Antimicrobial nanotechnology: research implications and prospects in food safety

A review of the applications of antimicrobial nanomaterials and nanotechnology in improving various aspects of food safety and preservation is presented in this chapter. The review first summarizes the antimicrobial activity of a number of metallic and inorganic nanoparticles with the mechanism of action and factors affecting antimicrobial activity of the nanoparticles. Initially, an overview is presented of the applications of the nano-antimicrobials in active food packaging systems for preserving foods and for enhancing microbial safety of foods. The recent trend of using nano-based sensors in intelligent packaging systems for detection of microbial contaminants in foods, and the efficacy of nanocomposites in the prevention of biofilm formation and biofouling in food industry is also discussed. Acceptance of this novel technology in various aspects of food preservation and safety requires further studies to establish absence of adverse effects of nano-materials and their safe use on foods and food contact surfaces.

[1]  F. Medellín-Rodríguez,et al.  Mechanical and Antimicrobial Properties of Multilayer Films with a Polyethylene/Silver Nanocomposite Layer , 2008 .

[2]  C. Häse,et al.  Chemiosmotic Mechanism of Antimicrobial Activity of Ag+ in Vibrio cholerae , 2002, Antimicrobial Agents and Chemotherapy.

[3]  R. Venkatesan,et al.  Biofouling studies on nanoparticle-based metal oxide coatings on glass coupons exposed to marine environment. , 2009, Colloids and surfaces. B, Biointerfaces.

[4]  Robert Soliva-Fortuny,et al.  Use of antimicrobial nanoemulsions as edible coatings: Impact on safety and quality attributes of fresh-cut Fuji apples , 2015 .

[5]  Guohua Zhao,et al.  Antimicrobial and physical properties of sweet potato starch films incorporated with potassium sorbate or chitosan , 2010 .

[6]  Arnab Roy,et al.  Characterization of enhanced antibacterial effects of novel silver nanoparticles , 2007, Nanotechnology.

[7]  V. Ahmadi,et al.  Growth and investigation of antifungal properties of ZnO nanorod arrays on the glass , 2011 .

[8]  N. Perkas,et al.  Coating of glass with ZnO via ultrasonic irradiation and a study of its antibacterial properties , 2009 .

[9]  H. Heinonen‐Tanski,et al.  Inactivation of enteric microorganisms with chemical disinfectants, UV irradiation and combined chemical/UV treatments. , 2005, Water research.

[10]  B. Ajitha,et al.  Biosynthesis of silver nanoparticles using Plectranthus amboinicus leaf extract and its antimicrobial activity. , 2014, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[11]  Kevin M. Smith,et al.  In Vitro and In Vivo Photosensitization by Protoporphyrins Possessing Different Lipophilicities and Vertical Localization in the Membrane , 2006, Photochemistry and photobiology.

[12]  Rajagopalan Vijayaraghavan,et al.  Enhanced bioactivity of ZnO nanoparticles—an antimicrobial study , 2008, Science and technology of advanced materials.

[13]  N. J. Andrade,et al.  Antimicrobial effects of silver nanoparticles against bacterial cells adhered to stainless steel surfaces. , 2012, Journal of food protection.

[14]  Michael T. Wilson,et al.  The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles. , 2009, Biomaterials.

[15]  M. Shahedi,et al.  Effect of nanocomposite packaging containing Ag and ZnO on inactivation of Lactobacillus plantarum in orange juice , 2011 .

[16]  Thomas J Webster,et al.  Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus , 2010, International journal of nanomedicine.

[17]  Jian-Cheng Deng,et al.  Preparation, characterization and antimicrobial activities of chitosan/Ag/ZnO blend films , 2010 .

[18]  H. Kastenholz,et al.  Public acceptance of nanotechnology foods and food packaging: The influence of affect and trust , 2007, Appetite.

[19]  Jana Soukupova,et al.  Effect of Surfactants and Polymers on Stability and Antibacterial Activity of Silver Nanoparticles (NPs) , 2008 .

