathology.

[27]  E. Budtz-Jørgensen,et al.  Denture stomatitis. I. The etiology in relation to trauma and infection. , 1970, Acta odontologica Scandinavica.