The effect of diazepam on motor nerves and skeletal muscle

SummaryDiazepam exhibits various effects on motor nerves and skeletal muscle: 1. The maximum conduction velocity is decreased, 2. the duration of the negative component of the muscle action potential is increased, 3. the latency between the electrical and the mechanical response is increased, 4. the muscle contracts and 5. relaxes more slowly, and 6. the muscle force is reduced particularly with repetitive activation.ZusammenfassungDiazepam bewirkt im Bereich des motorischen Erfolgsorgans 1. eine Verzögerung der maximalen Nervenleitgeschwindigkeit, 2. eine Verbreiterung der negativen Phase des Muskelaktionspotentials, 3. eine Verlängerung der elektromechanischen Latenz, 4. eine Verlangsamung der Kontraktionsgeschwindigkeit und 5. der Erschlaffung des Muskels und 6. eine Reduktion der Muskelkraft auch für repetitive Kontraktionen.

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