[20]  Sudip Ray,et al.  The Potential Use of Polymer-Clay Nanocomposites in Food Packaging , 2006 .

[21]  Patricia Krawczak,et al.  Taguchi analysis of shrinkage and warpage of injection-moulded polypropylene/multiwall carbon nanotubes nanocomposites , 2009 .

[22]  J. Sawai,et al.  Detection of Active Oxygen Generated from Ceramic Powders Having Antibacterial Activity , 1996 .

[23]  M. Benedetti,et al.  Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. , 2006, Nano letters.

[24]  Milena Sinigaglia,et al.  Effect of Ag‐containing Nano‐composite Active Packaging System on Survival of Alicyclobacillus acidoterrestris , 2004 .

[25]  Bo-Jung Chen,et al.  Preparation and characterization of ZnO nanoparticles coated paper and its antibacterial activity study , 2006 .

[26]  Yasuyoshi Hayata,et al.  Development of TiO2 powder-coated food packaging film and its ability to inactivate Escherichia coli in vitro and in actual tests. , 2008, International journal of food microbiology.

[27]  Teruko Takano-Yamamoto,et al.  Effect of Cytokines on Osteoclast Formation and Bone Resorption during Mechanical Force Loading of the Periodontal Membrane , 2014, TheScientificWorldJournal.

[28]  Sourabh Shukla,et al.  Sonochemical coating of paper by microbiocidal silver nanoparticles. , 2011, Langmuir : the ACS journal of surfaces and colloids.

[29]  K. Ghosh,et al.  Mechanical properties of silver‐powder‐filled polypropylene composites , 1996 .

[30]  W. Stark,et al.  Highly sensitive optical detection of humidity on polymer/metal nanoparticle hybrid films. , 2007, Langmuir : the ACS journal of surfaces and colloids.

[31]  Yuan Hu,et al.  Catalyzing carbonization function of α-ZrP based intumescent fire retardant polypropylene nanocomposites , 2008 .

[32]  J. Baker,et al.  A novel surfactant nanoemulsion with a unique non-irritant topical antimicrobial activity against bacteria, enveloped viruses and fungi. , 2001, Microbiological research.

[33]  Rodney S. Ruoff,et al.  Polymer−Graphite Nanocomposites:  Effective Dispersion and Major Property Enhancement via Solid-State Shear Pulverization , 2008 .

[34]  A. Henglein Colloidal Silver Nanoparticles: Photochemical Preparation and Interaction with O2, CCl4, and Some Metal Ions , 1998 .

[35]  H. Honari,et al.  Comprehensive study of sporicidal and sporstatic effect of CuO and AgO metal nanoparticles upon spore of Clostridium botulinum type E , 2012 .

[36]  J. Song,et al.  Does the Antibacterial Activity of Silver Nanoparticles Depend on the Shape of the Nanoparticle? A Study of the Gram-Negative Bacterium Escherichia coli , 2007, Applied and Environmental Microbiology.

[37]  Chamorn Maneerat,et al.  Antifungal activity of TiO2 photocatalysis against Penicillium expansum in vitro and in fruit tests. , 2006, International journal of food microbiology.

[38]  Facundo Ruiz,et al.  Synthesis, characterization, and evaluation of antimicrobial and cytotoxic effect of silver and titanium nanoparticles. , 2010, Nanomedicine : nanotechnology, biology, and medicine.

[39]  M. Shahedi,et al.  Evaluation of nanocomposite packaging containing Ag and ZnO on shelf life of fresh orange juice , 2010 .

[40]  Milan Kolar,et al.  Silver colloid nanoparticles: synthesis, characterization, and their antibacterial activity. , 2006, The journal of physical chemistry. B.

[41]  C. Biliaderis,et al.  Physical properties of starch nanocrystal-reinforced pullulan films , 2007 .

