Introduction: Advent of new technologies in mobile devices and software applications is leading to an evolving change in the extent, geographies and modes for use of internet. Today, it is used not only for information gathering but for sharing of experiences, opinions and suggestions. Web-Recognizing Adverse Drug Reactions (RADR) is a groundbreaking European Union (EU) Innovative Medicines Innovation funded 3-year initiative to recommend policies, frameworks, tools and methodologies by leveraging these new developments to get new insights in drug safety. Areas covered: Data were gathered from prior surveys, previous initiatives and a review of relevant literature was done. New technologies provide an opportunity in the way safety information is collected, helping generate new knowledge for safety profile of drugs as well as unique insights into the evolving pharmacovigilance system in general. It is critical that these capabilities are harnessed in a way that is ethical, compliant with regulations, respecting data privacy and used responsibly. At the same time, the process for managing and interpreting this new information must be efficient and effective for sustenance, thoughtful use of resources and valuable return of knowledge. These approaches should complement the ongoing progress toward personalized medicine. Expert opinion: This Web-RADR initiative should provide some directions on ‘what and how’ to use social media to further proactive pharmacovigilance and protection of public health. It is expected to also show how a multipronged expert consortium group comprising regulators, industry and academia can leverage new developments in technology and society to bring innovation in process, operations, organization and scientific approaches across its boundaries and beyond the normal realms of individual research units. These new approaches should bring insights faster, earlier, specific, actionable and moving toward the target of AE prevention. The possibilities of a blended targeted pharmacovigilance (PV) approach where boundaries between stakeholders blur and cultures mix point to very different future for better, healthier and longer lives.
[1]
L. Hazell,et al.
Under-Reporting of Adverse Drug Reactions
,
2006,
Drug safety.
[2]
D. Classen,et al.
'Global trigger tool' shows that adverse events in hospitals may be ten times greater than previously measured.
,
2011,
Health affairs.
[3]
C M Bond,et al.
Evaluation of patient reporting of adverse drug reactions to the UK 'Yellow Card Scheme': literature review, descriptive and qualitative analyses, and questionnaire surveys.
,
2011,
Health technology assessment.
[4]
Martin L. Hammond.
Moore's law: The first 70 years
,
2004
.
[5]
Samuel J. Davey,et al.
A Comparison of Detection Performance for Several Track-before-Detect Algorithms
,
2008,
2008 11th International Conference on Information Fusion.
[6]
Kaveh G Shojania,et al.
Trends in adverse events over time: why are we not improving?
,
2013,
BMJ quality & safety.
[7]
Jun Du,et al.
The innovation value chain
,
2006
.
[8]
Cordula Wagner,et al.
Changes in adverse event rates in hospitals over time: a longitudinal retrospective patient record review study
,
2013,
BMJ quality & safety.
[9]
C Wagner,et al.
Adverse events and potentially preventable deaths in Dutch hospitals: results of a retrospective patient record review study
,
2002,
Quality & Safety in Health Care.