Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events
暂无分享,去创建一个
Víctor M. Pérez-García | Manuel Doblaré | Jorge Santolaria | Alicia Martínez-González | Javier Berganzo | Rosa Monge | Luis J. Fernández | Ignacio Ochoa | Jeremy N. Rich | Aurelio Hernández-Laín | M. Doblaré | V. Pérez-García | J. Santolaria | J. Rich | J. Berganzo | A. Martínez-González | J. Ayuso | R. Monge | M. Virumbrales-Muñoz | G. Llamazares | A. Hernández-Laín | C. Hubert | P. Sánchez-Gómez | I. Ochoa | L. Fernández | Jose M. Ayuso | María Virumbrales-Muñoz | Pilar Sánchez-Gómez | Guillermo A. Llamazares | Christopher Hubert | L. J. Fernández | I. Ochoa
[1] Stephen J. Weiss,et al. Regulation of Cell Invasion and Morphogenesis in a Three-Dimensional Type I Collagen Matrix by Membrane-Type Matrix Metalloproteinases 1, 2, and 3 , 2000, The Journal of cell biology.
[2] Daniel J Brat,et al. 'Pseudopalisading' Necrosis in Glioblastoma: A Familiar Morphologic Feature That Links Vascular Pathology, Hypoxia, and Angiogenesis , 2006, Journal of neuropathology and experimental neurology.
[3] Rosa Villa,et al. SU-8 based microprobes for simultaneous neural depth recording and drug delivery in the brain. , 2013, Lab on a chip.
[4] Yoshiyuki Suzuki,et al. Radiotherapy plus Concomitant Adjuvant Temozolomide for Glioblastoma: Japanese Mono-Institutional Results , 2013, PloS one.
[5] J. Myung,et al. Snail plays an oncogenic role in glioblastoma by promoting epithelial mesenchymal transition. , 2014, International journal of clinical and experimental pathology.
[6] Víctor M. Pérez-García,et al. Hypoxic Cell Waves Around Necrotic Cores in Glioblastoma: A Biomathematical Model and Its Therapeutic Implications , 2012, Bulletin of Mathematical Biology.
[7] Daniel J Brat,et al. Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma , 2004, Laboratory Investigation.
[8] J. D. de Groot,et al. Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition , 2013, Clinical Cancer Research.
[9] A. Gregory Sorensen,et al. Angiogenesis in brain tumours , 2007, Nature Reviews Neuroscience.
[10] G. Gabriel,et al. SU-8 based microprobes with integrated planar electrodes for enhanced neural depth recording. , 2012, Biosensors & bioelectronics.
[11] G. Minniti,et al. Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results. , 2012, Anticancer research.
[12] Roger D Kamm,et al. Sprouting angiogenesis under a chemical gradient regulated by interactions with an endothelial monolayer in a microfluidic platform. , 2011, Analytical chemistry.
[13] Gerhard Christofori,et al. Distinct mechanisms of tumor invasion and metastasis. , 2007, Trends in molecular medicine.
[14] M. Doblaré,et al. SU-8 Based Microdevices to Study Self-Induced Chemotaxis in 3D Microenvironments , 2015, Front. Mater..
[15] N. Cordes,et al. Invasion as target for therapy of glioblastoma multiforme. , 2013, Biochimica et biophysica acta.
[16] Han-dong Wang,et al. FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway , 2014, Tumor Biology.
[17] K. Rottner,et al. Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration. , 2006, Neuron glia biology.
[18] Pallavi Sontakke,et al. Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis. , 2015, Cancer letters.
[19] Roger D Kamm,et al. A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs. , 2014, Lab on a chip.
[20] Daniel J Brat,et al. Pseudopalisades in Glioblastoma Are Hypoxic, Express Extracellular Matrix Proteases, and Are Formed by an Actively Migrating Cell Population , 2004, Cancer Research.
[21] N. Pavlidis,et al. Prognostic factors in glioblastoma patients managed with radiotherapy combined with temozolomide. , 2014, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
[22] G. F. Calvo,et al. Combined therapies of antithrombotics and antioxidants delay in silico brain tumour progression. , 2014, Mathematical medicine and biology : a journal of the IMA.
[23] D. Ba Santa,et al. 'Go or Grow': the key to the emergence of invasion in tumour progression? , 2010 .
[24] D. Brat,et al. Anti-Invasive Adjuvant Therapy with Imipramine Blue Enhances Chemotherapeutic Efficacy Against Glioma , 2012, Science Translational Medicine.
[25] J. Lennerz,et al. Neuropathology for the neuroradiologist: palisades and pseudopalisades. , 2006, AJNR. American journal of neuroradiology.
[26] D. Ingber,et al. Microfluidic organs-on-chips , 2014, Nature Biotechnology.
[27] H. H. Andersen,et al. A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion , 2012, Molecular Neurobiology.
[28] R. Jensen,et al. Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target , 2009, Journal of Neuro-Oncology.
[29] R. Kiss,et al. Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[30] M. Tijero,et al. Novel three-dimensional embedded SU-8 microchannels fabricated using a low temperature full wafer adhesive bonding , 2004 .
[31] Roger D Kamm,et al. A high-throughput microfluidic assay to study neurite response to growth factor gradients. , 2011, Lab on a chip.
[32] S. Hayashi,et al. The role of proteolysis in tumor invasiveness in glioblastoma and metastatic brain tumors. , 2002, Anticancer research.
[33] Erwin G. Van Meir,et al. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. , 2005, Cancer research.
[34] Daniel J Brat,et al. Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors. , 2003, Frontiers in bioscience : a journal and virtual library.
[35] P. Friedl. Prespecification and plasticity: shifting mechanisms of cell migration. , 2004, Current opinion in cell biology.