[42]  Bo Zhang,et al.  Preparation and properties of poly(vinyl alcohol)/silica nanocomposites derived from copolymerization of vinyl silica nanoparticles and vinyl acetate , 2007 .

[43]  Q. Hu,et al.  Effect of nano-packing on preservation quality of fresh strawberry (Fragaria ananassa Duch. cv Fengxiang) during storage at 4 degrees C. , 2010, Journal of food science.

[44]  Peter L. Irwin,et al.  Antibacterial Activity and Mechanism of Action of Zinc Oxide Nanoparticles against Campylobacter jejuni , 2011, Applied and Environmental Microbiology.

[45]  Ann P. Dowling,et al.  Development of nanotechnologies , 2004 .

[46]  S. Rajeshkumar,et al.  In Vitro Antibacterial Activity and Mechanism of Silver Nanoparticles against Foodborne Pathogens , 2014, Bioinorganic chemistry and applications.

[47]  Darrin J Pochan,et al.  Synthesis and antibacterial properties of silver nanoparticles. , 2005, Journal of nanoscience and nanotechnology.

[48]  S. Ouda Some Nanoparticles Effects on Proteus sp. and Klebsiella Sp. Isolated from Water , 2014 .

[49]  D. Quintanar-Guerrero,et al.  The effect of nano-coatings with α-tocopherol and xanthan gum on shelf-life and browning index of fresh-cut “Red Delicious” apples , 2014 .

[50]  S. Prabhu,et al.  Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects , 2012, International Nano Letters.

[51]  F. Cui,et al.  A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. , 2000, Journal of biomedical materials research.

[52]  Jamie R Lead,et al.  Interactions of silver nanoparticles with Pseudomonas putida biofilms. , 2009, Environmental science & technology.

[53]  K. Whitehead,et al.  Titanium-coating of stainless steel as an aid to improved cleanability. , 2010, International journal of food microbiology.

[54]  A. Rahimpour,et al.  Coupling TiO2 nanoparticles with UV irradiation for modification of polyethersulfone ultrafiltration membranes , 2008 .

[55]  V. Vittoria,et al.  Potential perspectives of bio-nanocomposites for food packaging applications , 2007 .

[56]  Pierre Picouet,et al.  Reduction of the spoilage-related microflora in absorbent pads by silver nanotechnology during modified atmosphere packaging of beef meat. , 2010, Journal of food protection.

[57]  Sheng Li,et al.  Photoactive nanocoating for controlling microbial proliferation on polymeric surfaces , 2008 .

[58]  M. Laranjeira,et al.  Chitosan/poly (vinyl alcohol) films containing ZnO nanoparticles and plasticizers , 2010 .

[59]  Junhui He,et al.  Efficient fabrication of transparent antimicrobial poly(vinyl alcohol) thin films , 2009 .

[60]  Dohwan Kim,et al.  Bactericidal effect of TiO2 photocatalyst on selected food-borne pathogenic bacteria. , 2003, Chemosphere.

[61]  S. Ray,et al.  New Polylactide/Layered Silicate Nanocomposites, 6 , 2003 .

[62]  Eric A. Johnson,et al.  Clostridium botulinum and its neurotoxins: a metabolic and cellular perspective. , 2001, Toxicon : official journal of the International Society on Toxinology.

[63]  Shaojin Wang,et al.  Physical, chemical and microbiological changes in stored green asparagus spears as affected by coating of silver nanoparticles-PVP , 2008 .

[64]  K. Koutsoumanis,et al.  Physical and thermo-mechanical properties of whey protein isolate films containing antimicrobials, and their effect against spoilage flora of fresh beef , 2010 .

[65]  G. Mostafa,et al.  Facile synthesis of silver nano particles with highly efficient anti-microbial property , 2007 .

[66]  Rebecca M. Goulter,et al.  Attachment of different Salmonella serovars to materials commonly used in a poultry processing plant. , 2009, Food microbiology.

