Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis

•  Introduction •  Insulin, IGF‐1 in the brain •  Glucose metabolism and AD •  The insulin and IGF‐1 system in AD •  The insulin and oxidative stress in AD •  The insulin and IGF‐1R system and τ phosphorylation •  Brain amyloid and insulin IGF‐1 signalling •  Insulin, inflammation and AD •  Conclusions

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