[67]  I. Sondi,et al.  Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. , 2004, Journal of colloid and interface science.

[68]  Lina Ghibelli,et al.  Copper Nanoparticle/Polymer Composites with Antifungal and Bacteriostatic Properties , 2005 .

[69]  Tsu-Wei Chou,et al.  Nanocomposites in context , 2005 .

[70]  R. Venkatesan,et al.  Mycobased synthesis of silver nanoparticles and their incorporation into sodium alginate films for vegetable and fruit preservation. , 2009, Journal of agricultural and food chemistry.

[71]  Nelson Durán,et al.  Nanobiotechnology perspectives. Role of nanotechnology in the food industry: a review , 2013 .

[72]  Qin Wang,et al.  Antioxidant and antimicrobial properties of essential oils encapsulated in zein nanoparticles prepared by liquid–liquid dispersion method , 2012 .

[73]  Hanguo Xiong,et al.  Effect of nano-SiO2 on the performance of starch/polyvinyl alcohol blend films , 2008 .

[74]  J. Sawai Quantitative evaluation of antibacterial activities of metallic oxide powders (ZnO, MgO and CaO) by conductimetric assay. , 2003, Journal of microbiological methods.

[75]  P. Halley,et al.  Macromolecular Interactions During Gelatinisation and Retrogradation in Starch-Whey Systems as Studied by Rapid Visco-Analyser , 2006 .

[76]  C. Narayanamurthy,et al.  Synthesis of metal incorporated low molecular weight polyurethanes from novel aromatic diols, their characterization and bactericidal properties. , 2004, Biomaterials.

[77]  T. Jin,et al.  Inactivation of Salmonella in liquid egg albumen by antimicrobial bottle coatings infused with allyl isothiocyanate, nisin and zinc oxide nanoparticles , 2011, Journal of applied microbiology.

[78]  Wei Jiang,et al.  Bacterial toxicity comparison between nano- and micro-scaled oxide particles. , 2009, Environmental pollution.

[79]  Karen M. Soto,et al.  Food Antimicrobials Nanocarriers , 2014, TheScientificWorldJournal.

[80]  Monty Liong,et al.  Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. , 2008, ACS nano.

[81]  T. Sa,et al.  Development of surfactin based nanoemulsion formulation from selected cooking oils: evaluation for antimicrobial activity against selected food associated microorganisms , 2012 .

[82]  Shan Zhao,et al.  An antimicrobial film by embedding in situ synthesized silver nanoparticles in soy protein isolate , 2013 .

[83]  A. Tripathi,et al.  Biocompatible nanoparticles trigger rapid bacteria clustering , 2008, Biotechnology progress.

[84]  Jianrong Chen,et al.  Nanotechnology and biosensors. , 2004, Biotechnology advances.

[85]  A. Gupta,et al.  Molecular Genetics: Silver as a biocide: Will resistance become a problem? , 1998, Nature Biotechnology.

[86]  Rodney S. Ruoff,et al.  Mechanical and thermal properties of carbon nanotubes , 1995 .

[87]  Lehui Lu,et al.  Hydrogen-bonding recognition-induced color change of gold nanoparticles for visual detection of melamine in raw milk and infant formula. , 2009, Journal of the American Chemical Society.

[88]  F. Donsì,et al.  Green beans preservation by combination of a modified chitosan based-coating containing nanoemulsion of mandarin essential oil with high pressure or pulsed light processing , 2015 .

[89]  K. Torigoe,et al.  Preparation and characterization of ultrafine metal particles in ethanol by UV irradiation using a photoinitiator , 1995 .

[90]  A. Mills Oxygen indicators and intelligent inks for packaging food. , 2005, Chemical Society reviews.

[91]  M. Meléndrez,et al.  Colloidal Cu nanoparticles/chitosan composite film obtained by microwave heating for food package applications , 2009 .

[92]  M. Yacamán,et al.  The bactericidal effect of silver nanoparticles , 2005, Nanotechnology.

[93]  Hans Bouwmeester,et al.  Potential Risks of Nanofood to Consumers , 2010 .

[94]  N. Chand,et al.  Copper (II) ions and copper nanoparticles‐loaded chemically modified cotton cellulose fibers with fair antibacterial properties , 2009 .

[95]  Maria Grazia Ammendolia,et al.  Listeria monocytogenes Behaviour in Presence of Non-UV-Irradiated Titanium Dioxide Nanoparticles , 2014, PloS one.

[96]  Qasim Chaudhry,et al.  Nanotechnologies in food , 2017 .

[97]  C. Bakis,et al.  Interfacial damping characteristics of carbon nanotube-based composites , 2004 .

[98]  E. Storgårds,et al.  Hygiene of Gasket Materials Used in Food Processing Equipment Part 2: Aged Materials , 1999 .

[99]  Ruchi Yadav,et al.  Biogenic synthesis of silver nanoparticles and their synergistic effect with antibiotics: a study against gram-positive and gram-negative bacteria. , 2010, Nanomedicine : nanotechnology, biology, and medicine.

[100]  R. Briandet,et al.  Inhibition of Listeria monocytogenes by resident biofilms present on wooden shelves used for cheese ripening , 2011 .

[101]  Toshio Kurauchi,et al.  Mechanical properties of nylon 6-clay hybrid , 1993 .

[102]  Effect of amine catalysts on preparation of nanometric SiO2 particles and antireflective films via sol–gel method , 2010 .

[103]  Tae-Hyun Bae,et al.  Effect of TiO2 nanoparticles on fouling mitigation of ultrafiltration membranes for activated sludge filtration , 2005 .

[104]  Seok-In Hong,et al.  Preparation and characterization of chitosan-based nanocomposite films with antimicrobial activity. , 2006, Journal of agricultural and food chemistry.

[105]  Tetsuaki Tsuchido,et al.  Mode of Bactericidal Action of Silver Zeolite and Its Comparison with That of Silver Nitrate , 2003, Applied and Environmental Microbiology.

[106]  Chun-Hua Yan,et al.  Hierarchical Construction of ZnO Architectures Promoted by Heterogeneous Nucleation , 2008 .

[107]  A. Akbar,et al.  Zinc oxide nanoparticles loaded active packaging, a challenge study against Salmonella typhimurium and Staphylococcus aureus in ready-to-eat poultry meat , 2014 .

[108]  S. Stoeva,et al.  Complex formation in solutions for chemical synthesis of nanoscaled particles prepared by borohydride reduction process , 1999 .

[109]  Dae Hong Jeong,et al.  Antimicrobial effects of silver nanoparticles. , 2007, Nanomedicine : nanotechnology, biology, and medicine.

[110]  T. E. Cloete,et al.  Application of nanotechnology in antimicrobial coatings in the water industry , 2011 .

[111]  Jeong-O Lee,et al.  Detection and titer estimation of Escherichia coli using aptamer-functionalized single-walled carbon-nanotube field-effect transistors. , 2008, Small.

[112]  M. Loessner,et al.  Antimicrobial Properties of a Novel Silver-Silica Nanocomposite Material , 2009, Applied and Environmental Microbiology.

[113]  P. Bechtel,et al.  Characterization of Fish-Skin Gelatin Gels and Films Containing the Antimicrobial Enzyme Lysozyme , 2006 .

[114]  Ji-Hyun Lee,et al.  Quality and microbial safety of ‘Fuji’ apples coated with carnauba-shellac wax containing lemongrass oil , 2014 .

[115]  Pierre Picouet,et al.  Cellulose-silver nanoparticle hybrid materials to control spoilage-related microflora in absorbent pads located in trays of fresh-cut melon. , 2010, International journal of food microbiology.

[116]  S. Dodd,et al.  The in vivo rat muscle force model is a reliable and clinically relevant test of consistency among botulinum toxin preparations. , 2008, Toxicon : official journal of the International Society on Toxinology.

[117]  Mark Stumborg,et al.  Green composites reinforced with hemp nanocrystals in plasticized starch , 2008 .

[118]  Ronghui Wang,et al.  TiO2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes. , 2009, Nano letters.

[119]  Wei Li Li,et al.  Antibacterial and Physical Properties of Poly(vinyl chloride)-based Film Coated with ZnO Nanoparticles , 2010, Food science and technology international = Ciencia y tecnologia de los alimentos internacional.

[120]  Xiuping Jiang,et al.  Rapid detection of Listeria monocytogenes by nanoparticle-based immunomagnetic separation and real-time PCR. , 2007, International journal of food microbiology.

[121]  T. Webster,et al.  Zinc oxide nanoparticle and polymer antimicrobial biomaterial composites , 2010, Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference (NEBEC).

[122]  K. Klabunde,et al.  Consolidation of Metal Oxide Nanocrystals. Reactive Pellets with Controllable Pore Structure That Represent a New Family of Porous, Inorganic Materials , 2000 .

[123]  L. Kotra,et al.  High-Resolution Atomic Force Microscopy Studies of the Escherichia coli Outer Membrane: Structural Basis for Permeability , 2000 .

[124]  G. McHale,et al.  A lichen protected by a super-hydrophobic and breathable structure. , 2006, Journal of plant physiology.

[125]  Rashmi Tiwari,et al.  Nanotechnology‐Enabled Delivery Systems for Food Functionalization and Fortification , 2012 .

[126]  S. Y. Wang,et al.  Preparation and characterization of whey protein film incorporated with TiO2 nanoparticles. , 2009, Journal of food science.

[127]  L. Mattoso,et al.  Nanocomposite edible films from mango puree reinforced with cellulose nanofibers. , 2009, Journal of food science.

[128]  Gihan M. El Moghazy,et al.  Detection of E.coli O157:H7 in feed samples using gold nanoparticles sensor , 2014 .

[129]  R. Moreira,et al.  Poly (DL-lactide-co-glycolide) (PLGA) nanoparticles with entrapped trans-cinnamaldehyde and eugenol for antimicrobial delivery applications. , 2011, Journal of food science.

[130]  Qi Zhou,et al.  Role of interface in dispersion and surface energetics of polymer nanocomposites containing hydrophilic POSS and layered silicates. , 2011, Journal of colloid and interface science.

[131]  S. Kim,et al.  Mechanical reinforcement and crystallization behavior of poly(ethylene 2,6-naphthalate) nanocomposites induced by modified carbon nanotube , 2009 .

[132]  S. Hussain,et al.  Lysozyme catalyzes the formation of antimicrobial silver nanoparticles. , 2009, ACS nano.

[133]  Alexander Wokaun,et al.  Nanoparticles in energy technology: examples from electrochemistry and catalysis. , 2005, Angewandte Chemie.

[134]  Richard M. Lueptow,et al.  Controlling biofilm growth using reactive ceramic ultrafiltration membranes , 2009 .

[135]  Efstathios Z Panagou,et al.  Use of titanium dioxide (TiO2) photocatalysts as alternative means for Listeria monocytogenes biofilm disinfection in food processing. , 2011, Food microbiology.

[136]  T. V. Duncan,et al.  Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors , 2011, Journal of Colloid and Interface Science.

[137]  J. Farkas,et al.  Nanotechnology and Microbial Food Safety , 2013 .

[138]  C. Perry,et al.  Antibiotic mediated synthesis of gold nanoparticles with potent antimicrobial activity and their application in antimicrobial coatings , 2010 .

[139]  Y. Wan,et al.  Introduction of broad spectrum antibacterial properties to bacterial cellulose nanofibers via immobilising ε-polylysine nanocoatings , 2014 .